MedExpQA: Multilingual Benchmarking of Large Language Models for Medical Question Answering
On the map: Retrieval-augmented generation → Medical and biomedical RAG
Abstract (arXiv)
Large Language Models (LLMs) have the potential of facilitating the development of Artificial Intelligence technology to assist medical experts for interactive decision support, which has been demonstrated by their competitive performances in Medical QA. However, while impressive, the required quality bar for medical applications remains far from being achieved. Currently, LLMs remain challenged by outdated knowledge and by their tendency to generate hallucinated content. Furthermore, most benchmarks to assess medical knowledge lack reference gold explanations which means that it is not possible to evaluate the reasoning of LLMs predictions. Finally, the situation is particularly grim if we consider benchmarking LLMs for languages other than English which remains, as far as we know, a totally neglected topic. In order to address these shortcomings, in this paper we present MedExpQA, the first multilingual benchmark based on medical exams to evaluate LLMs in Medical Question Answering. To the best of our knowledge, MedExpQA includes for the first time reference gold explanations written by medical doctors which can be leveraged to establish various gold-based upper-bounds for comparison with LLMs performance. Comprehensive multilingual experimentation using both the gold reference explanations and Retrieval Augmented Generation (RAG) approaches show that performance of LLMs still has large room for improvement, especially for languages other than English. Furthermore, and despite using state-of-the-art RAG methods, our results also demonstrate the difficulty of obtaining and integrating readily available medical knowledge that may positively impact results on downstream evaluations for Medical Question Answering. So far the benchmark is available in four languages, but we hope that this work may encourage further development to other languages.
Key facts. Cited by 43 papers in the map (data through 7 Oct 2026). Placed in Medical and biomedical RAG, one of 15 directions in Retrieval-augmented generation. Builds on 25 of its 43 references that are in the map. First posted on arXiv 8 Apr 2024.
Builds on
25 of 43 references.
Closest ancestors · 2
Same direction, newest first
- 2024Benchmarking Retrieval-Augmented Generation for Medicine20 Feb
- 2023Almanac: Retrieval-Augmented Language Models for Clinical Medicine1 Mar
Other references · 23
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- 2020What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Examscited by 1,324
- 2019PubMedQA: A Dataset for Biomedical Research Question Answeringcited by 1,271
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- 2023Capabilities of GPT-4 on Medical Challenge Problemscited by 630
- 2022BioGPT: Generative Pre-trained Transformer for Biomedical Text Generation and Miningcited by 531
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- 2024BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domainscited by 299
- 2023MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Datacited by 282
- 2023MedCPT: Contrastive Pre-trained Transformers with Large-scale PubMed Search Logs for Zero-shot Biomedical Information Retrievalcited by 182
- 2019HEAD-QA: A Healthcare Dataset for Complex Reasoningcited by 100
- 2021SciFive: a text-to-text transformer model for biomedical literaturecited by 99
- 2023PMC-LLaMA: Towards Building Open-source Language Models for Medicinecited by 87
- 2023ClinicalGPT: Large Language Models Finetuned with Diverse Medical Data and Comprehensive Evaluationcited by 85
- 2023Explanatory Argument Extraction of Correct Answers in Resident Medical Examscited by 6
- 2023HiTZ@Antidote: Argumentation-driven Explainable Artificial Intelligence for Digital Medicinecited by 5
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Citing papers per year: 2024: 7; 2025: 21; 2026: 15.
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