Designing Reinforcement Learning Algorithms for Digital Interventions: Pre-implementation Guidelines
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Abstract (arXiv)
Online reinforcement learning (RL) algorithms are increasingly used to personalize digital interventions in the fields of mobile health and online education. Common challenges in designing and testing an RL algorithm in these settings include ensuring the RL algorithm can learn and run stably under real-time constraints, and accounting for the complexity of the environment, e.g., a lack of accurate mechanistic models for the user dynamics. To guide how one can tackle these challenges, we extend the PCS (Predictability, Computability, Stability) framework, a data science framework that incorporates best practices from machine learning and statistics in supervised learning (Yu and Kumbier, 2020), to the design of RL algorithms for the digital interventions setting. Further, we provide guidelines on how to design simulation environments, a crucial tool for evaluating RL candidate algorithms using the PCS framework. We illustrate the use of the PCS framework for designing an RL algorithm for Oralytics, a mobile health study aiming to improve users' tooth-brushing behaviors through the personalized delivery of intervention messages. Oralytics will go into the field in late 2022.
Key facts. Cited by 22 papers in the map (data through 14 Oct 2026). Builds on 23 of its 51 references that are in the map. First posted on arXiv 8 Jun 2022.
Builds on
23 of 51 references.
References · 23
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Citing papers per year: 2022: 1; 2023: 7; 2024: 8; 2025: 4; 2026: 2.
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- 2022Reward Design For An Online Reinforcement Learning Algorithm Supporting Oral Self-Carecited by 18
- 2024Peeking with PEAK: Sequential, Nonparametric Composite Hypothesis Tests for Means of Multiple Data Streamscited by 9
- 2025Stable Thompson Sampling: Valid Inference via Variance Inflationcited by 8
- 2024reBandit: Random Effects based Online RL algorithm for Reducing Cannabis Usecited by 6
- 2023Efficient and robust transfer learning of optimal individualized treatment regimes with right-censored survival datacited by 5
- 2026Reinforcement Learning in the Real World: A Survey of Statistical Challenges and Future Directionscited by 5
- 2023Contextual Bandits with Budgeted Information Revealcited by 3
- 2023The Unintended Consequences of Discount Regularization: Improving Regularization in Certainty Equivalence Reinforcement Learningcited by 3
- 2024Monitoring Fidelity of Online Reinforcement Learning Algorithms in Clinical Trialscited by 3
- 2023Thompson sampling for zero-inflated count outcomes with an application to the Drink Less mobile health studycited by 2
- 2024Reinforcement Learning Interventions on Boundedly Rational Human Agents in Frictionful Taskscited by 2
- 2024Oralytics Reinforcement Learning Algorithmcited by 2
10 more
- 2025Reinforcement Learning on Dyads to Enhance Medication Adherencecited by 2
- 2023Dyadic Reinforcement Learningcited by 1
- 2024The Fallacy of Minimizing Cumulative Regret in the Sequential Task Settingcited by 1
- 2024Prompting the Unknown: Understanding Response Uncertainty in Large Language Modelscited by 1
- 2024Effective Monitoring of Online Decision-Making Algorithms in Digital Intervention Implementationcited by 1
- 2025Reproducible workflow for online AI in digital healthcited by 1
- 2023Synthetic Data Generator for Adaptive Interventions in Global Healthcited by 0
- 2023Designing and evaluating an online reinforcement learning agent for physical exercise recommendations in N-of-1 trialscited by 0
- 2025Can we use LLMs to bootstrap reinforcement learning? -- A case study in digital health behavior changecited by 0
- 2026The Evidence Ladder for Reinforcement Learning in Healthcare: From Retrospective Policies to Trusted Interventionscited by 0
- 2026The Evidence Ladder for Reinforcement Learning in Healthcare: From Retrospective Policies to Trusted Interventions20 Sep 2026
- 2026Reinforcement Learning in the Real World: A Survey of Statistical Challenges and Future Directions21 Jan 2026
- 2025Can we use LLMs to bootstrap reinforcement learning? -- A case study in digital health behavior change19 Nov 2025
- 2025Reproducible workflow for online AI in digital health16 Sep 2025
- 2025Stable Thompson Sampling: Valid Inference via Variance Inflation29 May 2025
- 2025Reinforcement Learning on Dyads to Enhance Medication Adherence6 Feb 2025
- 2024Effective Monitoring of Online Decision-Making Algorithms in Digital Intervention Implementation30 Aug 2024
- 2024Prompting the Unknown: Understanding Response Uncertainty in Large Language Models20 Jul 2024
- 2024Oralytics Reinforcement Learning Algorithm19 Jun 2024
- 2024The Fallacy of Minimizing Cumulative Regret in the Sequential Task Setting16 Mar 2024
- 2024reBandit: Random Effects based Online RL algorithm for Reducing Cannabis Use27 Feb 2024
