mlsanityData to 13 Oct 2026

Standardization of Psychiatric Diagnoses -- Role of Fine-tuned LLM Consortium and OpenAI-gpt-oss Reasoning LLM Enabled Decision Support System

arXiv 2510.25588 ↗First posted 29 Oct 2025cs.AIcited by 12

On the map: LLM reasoning → Clinical and biomedical applications

Abstract (arXiv)

The diagnosis of most mental disorders, including psychiatric evaluations, primarily depends on dialogues between psychiatrists and patients. This subjective process can lead to variability in diagnoses across clinicians and patients, resulting in inconsistencies and challenges in achieving reliable outcomes. To address these issues and standardize psychiatric diagnoses, we propose a Fine-Tuned Large Language Model (LLM) Consortium and OpenAI-gpt-oss Reasoning LLM-enabled Decision Support System for the clinical diagnosis of mental disorders. Our approach leverages fine-tuned LLMs trained on conversational datasets involving psychiatrist-patient interactions focused on mental health conditions (e.g., depression). The diagnostic predictions from individual models are aggregated through a consensus-based decision-making process, refined by the OpenAI-gpt-oss reasoning LLM. We propose a novel method for deploying LLM agents that orchestrate communication between the LLM consortium and the reasoning LLM, ensuring transparency, reliability, and responsible AI across the entire diagnostic workflow. Experimental results demonstrate the transformative potential of combining fine-tuned LLMs with a reasoning model to create a robust and highly accurate diagnostic system for mental health assessment. A prototype of the proposed platform, integrating three fine-tuned LLMs with the OpenAI-gpt-oss reasoning LLM, was developed in collaboration with the U.S. Army Medical Research Team in Norfolk, Virginia, USA. To the best of our knowledge, this work represents the first application of a fine-tuned LLM consortium integrated with a reasoning LLM for clinical mental health diagnosis paving the way for next-generation AI-powered eHealth systems aimed at standardizing psychiatric diagnoses.

Key facts. Cited by 12 papers in the map (data through 13 Oct 2026). Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning. Builds on 24 of its 53 references that are in the map. First posted on arXiv 29 Oct 2025.

Builds on

24 of 53 references.

Closest ancestors · 2

Same direction, newest first

  1. 2025Proof-of-TBI -- Fine-Tuned Vision Language Model Consortium and OpenAI-o3 Reasoning LLM-Based Medical Diagnosis Support System for Mild Traumatic Brain Injury (TBI) Prediction25 Apr
  2. 2024DrHouse: An LLM-empowered Diagnostic Reasoning System through Harnessing Outcomes from Sensor Data and Expert Knowledge21 May

Other references · 22

  1. 2020Language Models are Few-Shot Learnerscited by 32,320
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  3. 2024Qwen2-VL: Enhancing Vision-Language Model's Perception of the World at Any Resolutioncited by 4,191
  4. 2023QLoRA: Efficient Finetuning of Quantized LLMscited by 3,388
  5. 2022Large Language Models Encode Clinical Knowledgecited by 1,817
  6. 2024LlamaFactory: Unified Efficient Fine-Tuning of 100+ Language Modelscited by 1,450
  7. 2025gpt-oss-120b & gpt-oss-20b Model Cardcited by 1,319
  8. 2024Understanding the planning of LLM agents: A surveycited by 416
  9. 2025Survey on Evaluation of LLM-based Agentscited by 200
  10. 2023Towards Accurate Differential Diagnosis with Large Language Modelscited by 116
  11. 2023Language Models Enable Simple Systems for Generating Structured Views of Heterogeneous Data Lakescited by 104
  12. 2024Data-efficient Fine-tuning for LLM-based Recommendationcited by 103
10 more
  1. 2024LLM as a Mastermind: A Survey of Strategic Reasoning with Large Language Modelscited by 98
  2. 2023Wider and Deeper LLM Networks are Fairer LLM Evaluatorscited by 92
  3. 2024LLM Unlearning via Loss Adjustment with Only Forget Datacited by 74
  4. 2025A Tutorial on LLM Reasoning: Relevant Methods behind ChatGPT o1cited by 25
  5. 2024MDD-5k: A New Diagnostic Conversation Dataset for Mental Disorders Synthesized via Neuro-Symbolic LLM Agentscited by 16
  6. 2024LoHan: Low-Cost High-Performance Framework to Fine-Tune 100B Model on a Consumer GPUcited by 10
  7. 2025VTutor: An Open-Source SDK for Generative AI-Powered Animated Pedagogical Agents with Multi-Media Outputcited by 7
  8. 2025Large Language Models for Interpretable Mental Health Diagnosiscited by 6
  9. 2025On-Device Qwen2.5: Efficient LLM Inference with Model Compression and Hardware Accelerationcited by 6
  10. 2024Advancements in Machine Learning and Deep Learning for Early Detection and Management of Mental Health Disordercited by 3

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Cited by year (2026 to 13 Oct)

Citing papers per year: 2025: 3; 2026: 9.

12 papers.

Similar, not cited

Close in wording, no citation either way

  1. 2026LingxiDiagBench: A Multi-Agent Framework for Benchmarking LLMs in Chinese Psychiatric Consultation and Diagnosis
  2. 2025LLAMADRS: Evaluating Open-Source LLMs on Real Clinical Interviews--To Reason or Not to Reason?
  3. 2025Trustworthy AI Psychotherapy: Multi-Agent LLM Workflow for Counseling and Explainable Mental Disorder Diagnosis
  4. 2026OMIND: Framework for Knowledge Grounded Finetuning and Multi-Turn Dialogue Benchmark for Mental Health LLMs
  5. 2026MentalSeek-Dx: Towards Progressive Hypothetico-Deductive Reasoning for Real-world Psychiatric Diagnosis
  6. 2025Reasoning Is Not All You Need: Examining LLMs for Multi-Turn Mental Health Conversations
  7. 2025WiseMind: a knowledge-guided multi-agent framework for accurate and empathetic psychiatric diagnosis
  8. 2026An Agentic LLM-Based Framework for Population-Scale Mental Health Screening