Multilingual Medical Reasoning for Question Answering with Large Language Models
On the map: LLM reasoning → Clinical and biomedical applications
Abstract (arXiv)
Large Language Models (LLMs) with reasoning capabilities have recently demonstrated strong potential in medical Question Answering (QA). Existing approaches are largely English-focused and primarily rely on distillation from general-purpose LLMs, raising concerns about the reliability of their medical knowledge. In this work, we present a method to generate multilingual reasoning traces based on medical knowledge extracted from Wikipedia. We produce 500k traces in English, Italian, and Spanish, using a retrieval-augmented generation approach over medical information from Wikipedia. The traces are generated to solve medical questions drawn from MedQA and MedMCQA, which we extend to Italian and Spanish. We test our pipeline in both in-domain and out-of-domain settings across Medical QA benchmarks, and demonstrate that our reasoning traces improve performance both when utilized via in-context learning (few-shot) and supervised fine-tuning, yielding state-of-the-art results among 8B-parameter LLMs. We believe that these resources can support the development of more transparent clinical decision-support tools in multilingual settings. We release the full suite of resources: reasoning traces, translated QA datasets, Medical-Wikipedia, and fine-tuned models.
Key facts. Cited by 2 papers in the map (data through 7 Oct 2026). Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning. Builds on 4 of its 49 references that are in the map. First posted on arXiv 5 Dec 2025.
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4 of 49 references.
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- 2025Beyond Distillation: Pushing the Limits of Medical LLM Reasoning with Minimalist Rule-Based RL23 May
- 2025Disentangling Reasoning and Knowledge in Medical Large Language Models16 May
- 2025MedReason: Eliciting Factual Medical Reasoning Steps in LLMs via Knowledge Graphs1 Apr
Other references · 1
- 2024OpenAI o1 System Cardcited by 1,220
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Citing papers per year: 2026: 2.
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- 2025MKG-Rank: Enhancing Large Language Models with Knowledge Graph for Multilingual Medical Question Answering
- 2024MedExpQA: Multilingual Benchmarking of Large Language Models for Medical Question Answering
- 2026Med-CoReasoner: Reducing Language Disparities in Medical Reasoning via Language-Informed Co-Reasoning
- 2025IMB: An Italian Medical Benchmark for Question Answering
- 2025PersianMedQA: Evaluating Large Language Models on a Persian-English Bilingual Medical Question Answering Benchmark
- 2025MediQAl: A French Medical Question Answering Dataset for Knowledge and Reasoning Evaluation
- 2024LLM-MedQA: Enhancing Medical Question Answering through Case Studies in Large Language Models
- 2023MKRAG: Medical Knowledge Retrieval Augmented Generation for Medical Question Answering