- 2024Monitoring Fidelity of Online Reinforcement Learning Algorithms in Clinical Trials26 Feb 2024
10 more
- 2024Peeking with PEAK: Sequential, Nonparametric Composite Hypothesis Tests for Means of Multiple Data Streams9 Feb 2024
- 2024Reinforcement Learning Interventions on Boundedly Rational Human Agents in Frictionful Tasks26 Jan 2024
- 2023Thompson sampling for zero-inflated count outcomes with an application to the Drink Less mobile health study24 Nov 2023
- 2023Designing and evaluating an online reinforcement learning agent for physical exercise recommendations in N-of-1 trials25 Sep 2023
- 2023Dyadic Reinforcement Learning15 Aug 2023
- 2023The Unintended Consequences of Discount Regularization: Improving Regularization in Certainty Equivalence Reinforcement Learning20 Jun 2023
- 2023Contextual Bandits with Budgeted Information Reveal29 May 2023
- 2023Synthetic Data Generator for Adaptive Interventions in Global Health3 Mar 2023
- 2023Efficient and robust transfer learning of optimal individualized treatment regimes with right-censored survival data13 Jan 2023
- 2022Reward Design For An Online Reinforcement Learning Algorithm Supporting Oral Self-Care15 Aug 2022
- 2026Reinforcement Learning in the Real World: A Survey of Statistical Challenges and Future Directionscited by 5
- 2024Monitoring Fidelity of Online Reinforcement Learning Algorithms in Clinical Trialscited by 3
- 2024Reinforcement Learning Interventions on Boundedly Rational Human Agents in Frictionful Taskscited by 2
- 2024Oralytics Reinforcement Learning Algorithmcited by 2
- 2025Reinforcement Learning on Dyads to Enhance Medication Adherencecited by 2
- 2024The Fallacy of Minimizing Cumulative Regret in the Sequential Task Settingcited by 1
- 2026The Evidence Ladder for Reinforcement Learning in Healthcare: From Retrospective Policies to Trusted Interventionscited by 0
- 2026The Evidence Ladder for Reinforcement Learning in Healthcare: From Retrospective Policies to Trusted Interventions20 Sep 2026
- 2026Reinforcement Learning in the Real World: A Survey of Statistical Challenges and Future Directions21 Jan 2026
- 2025Reinforcement Learning on Dyads to Enhance Medication Adherence6 Feb 2025
- 2024Oralytics Reinforcement Learning Algorithm19 Jun 2024
- 2024The Fallacy of Minimizing Cumulative Regret in the Sequential Task Setting16 Mar 2024
- 2024Monitoring Fidelity of Online Reinforcement Learning Algorithms in Clinical Trials26 Feb 2024
- 2024Reinforcement Learning Interventions on Boundedly Rational Human Agents in Frictionful Tasks26 Jan 2024
- 2022Reward Design For An Online Reinforcement Learning Algorithm Supporting Oral Self-Carecited by 18
- 2024Peeking with PEAK: Sequential, Nonparametric Composite Hypothesis Tests for Means of Multiple Data Streamscited by 9
- 2025Stable Thompson Sampling: Valid Inference via Variance Inflationcited by 8
- 2024reBandit: Random Effects based Online RL algorithm for Reducing Cannabis Usecited by 6
- 2023Efficient and robust transfer learning of optimal individualized treatment regimes with right-censored survival datacited by 5
- 2023Contextual Bandits with Budgeted Information Revealcited by 3
- 2023The Unintended Consequences of Discount Regularization: Improving Regularization in Certainty Equivalence Reinforcement Learningcited by 3
- 2023Thompson sampling for zero-inflated count outcomes with an application to the Drink Less mobile health studycited by 2
- 2023Dyadic Reinforcement Learningcited by 1
- 2024Prompting the Unknown: Understanding Response Uncertainty in Large Language Modelscited by 1
- 2024Effective Monitoring of Online Decision-Making Algorithms in Digital Intervention Implementationcited by 1
- 2025Reproducible workflow for online AI in digital healthcited by 1
12 most cited of 14 All 14 (JSON)
- 2025Reproducible workflow for online AI in digital health16 Sep 2025
- 2025Stable Thompson Sampling: Valid Inference via Variance Inflation29 May 2025
- 2024Effective Monitoring of Online Decision-Making Algorithms in Digital Intervention Implementation30 Aug 2024
- 2024Prompting the Unknown: Understanding Response Uncertainty in Large Language Models20 Jul 2024
- 2024reBandit: Random Effects based Online RL algorithm for Reducing Cannabis Use27 Feb 2024
- 2024Peeking with PEAK: Sequential, Nonparametric Composite Hypothesis Tests for Means of Multiple Data Streams9 Feb 2024
- 2023Thompson sampling for zero-inflated count outcomes with an application to the Drink Less mobile health study24 Nov 2023
- 2023Designing and evaluating an online reinforcement learning agent for physical exercise recommendations in N-of-1 trials25 Sep 2023
- 2023Dyadic Reinforcement Learning15 Aug 2023
- 2023The Unintended Consequences of Discount Regularization: Improving Regularization in Certainty Equivalence Reinforcement Learning20 Jun 2023
- 2023Contextual Bandits with Budgeted Information Reveal29 May 2023
- 2023Synthetic Data Generator for Adaptive Interventions in Global Health3 Mar 2023
12 newest of 14 All 14 (JSON)