SA-UNet: Spatial Attention U-Net for Retinal Vessel Segmentation
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Abstract (arXiv)
The precise segmentation of retinal blood vessels is of great significance for early diagnosis of eye-related diseases such as diabetes and hypertension. In this work, we propose a lightweight network named Spatial Attention U-Net (SA-UNet) that does not require thousands of annotated training samples and can be utilized in a data augmentation manner to use the available annotated samples more efficiently. SA-UNet introduces a spatial attention module which infers the attention map along the spatial dimension, and multiplies the attention map by the input feature map for adaptive feature refinement. In addition, the proposed network employs structured dropout convolutional blocks instead of the original convolutional blocks of U-Net to prevent the network from overfitting. We evaluate SA-UNet based on two benchmark retinal datasets: the Vascular Extraction (DRIVE) dataset and the Child Heart and Health Study (CHASE_DB1) dataset. The results show that the proposed SA-UNet achieves state-of-the-art performance on both datasets.The implementation and the trained networks are available on Github1.
Key facts. Cited by 71 papers in the map (data through 13 Oct 2026). First posted on arXiv 7 Apr 2020.
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Citing papers per year: 2021: 13; 2022: 12; 2023: 15; 2024: 17; 2025: 9; 2026: 5.
71 papers.
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- 2022Medical Image Segmentation Review: The success of U-Netcited by 191
- 2021Efficient Medical Image Segmentation Based on Knowledge Distillationcited by 43
- 2021FANet: A Feedback Attention Network for Improved Biomedical Image Segmentationcited by 36
- 2024WE-GS: An In-the-wild Efficient 3D Gaussian Representation for Unconstrained Photo Collectionscited by 33
- 2021Study Group Learning: Improving Retinal Vessel Segmentation Trained with Noisy Labelscited by 20
- 2024Serp-Mamba: Advancing High-Resolution Retinal Vessel Segmentation with Selective State-Space Modelcited by 20
- 2023DA-TransUNet: Integrating Spatial and Channel Dual Attention with Transformer U-Net for Medical Image Segmentationcited by 16
- 2022A survey on attention mechanisms for medical applications: are we moving towards better algorithms?cited by 15
- 2023Feature Enhancer Segmentation Network (FES-Net) for Vessel Segmentationcited by 10
- 2023Attention Mechanisms in Medical Image Segmentation: A Surveycited by 9
- 2022Orientation and Context Entangled Network for Retinal Vessel Segmentationcited by 8
- 2023Channel prior convolutional attention for medical image segmentationcited by 8
38 more
- 2022Graph Flow: Cross-layer Graph Flow Distillation for Dual Efficient Medical Image Segmentationcited by 7
- 2021Explainable Diabetic Retinopathy Detection and Retinal Image Generationcited by 6
- 2022SuperVessel: Segmenting High-resolution Vessel from Low-resolution Retinal Imagecited by 6
- 2023LUNet: Deep Learning for the Segmentation of Arterioles and Venules in High Resolution Fundus Imagescited by 6
- 2024Explainable Convolutional Neural Networks for Retinal Fundus Classification and Cutting-Edge Segmentation Models for Retinal Blood Vessels from Fundus Imagescited by 6
- 2021CoCo DistillNet: a Cross-layer Correlation Distillation Network for Pathological Gastric Cancer Segmentationcited by 5
- 2021PAENet: A Progressive Attention-Enhanced Network for 3D to 2D Retinal Vessel Segmentationcited by 4
- 2023Deep Learning for Iris Recognition: A Reviewcited by 4
- 2021EAR-NET: Error Attention Refining Network For Retinal Vessel Segmentationcited by 3
