RF-HiT: Rectified Flow Hierarchical Transformer for General Medical Image Segmentation
On the map: Diffusion models → Medical imaging and segmentation
Abstract (arXiv)
Accurate medical image segmentation requires both long-range contextual reasoning and precise boundary delineation, a task where existing transformer- and diffusion-based paradigms are frequently bottlenecked by quadratic computational complexity and prohibitive inference latency. We propose RF-HiT, a Rectified Flow Hierarchical Transformer that integrates an Hourglass Transformer backbone with a multi-scale hierarchical encoder for anatomically guided feature conditioning. Unlike prior diffusion-based approaches that rely on hundreds of denoising steps, RF-HiT leverages rectified flow with efficient transformer blocks, achieving linear complexity and requiring only a few discretization steps. The model further fuses conditioning features at each resolution via learnable interpolation, enabling effective multi-scale feature integration with minimal computational overhead. As a result, RF-HiT achieves a strong efficiency-performance trade-off, requiring only 10.14 GFLOPs, 13.6M parameters, and inference in as few as 3 steps. Despite its compact design, RF-HiT attains 91.27% mean Dice on ACDC and 87.40% on BraTS 2021, achieving performance comparable to or exceeding that of significantly more intensive architectures. These results suggest that RF-HiT is a promising, computationally efficient foundation for clinical image segmentation.
Key facts. No citing papers in the map yet (data through 14 Oct 2026). Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models. Builds on 27 of its 30 references that are in the map. First posted on arXiv 21 Apr 2026.
Builds on
27 of 30 references.
Closest ancestors · 5
Same direction, newest first
- 2025SegDT: A Diffusion Transformer-Based Segmentation Model for Medical Imaging21 Jul
- 2023Diff-UNet: A Diffusion Embedded Network for Volumetric Segmentation18 Mar
- 2023MedSegDiff-V2: Diffusion based Medical Image Segmentation with Transformer19 Jan
- 2021Diffusion Models for Implicit Image Segmentation Ensembles6 Dec
- 2021SegDiff: Image Segmentation with Diffusion Probabilistic Models1 Dec
Other references · 22
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- 2021TransUNet: Transformers Make Strong Encoders for Medical Image Segmentationcited by 1,558
- 2021Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentationcited by 1,222
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10 more
- 2021UNETR: Transformers for 3D Medical Image Segmentationcited by 959
- 2022Swin UNETR: Swin Transformers for Semantic Segmentation of Brain Tumors in MRI Imagescited by 830
- 2024Movie Gen: A Cast of Media Foundation Modelscited by 644
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