mlsanityData to 14 Oct 2026

Generalist vs Specialist Time Series Foundation Models: Investigating Potential Emergent Behaviors in Assessing Human Health Using PPG Signals

arXiv 2510.14254 ↗First posted 16 Oct 2025cs.LGcited by 2

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Abstract (arXiv)

Foundation models are large-scale machine learning models that are pre-trained on massive amounts of data and can be adapted for various downstream tasks. They have been extensively applied to tasks in Natural Language Processing and Computer Vision with models such as GPT, BERT, and CLIP. They are now also increasingly gaining attention in time-series analysis, particularly for physiological sensing. However, most time series foundation models are specialist models - with data in pre-training and testing of the same type, such as Electrocardiogram, Electroencephalogram, and Photoplethysmogram (PPG). Recent works, such as MOMENT, train a generalist time series foundation model with data from multiple domains, such as weather, traffic, and electricity. This paper aims to conduct a comprehensive benchmarking study to compare the performance of generalist and specialist models, with a focus on PPG signals. Through an extensive suite of total 51 tasks covering cardiac state assessment, laboratory value estimation, and cross-modal inference, we comprehensively evaluate both models across seven dimensions, including win score, average performance, feature quality, tuning gain, performance variance, transferability, and scalability. These metrics jointly capture not only the models' capability but also their adaptability, robustness, and efficiency under different fine-tuning strategies, providing a holistic understanding of their strengths and limitations for diverse downstream scenarios. In a full-tuning scenario, we demonstrate that the specialist model achieves a 27% higher win score. Finally, we provide further analysis on generalization, fairness, attention visualizations, and the importance of training data choice.

Key facts. Cited by 2 papers in the map (data through 14 Oct 2026). Builds on 45 of its 80 references that are in the map. First posted on arXiv 16 Oct 2025.

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45 of 80 references.

References · 45

  1. 2018BERT: Pre-training of Deep Bidirectional Transformers for Language Understandingcited by 40,399
  2. 2021Learning Transferable Visual Models From Natural Language Supervisioncited by 33,744
  3. 2021High-Resolution Image Synthesis with Latent Diffusion Modelscited by 18,863
  4. 2023GPT-4 Technical Reportcited by 18,396
  5. 2023LLaMA: Open and Efficient Foundation Language Modelscited by 14,132
  6. 2020A Simple Framework for Contrastive Learning of Visual Representationscited by 12,049
  7. 2022Robust Speech Recognition via Large-Scale Weak Supervisioncited by 4,057
  8. 2024SAM 2: Segment Anything in Images and Videoscited by 2,863
  9. 2022A Time Series is Worth 64 Words: Long-term Forecasting with Transformerscited by 2,039
  10. 2019BioBERT: a pre-trained biomedical language representation model for biomedical text miningcited by 1,947
  11. 2020Domain-Specific Language Model Pretraining for Biomedical Natural Language Processingcited by 1,009
  12. 2024Chronos: Learning the Language of Time Seriescited by 759
33 more
  1. 2024MOMENT: A Family of Open Time-series Foundation Modelscited by 482
  2. 2021TS2Vec: Towards Universal Representation of Time Seriescited by 471
  3. 2020Med-BERT: pre-trained contextualized embeddings on large-scale structured electronic health records for disease predictioncited by 373
  4. 2019Unsupervised Scalable Representation Learning for Multivariate Time Seriescited by 269
  5. 2023Stabilizing Transformer Training by Preventing Attention Entropy Collapsecited by 161
  6. 2024Tiny Time Mixers (TTMs): Fast Pre-trained Models for Enhanced Zero/Few-Shot Forecasting of Multivariate Time Seriescited by 127
  7. 2023Large-scale Training of Foundation Models for Wearable Biosignalscited by 95
  8. 2024ECG-FM: An Open Electrocardiogram Foundation Modelcited by 90
  9. 2023Neuro-GPT: Towards A Foundation Model for EEGcited by 74
  10. 2024PaPaGei: Open Foundation Models for Optical Physiological Signalscited by 69
  11. 2025MedHELM: Holistic Evaluation of Large Language Models for Medical Taskscited by 64
  12. 2024Scaling Wearable Foundation Modelscited by 63
  13. 2024SleepFM: Multi-modal Representation Learning for Sleep Across Brain Activity, ECG and Respiratory Signalscited by 41
  14. 2025Pulse-PPG: An Open-Source Field-Trained PPG Foundation Model for Wearable Applications Across Lab and Field Settingscited by 37
  15. 2024Toward Foundation Model for Multivariate Wearable Sensing of Physiological Signalscited by 32
  16. 2024EEG-GPT: Exploring Capabilities of Large Language Models for EEG Classification and Interpretationcited by 27
  17. 2024An Electrocardiogram Foundation Model Built on over 10 Million Recordings with External Evaluation across Multiple Domainscited by 27
  18. 2025Beyond Sensor Data: Foundation Models of Behavioral Data from Wearables Improve Health Predictionscited by 18
  19. 2025GPT-PPG: A GPT-based Foundation Model for Photoplethysmography Signalscited by 15
  20. 2020Estimating Blood Pressure from Photoplethysmogram Signal and Demographic Features using Machine Learning Techniquescited by 13
  21. 2023ECGBERT: Understanding Hidden Language of ECGs with Self-Supervised Representation Learningcited by 12
  22. 2025OpenECG: Benchmarking ECG Foundation Models with Public 1.2 Million Recordscited by 11
  23. 2021MAUS: A Dataset for Mental Workload Assessmenton N-back Task Using Wearable Sensorcited by 7
  24. 2024Wearable-Based Real-time Freezing of Gait Detection in Parkinson's Disease Using Self-Supervised Learningcited by 6
  25. 2025PPG-Distill: Efficient Photoplethysmography Signals Analysis via Foundation Model Distillationcited by 6
  26. 2025LabTOP: A Unified Model for Lab Test Outcome Prediction on Electronic Health Recordscited by 5
  27. 2025Continuous Cardiac Arrest Prediction in ICU using PPG Foundation Modelcited by 2
  28. 2025Estimating Clinical Lab Test Result Trajectories from PPG using Physiological Foundation Model and Patient-Aware State Space Model -- a UNIPHY+ Approachcited by 2
  29. 2025A Unified AI Approach for Continuous Monitoring of Human Health and Diseases from Intensive Care Unit to Home with Physiological Foundation Models (UNIPHY+)cited by 2
  30. 2025FairTune: A Bias-Aware Fine-Tuning Framework Towards Fair Heart Rate Prediction from PPGcited by 2
  31. 2024Predicting the trajectory of intracranial pressure in patients with traumatic brain injury: evaluation of a foundation model for time seriescited by 1
  32. 2025Fusion of ECG Foundation Model Embeddings to Improve Early Detection of Acute Coronary Syndromescited by 1
  33. 2025Wav2Arrest 2.0: Long-Horizon Cardiac Arrest Prediction with Time-to-Event Modeling, Identity-Invariance, and Pseudo-Lab Alignmentcited by 1

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2 papers.