mlsanityData to 7 Oct 2026

Denoising Diffusion Semantic Segmentation with Mask Prior Modeling

arXiv 2306.01721 ↗First posted 2 Jun 2023cs.CV cs.AIcited by 15

On the map: Diffusion models → Medical imaging and segmentation

Abstract (arXiv)

The evolution of semantic segmentation has long been dominated by learning more discriminative image representations for classifying each pixel. Despite the prominent advancements, the priors of segmentation masks themselves, e.g., geometric and semantic constraints, are still under-explored. In this paper, we propose to ameliorate the semantic segmentation quality of existing discriminative approaches with a mask prior modeled by a recently-developed denoising diffusion generative model. Beginning with a unified architecture that adapts diffusion models for mask prior modeling, we focus this work on a specific instantiation with discrete diffusion and identify a variety of key design choices for its successful application. Our exploratory analysis revealed several important findings, including: (1) a simple integration of diffusion models into semantic segmentation is not sufficient, and a poorly-designed diffusion process might lead to degradation in segmentation performance; (2) during the training, the object to which noise is added is more important than the type of noise; (3) during the inference, the strict diffusion denoising scheme may not be essential and can be relaxed to a simpler scheme that even works better. We evaluate the proposed prior modeling with several off-the-shelf segmentors, and our experimental results on ADE20K and Cityscapes demonstrate that our approach could achieve competitively quantitative performance and more appealing visual quality.

Key facts. Cited by 15 papers in the map (data through 7 Oct 2026). Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models. Builds on 78 of its 89 references that are in the map. First posted on arXiv 2 Jun 2023.

Builds on

78 of 89 references.

Closest ancestors · 7

Same direction, newest first

  1. 2023MedSegDiff-V2: Diffusion based Medical Image Segmentation with Transformer19 Jan
  2. 2022DiffusionInst: Diffusion Model for Instance Segmentation6 Dec
  3. 2022Peekaboo: Text to Image Diffusion Models are Zero-Shot Segmentors23 Nov
  4. 2022MedSegDiff: Medical Image Segmentation with Diffusion Probabilistic Model1 Nov
  5. 2021Diffusion Models for Implicit Image Segmentation Ensembles6 Dec
  6. 2021Label-Efficient Semantic Segmentation with Diffusion Models6 Dec
  7. 2021SegDiff: Image Segmentation with Diffusion Probabilistic Models1 Dec

Other references · 71

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38 more
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Citing papers per year: 2023: 7; 2024: 5; 2025: 1; 2026: 2.

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  1. 2023Masked Diffusion as Self-supervised Representation Learner
  2. 2024MaskDiffusion: Exploiting Pre-trained Diffusion Models for Semantic Segmentation
  3. 2026Diffusion Model as a Generalist Segmentation Learner
  4. 2024Diffusion Features to Bridge Domain Gap for Semantic Segmentation
  5. 2024EmerDiff: Emerging Pixel-level Semantic Knowledge in Diffusion Models
  6. 2023Diffusion Model is Secretly a Training-free Open Vocabulary Semantic Segmenter
  7. 2023Conditional Diffusion Models for Weakly Supervised Medical Image Segmentation
  8. 2023Stochastic Segmentation with Conditional Categorical Diffusion Models