- 2022Retinal Vessel Segmentation with Pixel-wise Adaptive Filterscited by 3
- 2025Full-scale Representation Guided Network for Retinal Vessel Segmentationcited by 3
- 2021PATO: Producibility-Aware Topology Optimization using Deep Learning for Metal Additive Manufacturingcited by 2
- 2022L^3U-net: Low-Latency Lightweight U-net Based Image Segmentation Model for Parallel CNN Processorscited by 2
- 2023SCOPE: Structural Continuity Preservation for Medical Image Segmentationcited by 2
- 2023FS-Net: Full Scale Network and Adaptive Threshold for Improving Extraction of Micro-Retinal Vessel Structurescited by 2
- 2024Benchmarking Retinal Blood Vessel Segmentation Models for Cross-Dataset and Cross-Disease Generalizationcited by 2
- 2024Retinal Vessel Segmentation with Deep Graph and Capsule Reasoningcited by 2
- 2025MDF-MLLM: Deep Fusion Through Cross-Modal Feature Alignment for Contextually Aware Fundoscopic Image Classificationcited by 2
- 2025Residual-SwinCA-Net: A Channel-Aware Integrated Residual CNN-Swin Transformer for Malignant Lesion Segmentation in BUSIcited by 2
- 2021Self-Supervised Vessel Enhancement Using Flow-Based Consistenciescited by 1
- 2021Attention W-Net: Improved Skip Connections for better Representationscited by 1
- 2021Localized Feature Aggregation Module for Semantic Segmentationcited by 1
- 2022MC-UNet Multi-module Concatenation based on U-shape Network for Retinal Blood Vessels Segmentationcited by 1
- 2022Impact of loss function in Deep Learning methods for accurate retinal vessel segmentationcited by 1
- 2022Weakly-Supervised Crack Detectioncited by 1
- 2023Multi-dimensional Fusion and Consistency for Semi-supervised Medical Image Segmentationcited by 1
- 2024DeepBranchTracer: A Generally-Applicable Approach to Curvilinear Structure Reconstruction Using Multi-Feature Learningcited by 1
- 2024A Mutual Inclusion Mechanism for Precise Boundary Segmentation in Medical Imagescited by 1
- 2024Practical Guidelines for Cell Segmentation Models Under Optical Aberrations in Microscopycited by 1
- 2024RICAU-Net: Residual-block Inspired Coordinate Attention U-Net for Segmentation of Small and Sparse Calcium Lesions in Cardiac CTcited by 1
- 2025SA-UNetv2: Rethinking Spatial Attention U-Net for Retinal Vessel Segmentationcited by 1
- 2026DeltaSeg: Tiered Attention and Deep Delta Learning for Multi-Class Structural Defect Segmentationcited by 1
- 2021Multi-View Stereo Network with attention thin volumecited by 0
- 2021RA V-Net: Deep learning network for automated liver segmentationcited by 0
- 2022Exploring the Effects of Data Augmentation for Drivable Area Segmentationcited by 0
- 2022The Development of Spatial Attention U-Net for The Recovery of Ionospheric Measurements and The Extraction of Ionospheric Parameterscited by 0
- 2023MAF-Net: Multiple attention-guided fusion network for fundus vascular image segmentationcited by 0
- 2023Elongated Physiological Structure Segmentation via Spatial and Scale Uncertainty-aware Networkcited by 0
50 most cited of 71 All 71 (JSON)
- 2026CGDD-Net: Context-Guided Dynamic Detail Modeling for Retinal Vessel Segmentation4 Oct 2026
- 2026APRIL-MedSeg: A Modular Medical Image Segmentation Toolbox Embracing Modern Paradigms29 Jun 2026
- 2026From Convolution to Transformer: A Comparative Study of U-Net Variants for Brain Tumor and Retinal Vessel Segmentation20 Jun 2026
- 2026DeltaSeg: Tiered Attention and Deep Delta Learning for Multi-Class Structural Defect Segmentation20 Apr 2026
- 2026HMS-VesselNet: Hierarchical Multi-Scale Attention Network with Topology-Preserving Loss for Retinal Vessel Segmentation23 Mar 2026
