HistoSeg : Quick attention with multi-loss function for multi-structure segmentation in digital histology images
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Abstract (arXiv)
Medical image segmentation assists in computer-aided diagnosis, surgeries, and treatment. Digitize tissue slide images are used to analyze and segment glands, nuclei, and other biomarkers which are further used in computer-aided medical applications. To this end, many researchers developed different neural networks to perform segmentation on histological images, mostly these networks are based on encoder-decoder architecture and also utilize complex attention modules or transformers. However, these networks are less accurate to capture relevant local and global features with accurate boundary detection at multiple scales, therefore, we proposed an Encoder-Decoder Network, Quick Attention Module and a Multi Loss Function (combination of Binary Cross Entropy (BCE) Loss, Focal Loss & Dice Loss). We evaluate the generalization capability of our proposed network on two publicly available datasets for medical image segmentation MoNuSeg and GlaS and outperform the state-of-the-art networks with 1.99% improvement on the MoNuSeg dataset and 7.15% improvement on the GlaS dataset. Implementation Code is available at this link: https://bit.ly/HistoSeg
Key facts. Cited by 17 papers in the map (data through 7 Oct 2026). Builds on 17 of its 26 references that are in the map. First posted on arXiv 1 Sep 2022.
Builds on
17 of 26 references.
References · 17
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
- 2014Fully Convolutional Networks for Semantic Segmentationcited by 4,845
- 2018Encoder-Decoder with Atrous Separable Convolution for Semantic Image Segmentationcited by 3,210
- 2021TransUNet: Transformers Make Strong Encoders for Medical Image Segmentationcited by 1,552
- 2021Transformers in Vision: A Surveycited by 1,009
- 2019UNet++: Redesigning Skip Connections to Exploit Multiscale Features in Image Segmentationcited by 583
- 2019Stand-Alone Self-Attention in Vision Modelscited by 542
- 2017Residual Attention Network for Image Classificationcited by 385
- 2020Axial-DeepLab: Stand-Alone Axial-Attention for Panoptic Segmentationcited by 326
- 2021Medical Transformer: Gated Axial-Attention for Medical Image Segmentationcited by 319
- 2016Gland Segmentation in Colon Histology Images: The GlaS Challenge Contestcited by 203
- 2020DoubleU-Net: A Deep Convolutional Neural Network for Medical Image Segmentationcited by 125
5 more
- 2021MISSFormer: An Effective Medical Image Segmentation Transformercited by 103
- 2019Multi-scale self-guided attention for medical image segmentationcited by 84
- 2021MSRF-Net: A Multi-Scale Residual Fusion Network for Biomedical Image Segmentationcited by 53
- 2019Context-Aware Convolutional Neural Network for Grading of Colorectal Cancer Histology Imagescited by 39
- 2020Generative Adversarial Networks for Automatic Polyp Segmentationcited by 5
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Citing papers per year: 2023: 4; 2024: 5; 2025: 5; 2026: 3.
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- 2023Exploring Transfer Learning in Medical Image Segmentation using Vision-Language Modelscited by 28
- 2024Segment Any Cell: A SAM-based Auto-prompting Fine-tuning Framework for Nuclei Segmentationcited by 24
- 2023TransNuSeg: A Lightweight Multi-Task Transformer for Nuclei Segmentationcited by 14
- 2023Narrowing the semantic gaps in U-Net with learnable skip connections: The case of medical image segmentationcited by 9
- 2024Semi-Self-Supervised Domain Adaptation: Developing Deep Learning Models with Limited Annotated Data for Wheat Head Segmentationcited by 5
- 2024GRU-Net: Gaussian Attention Aided Dense Skip Connection Based MultiResUNet for Breast Histopathology Image Segmentationcited by 4
- 2025A Large-scale Benchmark on Geological Fault Delineation Models: Domain Shift, Training Dynamics, Generalizability, Evaluation and Inferential Behaviorcited by 4
- 2025Rethinking Decoder Design: Improving Biomarker Segmentation Using Depth-to-Space Restoration and Residual Linear Attentioncited by 4
- 2024Drawing the Line: Deep Segmentation for Extracting Art from Ancient Etruscan Mirrorscited by 3
- 2025PathSegDiff: Pathology Segmentation using Diffusion model representationscited by 3
- 2026Low Cost, High Efficiency: LiDAR Place Recognition in Vineyards with Matryoshka Representation Learningcited by 2
- 2025Rethinking the Nested U-Net Approach: Enhancing Biomarker Segmentation with Attention Mechanisms and Multiscale Feature Fusioncited by 1
5 more
- 2025Is Exchangeability better than I.I.D to handle Data Distribution Shifts while Pooling Data for Data-scarce Medical image segmentation?cited by 1
- 2023The State of Applying Artificial Intelligence to Tissue Imaging for Cancer Research and Early Detectioncited by 0
- 2024A Survey on Cell Nuclei Instance Segmentation and Classification: Leveraging Context and Attentioncited by 0
- 2026MedCAGD: Context-Aware Gated Decoder for Efficient Medical Image Segmentationcited by 0
- 2026HistoSeg++: Delving deeper with attention and multiscale feature fusion for biomarker segmentationcited by 0
