Reasoning Is Not All You Need: Examining LLMs for Multi-Turn Mental Health Conversations
On the map: LLM reasoning → Clinical and biomedical applications
Abstract (arXiv)
Limited access to mental healthcare, extended wait times, and increasing capabilities of Large Language Models (LLMs) has led individuals to turn to LLMs for fulfilling their mental health needs. However, examining the multi-turn mental health conversation capabilities of LLMs remains under-explored. Existing evaluation frameworks typically focus on diagnostic accuracy and win-rates and often overlook alignment with patient-specific goals, values, and personalities required for meaningful conversations. To address this, we introduce MedAgent, a novel framework for synthetically generating realistic, multi-turn mental health sensemaking conversations and use it to create the Mental Health Sensemaking Dialogue (MHSD) dataset, comprising over 2,200 patient-LLM conversations. Additionally, we present MultiSenseEval, a holistic framework to evaluate the multi-turn conversation abilities of LLMs in healthcare settings using human-centric criteria. Our findings reveal that frontier reasoning models yield below-par performance for patient-centric communication and struggle at advanced diagnostic capabilities with average score of 31%. Additionally, we observed variation in model performance based on patient's persona and performance drop with increasing turns in the conversation. Our work provides a comprehensive synthetic data generation framework, a dataset and evaluation framework for assessing LLMs in multi-turn mental health conversations.
Key facts. Cited by 6 papers in the map (data through 7 Oct 2026). Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning. Builds on 10 of its 52 references that are in the map. First posted on arXiv 26 May 2025.
Builds on
10 of 52 references.
Closest ancestors · 1
Same direction, newest first
- 2025Ask Patients with Patience: Enabling LLMs for Human-Centric Medical Dialogue with Grounded Reasoning11 Feb
Other references · 9
- 2025DeepSeek-R1: Incentivizing Reasoning Capability in LLMs via Reinforcement Learningcited by 6,146
- 2023Capabilities of GPT-4 on Medical Challenge Problemscited by 630
- 2025LLMs Get Lost In Multi-Turn Conversationcited by 400
- 2023Towards Expert-Level Medical Question Answering with Large Language Modelscited by 382
- 2025CultureVLM: Characterizing and Improving Cultural Understanding of Vision-Language Models for over 100 Countriescited by 40
- 2024Deconstructing The Ethics of Large Language Models from Long-standing Issues to New-emerging Dilemmas: A Surveycited by 23
- 2024MedHalu: Hallucinations in Responses to Healthcare Queries by Large Language Modelscited by 20
- 2023PsyEval: A Suite of Mental Health Related Tasks for Evaluating Large Language Modelscited by 13
- 2025Exploring the Inquiry-Diagnosis Relationship with Advanced Patient Simulatorscited by 8
Built on by
Citing papers per year: 2026: 6.
6 papers.
- 2026MASCOT: Multi-Agent Socio-Collaborative Companion Systemscited by 7
- 2026CALM-IT: Generating Realistic Long-Form Motivational Interviewing Dialogues with Dual-Actor Conversational Dynamics Trackingcited by 3
- 2026SafeTalkCoach: Diversity-Driven Multi-Agent Simulation for Parent-Teen Health Conversationscited by 0
- 2026A Systematic Evaluation of Large Language Models for PTSD Severity Estimation: The Role of Contextual Knowledge and Modeling Strategiescited by 0
- 2026Aligning with Lived Experience: Heterogeneous Benefits of Fine Tuning in Mental Health Support Generationcited by 0
- 2026From Pattern Recognizers to Personalized Companions: A Survey of Large Language Models in Mental Healthcited by 0
- 2026From Pattern Recognizers to Personalized Companions: A Survey of Large Language Models in Mental Health21 Sep 2026
- 2026Aligning with Lived Experience: Heterogeneous Benefits of Fine Tuning in Mental Health Support Generation17 Sep 2026
- 2026A Systematic Evaluation of Large Language Models for PTSD Severity Estimation: The Role of Contextual Knowledge and Modeling Strategies5 Feb 2026
- 2026MASCOT: Multi-Agent Socio-Collaborative Companion Systems20 Jan 2026
- 2026CALM-IT: Generating Realistic Long-Form Motivational Interviewing Dialogues with Dual-Actor Conversational Dynamics Tracking15 Jan 2026
- 2026SafeTalkCoach: Diversity-Driven Multi-Agent Simulation for Parent-Teen Health Conversations14 Jan 2026
Similar, not cited
Close in wording, no citation either way
- 2026OMIND: Framework for Knowledge Grounded Finetuning and Multi-Turn Dialogue Benchmark for Mental Health LLMs
- 2025MindEval: Benchmarking Language Models on Multi-turn Mental Health Support
- 2025LLAMADRS: Evaluating Open-Source LLMs on Real Clinical Interviews--To Reason or Not to Reason?
- 2026MedDialogRubrics: A Comprehensive Benchmark and Evaluation Framework for Multi-turn Medical Consultations in Large Language Models
- 2025Beyond Empathy: Integrating Diagnostic and Therapeutic Reasoning with Large Language Models for Mental Health Counseling
- 2025PsychBench: A comprehensive and professional benchmark for evaluating the performance of LLM-assisted psychiatric clinical practice
- 2026Reasoning Over Recall: Evaluating the Efficacy of Generalist Architectures vs. Specialized Fine-Tunes in RAG-Based Mental Health Dialogue Systems
- 2025Standardization of Psychiatric Diagnoses -- Role of Fine-tuned LLM Consortium and OpenAI-gpt-oss Reasoning LLM Enabled Decision Support System