- 2025Residual-SwinCA-Net: A Channel-Aware Integrated Residual CNN-Swin Transformer for Malignant Lesion Segmentation in BUSI9 Dec 2025
- 2025MDF-MLLM: Deep Fusion Through Cross-Modal Feature Alignment for Contextually Aware Fundoscopic Image Classification21 Sep 2025
- 2025Fracture interactive geodesic active contours for bone segmentation18 Sep 2025
- 2025SA-UNetv2: Rethinking Spatial Attention U-Net for Retinal Vessel Segmentation15 Sep 2025
- 2025Uncertainty-Aware Retinal Vessel Segmentation via Ensemble Distillation15 Sep 2025
- 2025KARMA: Efficient Structural Defect Segmentation via Kolmogorov-Arnold Representation Learning11 Aug 2025
- 2025FORTRESS: Function-composition Optimized Real-Time Resilient Structural Segmentation via Kolmogorov-Arnold Enhanced Spatial Attention Networks16 Jul 2025
38 more
- 2025A Deep Convolutional Neural Network-Based Novel Class Balancing for Imbalance Data Segmentation23 Jun 2025
- 2025Full-scale Representation Guided Network for Retinal Vessel Segmentation31 Jan 2025
- 2024Optimized Vessel Segmentation: A Structure-Agnostic Approach with Small Vessel Enhancement and Morphological Correction22 Nov 2024
- 2024S3TU-Net: Structured Convolution and Superpixel Transformer for Lung Nodule Segmentation19 Nov 2024
- 2024Retinal Vessel Segmentation via Neuron Programming17 Nov 2024
- 2024MDFI-Net: Multiscale Differential Feature Interaction Network for Accurate Retinal Vessel Segmentation20 Oct 2024
- 2024Retinal Vessel Segmentation with Deep Graph and Capsule Reasoning17 Sep 2024
- 2024RICAU-Net: Residual-block Inspired Coordinate Attention U-Net for Segmentation of Small and Sparse Calcium Lesions in Cardiac CT11 Sep 2024
- 2024Serp-Mamba: Advancing High-Resolution Retinal Vessel Segmentation with Selective State-Space Model6 Sep 2024
- 2024Benchmarking Retinal Blood Vessel Segmentation Models for Cross-Dataset and Cross-Disease Generalization21 Jun 2024
- 2024Evaluation of Blood Vessel Segmentation Methods on Hard-to-Detect Vascular Structures19 Jun 2024
- 2024WE-GS: An In-the-wild Efficient 3D Gaussian Representation for Unconstrained Photo Collections4 Jun 2024
- 2024Image-level Regression for Uncertainty-aware Retinal Image Segmentation27 May 2024
- 2024Automatic diagnosis of cardiac magnetic resonance images based on semi-supervised learning23 May 2024
- 2024Explainable Convolutional Neural Networks for Retinal Fundus Classification and Cutting-Edge Segmentation Models for Retinal Blood Vessels from Fundus Images12 May 2024
- 2024Practical Guidelines for Cell Segmentation Models Under Optical Aberrations in Microscopy12 Apr 2024
- 2024A Mutual Inclusion Mechanism for Precise Boundary Segmentation in Medical Images12 Apr 2024
- 2024FESS Loss: Feature-Enhanced Spatial Segmentation Loss for Optimizing Medical Image Analysis13 Feb 2024
- 2024DeepBranchTracer: A Generally-Applicable Approach to Curvilinear Structure Reconstruction Using Multi-Feature Learning2 Feb 2024
- 2023Bayesian Neural Networks for 2D MRI Segmentation24 Nov 2023
- 2023FS-Net: Full Scale Network and Adaptive Threshold for Improving Extraction of Micro-Retinal Vessel Structures14 Nov 2023
- 2023DA-TransUNet: Integrating Spatial and Channel Dual Attention with Transformer U-Net for Medical Image Segmentation19 Oct 2023
- 20233D SA-UNet: 3D Spatial Attention UNet with 3D Atrous Spatial Pyramid Pooling for White Matter Hyperintensities Segmentation15 Sep 2023
- 2023Multi-dimensional Fusion and Consistency for Semi-supervised Medical Image Segmentation12 Sep 2023
- 2023LUNet: Deep Learning for the Segmentation of Arterioles and Venules in High Resolution Fundus Images11 Sep 2023
- 2023Feature Enhancer Segmentation Network (FES-Net) for Vessel Segmentation7 Sep 2023
- 2023SA Unet Improved18 Aug 2023