- 2026HistoSeg++: Delving deeper with attention and multiscale feature fusion for biomarker segmentation2 Jul 2026
- 2026MedCAGD: Context-Aware Gated Decoder for Efficient Medical Image Segmentation1 Jul 2026
- 2026Low Cost, High Efficiency: LiDAR Place Recognition in Vineyards with Matryoshka Representation Learning26 Jan 2026
- 2025Is Exchangeability better than I.I.D to handle Data Distribution Shifts while Pooling Data for Data-scarce Medical image segmentation?25 Jul 2025
- 2025Rethinking Decoder Design: Improving Biomarker Segmentation Using Depth-to-Space Restoration and Residual Linear Attention23 Jun 2025
- 2025A Large-scale Benchmark on Geological Fault Delineation Models: Domain Shift, Training Dynamics, Generalizability, Evaluation and Inferential Behavior13 May 2025
- 2025PathSegDiff: Pathology Segmentation using Diffusion model representations9 Apr 2025
- 2025Rethinking the Nested U-Net Approach: Enhancing Biomarker Segmentation with Attention Mechanisms and Multiscale Feature Fusion8 Apr 2025
- 2024A Survey on Cell Nuclei Instance Segmentation and Classification: Leveraging Context and Attention26 Jul 2024
- 2024GRU-Net: Gaussian Attention Aided Dense Skip Connection Based MultiResUNet for Breast Histopathology Image Segmentation12 Jun 2024
- 2024Semi-Self-Supervised Domain Adaptation: Developing Deep Learning Models with Limited Annotated Data for Wheat Head Segmentation12 May 2024
- 2024Drawing the Line: Deep Segmentation for Extracting Art from Ancient Etruscan Mirrors24 Apr 2024
5 more
- 2024Segment Any Cell: A SAM-based Auto-prompting Fine-tuning Framework for Nuclei Segmentation24 Jan 2024
- 2023Narrowing the semantic gaps in U-Net with learnable skip connections: The case of medical image segmentation23 Dec 2023
- 2023Exploring Transfer Learning in Medical Image Segmentation using Vision-Language Models15 Aug 2023
- 2023TransNuSeg: A Lightweight Multi-Task Transformer for Nuclei Segmentation16 Jul 2023
- 2023The State of Applying Artificial Intelligence to Tissue Imaging for Cancer Research and Early Detection29 Jun 2023
- 2024Segment Any Cell: A SAM-based Auto-prompting Fine-tuning Framework for Nuclei Segmentationcited by 24
- 2023TransNuSeg: A Lightweight Multi-Task Transformer for Nuclei Segmentationcited by 14
- 2023Narrowing the semantic gaps in U-Net with learnable skip connections: The case of medical image segmentationcited by 9
- 2024Semi-Self-Supervised Domain Adaptation: Developing Deep Learning Models with Limited Annotated Data for Wheat Head Segmentationcited by 5
- 2024GRU-Net: Gaussian Attention Aided Dense Skip Connection Based MultiResUNet for Breast Histopathology Image Segmentationcited by 4
- 2025A Large-scale Benchmark on Geological Fault Delineation Models: Domain Shift, Training Dynamics, Generalizability, Evaluation and Inferential Behaviorcited by 4
- 2025Rethinking Decoder Design: Improving Biomarker Segmentation Using Depth-to-Space Restoration and Residual Linear Attentioncited by 4
- 2024Drawing the Line: Deep Segmentation for Extracting Art from Ancient Etruscan Mirrorscited by 3
- 2026Low Cost, High Efficiency: LiDAR Place Recognition in Vineyards with Matryoshka Representation Learningcited by 2
- 2025Rethinking the Nested U-Net Approach: Enhancing Biomarker Segmentation with Attention Mechanisms and Multiscale Feature Fusioncited by 1
- 2025Is Exchangeability better than I.I.D to handle Data Distribution Shifts while Pooling Data for Data-scarce Medical image segmentation?cited by 1
- 2023The State of Applying Artificial Intelligence to Tissue Imaging for Cancer Research and Early Detectioncited by 0
12 most cited of 15 All 15 (JSON)
- 2026HistoSeg++: Delving deeper with attention and multiscale feature fusion for biomarker segmentation2 Jul 2026
- 2026MedCAGD: Context-Aware Gated Decoder for Efficient Medical Image Segmentation1 Jul 2026
- 2026Low Cost, High Efficiency: LiDAR Place Recognition in Vineyards with Matryoshka Representation Learning26 Jan 2026
- 2025Is Exchangeability better than I.I.D to handle Data Distribution Shifts while Pooling Data for Data-scarce Medical image segmentation?25 Jul 2025
- 2025Rethinking Decoder Design: Improving Biomarker Segmentation Using Depth-to-Space Restoration and Residual Linear Attention23 Jun 2025
- 2025A Large-scale Benchmark on Geological Fault Delineation Models: Domain Shift, Training Dynamics, Generalizability, Evaluation and Inferential Behavior13 May 2025
- 2025Rethinking the Nested U-Net Approach: Enhancing Biomarker Segmentation with Attention Mechanisms and Multiscale Feature Fusion8 Apr 2025
- 2024A Survey on Cell Nuclei Instance Segmentation and Classification: Leveraging Context and Attention26 Jul 2024
- 2024GRU-Net: Gaussian Attention Aided Dense Skip Connection Based MultiResUNet for Breast Histopathology Image Segmentation12 Jun 2024
- 2024Semi-Self-Supervised Domain Adaptation: Developing Deep Learning Models with Limited Annotated Data for Wheat Head Segmentation12 May 2024
- 2024Drawing the Line: Deep Segmentation for Extracting Art from Ancient Etruscan Mirrors24 Apr 2024
- 2024Segment Any Cell: A SAM-based Auto-prompting Fine-tuning Framework for Nuclei Segmentation24 Jan 2024
12 newest of 15 All 15 (JSON)