DiM: Diffusion Mamba for Efficient High-Resolution Image Synthesis
On the map: Diffusion models → Medical imaging and segmentation
Abstract (arXiv)
Diffusion models have achieved great success in image generation, with the backbone evolving from U-Net to Vision Transformers. However, the computational cost of Transformers is quadratic to the number of tokens, leading to significant challenges when dealing with high-resolution images. In this work, we propose Diffusion Mamba (DiM), which combines the efficiency of Mamba, a sequence model based on State Space Models (SSM), with the expressive power of diffusion models for efficient high-resolution image synthesis. To address the challenge that Mamba cannot generalize to 2D signals, we make several architecture designs including multi-directional scans, learnable padding tokens at the end of each row and column, and lightweight local feature enhancement. Our DiM architecture achieves inference-time efficiency for high-resolution images. In addition, to further improve training efficiency for high-resolution image generation with DiM, we investigate "weak-to-strong" training strategy that pretrains DiM on low-resolution images (256× 256) and then finetune it on high-resolution images (512 × 512). We further explore training-free upsampling strategies to enable the model to generate higher-resolution images (e.g., 1024× 1024 and 1536× 1536) without further fine-tuning. Experiments demonstrate the effectiveness and efficiency of our DiM. The code of our work is available here: urlhttps://github.com/tyshiwo1/DiM-DiffusionMamba/.
Key facts. Cited by 72 papers in the map (data through 14 Oct 2026). Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models. Builds on 31 of its 38 references that are in the map. First posted on arXiv 23 May 2024.
Builds on
31 of 38 references.
References · 31
- 2017Attention Is All You Needcited by 60,361
- 2020Denoising Diffusion Probabilistic Modelscited by 21,076
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,713
- 2021High-Resolution Image Synthesis with Latent Diffusion Modelscited by 18,863
- 2020Denoising Diffusion Implicit Modelscited by 9,781
- 2020Score-Based Generative Modeling through Stochastic Differential Equationscited by 9,122
- 2022Scalable Diffusion Models with Transformerscited by 6,054
- 2018A Style-Based Generator Architecture for Generative Adversarial Networkscited by 6,013
- 2023Mamba: Linear-Time Sequence Modeling with Selective State Spacescited by 4,718
- 2023SDXL: Improving Latent Diffusion Models for High-Resolution Image Synthesiscited by 4,356
- 2024Scaling Rectified Flow Transformers for High-Resolution Image Synthesiscited by 4,181
- 2023FlashAttention-2: Faster Attention with Better Parallelism and Work Partitioningcited by 2,598
19 more
- 2022DPM-Solver: A Fast ODE Solver for Diffusion Probabilistic Model Sampling in Around 10 Stepscited by 1,979
- 2024Vision Mamba: Efficient Visual Representation Learning with Bidirectional State Space Modelcited by 1,056
- 2024VMamba: Visual State Space Modelcited by 969
- 2022Simplified State Space Layers for Sequence Modelingcited by 788
- 2022All are Worth Words: A ViT Backbone for Diffusion Modelscited by 502
- 2022Hungry Hungry Hippos: Towards Language Modeling with State Space Modelscited by 499
- 2022On the Parameterization and Initialization of Diagonal State Space Modelscited by 424
- 2024VideoMamba: State Space Model for Efficient Video Understandingcited by 328
- 2016Dynamic Filter Networkscited by 319
- 2024Hunyuan-DiT: A Powerful Multi-Resolution Diffusion Transformer with Fine-Grained Chinese Understandingcited by 298
- 2023PaLI-X: On Scaling up a Multilingual Vision and Language Modelcited by 255
- 2024Lumina-T2X: Transforming Text into Any Modality, Resolution, and Duration via Flow-based Large Diffusion Transformerscited by 137
- 2022How to Train Your HiPPO: State Space Models with Generalized Orthogonal Basis Projectionscited by 122
- 2024Video Mamba Suite: State Space Model as a Versatile Alternative for Video Understandingcited by 108
- 2023Diffusion Models Without Attentioncited by 75
- 2022Your ViT is Secretly a Hybrid Discriminative-Generative Diffusion Modelcited by 58
- 2024Scalable Diffusion Models with State Space Backbonecited by 45
- 2024Dual-path Mamba: Short and Long-term Bidirectional Selective Structured State Space Models for Speech Separationcited by 45
- 2024Upsample Guidance: Scale Up Diffusion Models without Trainingcited by 20
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Citing papers per year: 2024: 28; 2025: 29; 2026: 15.
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- 2026PDE-SSM: A Spectral State Space Approach to Spatial Mixing in Diffusion Transformers14 Mar 2026
- 2026Efficient Long-Sequence Diffusion Modeling for Symbolic Music Generation28 Feb 2026
- 2026Adaptive 1D Video Diffusion Autoencoder4 Feb 2026
- 2026PixelGen: Improving Pixel Diffusion with Perceptual Supervision2 Feb 2026
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- 2025MoMa: Modulating Mamba for Adapting Image Foundation Models to Video Recognition29 Jun 2025
- 2025Mamba-Adaptor: State Space Model Adaptor for Visual Recognition19 May 2025
- 2025Mesh Mamba: A Unified State Space Model for Saliency Prediction in Non-Textured and Textured Meshes2 Apr 2025
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- 2025Speculative Jacobi-Denoising Decoding for Accelerating Autoregressive Text-to-image Generation10 Oct 2025
- 2025Polyline Path Masked Attention for Vision Transformer19 Jun 2025
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- 2025ViT-Linearizer: Distilling Quadratic Knowledge into Linear-Time Vision Models30 Mar 2025
- 2025Taming Teacher Forcing for Masked Autoregressive Video Generation21 Jan 2025
- 2024V"Mean"ba: Visual State Space Models only need 1 hidden dimension21 Dec 2024
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