- 2023Channel prior convolutional attention for medical image segmentation8 Jun 2023
- 2023Overview of Deep Learning Methods for Retinal Vessel Segmentation1 Jun 2023
- 2023Elongated Physiological Structure Segmentation via Spatial and Scale Uncertainty-aware Network30 May 2023
- 2023Attention Mechanisms in Medical Image Segmentation: A Survey29 May 2023
- 2023MAF-Net: Multiple attention-guided fusion network for fundus vascular image segmentation5 May 2023
- 2023SCOPE: Structural Continuity Preservation for Medical Image Segmentation28 Apr 2023
- 2023Deep Learning for Iris Recognition: A Review15 Mar 2023
- 2022Medical Image Segmentation Review: The success of U-Net27 Nov 2022
- 2022The Development of Spatial Attention U-Net for The Recovery of Ionospheric Measurements and The Extraction of Ionospheric Parameters15 Sep 2022
- 2022Exploring the Effects of Data Augmentation for Drivable Area Segmentation6 Aug 2022
- 2022SuperVessel: Segmenting High-resolution Vessel from Low-resolution Retinal Image28 Jul 2022
50 newest of 71 All 71 (JSON)
- 2022Medical Image Segmentation Review: The success of U-Netcited by 191
- 2021FANet: A Feedback Attention Network for Improved Biomedical Image Segmentationcited by 36
- 2024WE-GS: An In-the-wild Efficient 3D Gaussian Representation for Unconstrained Photo Collectionscited by 33
- 2021Study Group Learning: Improving Retinal Vessel Segmentation Trained with Noisy Labelscited by 20
- 2023DA-TransUNet: Integrating Spatial and Channel Dual Attention with Transformer U-Net for Medical Image Segmentationcited by 16
- 2022A survey on attention mechanisms for medical applications: are we moving towards better algorithms?cited by 15
- 2023Feature Enhancer Segmentation Network (FES-Net) for Vessel Segmentationcited by 10
- 2023Attention Mechanisms in Medical Image Segmentation: A Surveycited by 9
- 2022Orientation and Context Entangled Network for Retinal Vessel Segmentationcited by 8
- 2023Channel prior convolutional attention for medical image segmentationcited by 8
- 2022Graph Flow: Cross-layer Graph Flow Distillation for Dual Efficient Medical Image Segmentationcited by 7
- 2021Explainable Diabetic Retinopathy Detection and Retinal Image Generationcited by 6
12 most cited of 68 All 68 (JSON)
- 2026CGDD-Net: Context-Guided Dynamic Detail Modeling for Retinal Vessel Segmentation4 Oct 2026
- 2026APRIL-MedSeg: A Modular Medical Image Segmentation Toolbox Embracing Modern Paradigms29 Jun 2026
- 2026From Convolution to Transformer: A Comparative Study of U-Net Variants for Brain Tumor and Retinal Vessel Segmentation20 Jun 2026
- 2026DeltaSeg: Tiered Attention and Deep Delta Learning for Multi-Class Structural Defect Segmentation20 Apr 2026
- 2026HMS-VesselNet: Hierarchical Multi-Scale Attention Network with Topology-Preserving Loss for Retinal Vessel Segmentation23 Mar 2026
- 2025Residual-SwinCA-Net: A Channel-Aware Integrated Residual CNN-Swin Transformer for Malignant Lesion Segmentation in BUSI9 Dec 2025
- 2025MDF-MLLM: Deep Fusion Through Cross-Modal Feature Alignment for Contextually Aware Fundoscopic Image Classification21 Sep 2025
- 2025Fracture interactive geodesic active contours for bone segmentation18 Sep 2025
- 2025SA-UNetv2: Rethinking Spatial Attention U-Net for Retinal Vessel Segmentation15 Sep 2025
- 2025Uncertainty-Aware Retinal Vessel Segmentation via Ensemble Distillation15 Sep 2025
- 2025KARMA: Efficient Structural Defect Segmentation via Kolmogorov-Arnold Representation Learning11 Aug 2025
- 2025FORTRESS: Function-composition Optimized Real-Time Resilient Structural Segmentation via Kolmogorov-Arnold Enhanced Spatial Attention Networks16 Jul 2025
12 newest of 68 All 68 (JSON)