Unsupervised Model Adaptation for Source-free Segmentation of Medical Images
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Abstract (arXiv)
The recent prevalence of deep neural networks has lead semantic segmentation networks to achieve human-level performance in the medical field when sufficient training data is provided. Such networks however fail to generalize when tasked with predicting semantic maps for out-of-distribution images, requiring model re-training on the new distributions. This expensive process necessitates expert knowledge in order to generate training labels. Distribution shifts can arise naturally in the medical field via the choice of imaging device, i.e. MRI or CT scanners. To combat the need for labeling images in a target domain after a model is successfully trained in a fully annotated textitsource domain with a different data distribution, unsupervised domain adaptation (UDA) can be used. Most UDA approaches ensure target generalization by creating a shared source/target latent feature space. This allows a source trained classifier to maintain performance on the target domain. However most UDA approaches require joint source and target data access, which may create privacy leaks with respect to patient information. We propose an UDA algorithm for medical image segmentation that does not require access to source data during adaptation, and is thus capable in maintaining patient data privacy. We rely on an approximation of the source latent features at adaptation time, and create a joint source/target embedding space by minimizing a distributional distance metric based on optimal transport. We demonstrate our approach is competitive to recent UDA medical segmentation works even with the added privacy requisite.
Key facts. Cited by 13 papers in the map (data through 14 Oct 2026). Builds on 62 of its 99 references that are in the map. First posted on arXiv 2 Nov 2022.
Builds on
62 of 99 references.
References · 62
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38 more
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Citing papers per year: 2023: 2; 2024: 6; 2025: 3; 2026: 2.
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- 2025Surgical Scene Understanding in the Era of Foundation AI Models: A Comprehensive Reviewcited by 8
- 2024Navigating Distribution Shifts in Medical Image Analysis: A Surveycited by 5
- 2024Harmonizing Flows: Leveraging normalizing flows for unsupervised and source-free MRI harmonizationcited by 4
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- 2023Graph Harmony: Denoising and Nuclear-Norm Wasserstein Adaptation for Enhanced Domain Transfer in Graph-Structured Datacited by 2
- 2024FIESTA: Fourier-Based Semantic Augmentation with Uncertainty Guidance for Enhanced Domain Generalizability in Medical Image Segmentationcited by 2
- 2024Cross-Domain Distribution Alignment for Segmentation of Private Unannotated 3D Medical Imagescited by 1
- 2026ProCal: Probability Calibration for Neighborhood-Guided Source-Free Domain Adaptationcited by 1
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- 2025pMixFed: Efficient Personalized Federated Learning through Adaptive Layer-Wise Mixup19 Jan 2025
- 2024Navigating Distribution Shifts in Medical Image Analysis: A Survey5 Nov 2024
- 2024Cross-Domain Distribution Alignment for Segmentation of Private Unannotated 3D Medical Images11 Oct 2024
- 2024Curvature Diversity-Driven Deformation and Domain Alignment for Point Cloud3 Oct 2024
- 2024Harmonizing Flows: Leveraging normalizing flows for unsupervised and source-free MRI harmonization22 Jul 2024
- 2024FIESTA: Fourier-Based Semantic Augmentation with Uncertainty Guidance for Enhanced Domain Generalizability in Medical Image Segmentation20 Jun 2024
- 2024Unsupervised Domain Adaptation Using Compact Internal Representations14 Jan 2024
- 2023Robust Internal Representations for Domain Generalization27 Sep 2023
- 2025Surgical Scene Understanding in the Era of Foundation AI Models: A Comprehensive Reviewcited by 8
- 2024Navigating Distribution Shifts in Medical Image Analysis: A Surveycited by 5
- 2024Harmonizing Flows: Leveraging normalizing flows for unsupervised and source-free MRI harmonizationcited by 4
- 2025pMixFed: Efficient Personalized Federated Learning through Adaptive Layer-Wise Mixupcited by 3
- 2023Graph Harmony: Denoising and Nuclear-Norm Wasserstein Adaptation for Enhanced Domain Transfer in Graph-Structured Datacited by 2
- 2024FIESTA: Fourier-Based Semantic Augmentation with Uncertainty Guidance for Enhanced Domain Generalizability in Medical Image Segmentationcited by 2
- 2024Cross-Domain Distribution Alignment for Segmentation of Private Unannotated 3D Medical Imagescited by 1
- 2026ProCal: Probability Calibration for Neighborhood-Guided Source-Free Domain Adaptationcited by 1
- 2023Robust Internal Representations for Domain Generalizationcited by 0
- 2024Unsupervised Domain Adaptation Using Compact Internal Representationscited by 0
- 2024Curvature Diversity-Driven Deformation and Domain Alignment for Point Cloudcited by 0
- 2025Cross-domain Few-shot Object Detection with Multi-modal Textual Enrichmentcited by 0
- 2026ProCal: Probability Calibration for Neighborhood-Guided Source-Free Domain Adaptation19 Mar 2026
- 2025Cross-domain Few-shot Object Detection with Multi-modal Textual Enrichment23 Feb 2025
- 2025Surgical Scene Understanding in the Era of Foundation AI Models: A Comprehensive Review16 Feb 2025
- 2025pMixFed: Efficient Personalized Federated Learning through Adaptive Layer-Wise Mixup19 Jan 2025
- 2024Navigating Distribution Shifts in Medical Image Analysis: A Survey5 Nov 2024
- 2024Cross-Domain Distribution Alignment for Segmentation of Private Unannotated 3D Medical Images11 Oct 2024
- 2024Curvature Diversity-Driven Deformation and Domain Alignment for Point Cloud3 Oct 2024
- 2024Harmonizing Flows: Leveraging normalizing flows for unsupervised and source-free MRI harmonization22 Jul 2024
- 2024FIESTA: Fourier-Based Semantic Augmentation with Uncertainty Guidance for Enhanced Domain Generalizability in Medical Image Segmentation20 Jun 2024
- 2024Unsupervised Domain Adaptation Using Compact Internal Representations14 Jan 2024
- 2023Robust Internal Representations for Domain Generalization27 Sep 2023
- 2023Graph Harmony: Denoising and Nuclear-Norm Wasserstein Adaptation for Enhanced Domain Transfer in Graph-Structured Data29 Jan 2023