Study Group Learning: Improving Retinal Vessel Segmentation Trained with Noisy Labels
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Abstract (arXiv)
Retinal vessel segmentation from retinal images is an essential task for developing the computer-aided diagnosis system for retinal diseases. Efforts have been made on high-performance deep learning-based approaches to segment the retinal images in an end-to-end manner. However, the acquisition of retinal vessel images and segmentation labels requires onerous work from professional clinicians, which results in smaller training dataset with incomplete labels. As known, data-driven methods suffer from data insufficiency, and the models will easily over-fit the small-scale training data. Such a situation becomes more severe when the training vessel labels are incomplete or incorrect. In this paper, we propose a Study Group Learning (SGL) scheme to improve the robustness of the model trained on noisy labels. Besides, a learned enhancement map provides better visualization than conventional methods as an auxiliary tool for clinicians. Experiments demonstrate that the proposed method further improves the vessel segmentation performance in DRIVE and CHASE_DB1 datasets, especially when the training labels are noisy.
Key facts. Cited by 20 papers in the map (data through 14 Oct 2026). Builds on 16 of its 34 references that are in the map. First posted on arXiv 5 Mar 2021.
Builds on
16 of 34 references.
References · 16
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,713
- 2015Distilling the Knowledge in a Neural Networkcited by 10,324
- 2014Explaining and Harnessing Adversarial Examplescited by 7,364
- 2018Co-teaching: Robust Training of Deep Neural Networks with Extremely Noisy Labelscited by 1,059
- 2018Generalized Cross Entropy Loss for Training Deep Neural Networks with Noisy Labelscited by 997
- 2017MentorNet: Learning Data-Driven Curriculum for Very Deep Neural Networks on Corrupted Labelscited by 653
- 2020Learning from Noisy Labels with Deep Neural Networks: A Surveycited by 582
- 2017Regularizing Neural Networks by Penalizing Confident Output Distributionscited by 464
- 2017Robust Loss Functions under Label Noise for Deep Neural Networkscited by 443
- 2018DUNet: A deformable network for retinal vessel segmentationcited by 90
- 2020SA-UNet: Spatial Attention U-Net for Retinal Vessel Segmentationcited by 71
- 2019IterNet: Retinal Image Segmentation Utilizing Structural Redundancy in Vessel Networkscited by 57
4 more
- 2018LadderNet: Multi-path networks based on U-Net for medical image segmentationcited by 29
- 2020An Elastic Interaction-Based Loss Function for Medical Image Segmentationcited by 9
- 2020Boosting Connectivity in Retinal Vessel Segmentation via a Recursive Semantics-Guided Networkcited by 5
- 2020Retinal Image Segmentation with a Structure-Texture Demixing Networkcited by 1
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Citing papers per year: 2021: 1; 2022: 1; 2023: 6; 2024: 5; 2025: 3; 2026: 4.
20 papers.
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- 2023HQG-Net: Unpaired Medical Image Enhancement with High-Quality Guidancecited by 36
- 2023DIAS: A Dataset and Benchmark for Intracranial Artery Segmentation in DSA sequencescited by 10
- 2025NTIRE 2025 challenge on Text to Image Generation Model Quality Assessmentcited by 8
- 2023RSF-Conv: Rotation-and-Scale Equivariant Fourier Parameterized Convolution for Retinal Vessel Segmentationcited by 5
- 2024TPOT: Topology Preserving Optimal Transport in Retinal Fundus Image Enhancementcited by 4
- 2022Semantic decomposition Network with Contrastive and Structural Constraints for Dental Plaque Segmentationcited by 2
- 2023SCOPE: Structural Continuity Preservation for Medical Image Segmentationcited by 2
- 2023FS-Net: Full Scale Network and Adaptive Threshold for Improving Extraction of Micro-Retinal Vessel Structurescited by 2
- 2024Benchmarking Retinal Blood Vessel Segmentation Models for Cross-Dataset and Cross-Disease Generalizationcited by 2
- 2021Attention W-Net: Improved Skip Connections for better Representationscited by 1
- 2024Convolutional Prompting for Broad-Domain Retinal Vessel Segmentationcited by 1
- 2025Deep Learning for Ophthalmology: The State-of-the-Art and Future Trendscited by 1
8 more
- 2023Logarithmic Mathematical Morphology: Theory and applicationscited by 0
- 2024A better approach to diagnose retinal diseases: Combining our Segmentation-based Vascular Enhancement with deep learning featurescited by 0
- 2024Conformable Convolution for Topologically Aware Learning of Complex Anatomical Structurescited by 0
- 2025VAOT: Vessel-Aware Optimal Transport for Retinal Fundus Enhancementcited by 0
- 2026Unsupervised Domain Adaptation with Target-Only Margin Disparity Discrepancycited by 0
- 2026Bridging Restoration and Diagnosis: A Comprehensive Benchmark for Retinal Fundus Enhancementcited by 0
- 2026Decoupled Single-Mask Annotation Noise Detection via Cross-Sectional Patch Self-Consistencycited by 0
- 2026Observer Choice and Threshold Selection in Retinal Vessel Segmentation: A Subject-Separated Evaluationcited by 0
- 2026Observer Choice and Threshold Selection in Retinal Vessel Segmentation: A Subject-Separated Evaluation22 Sep 2026
- 2026Decoupled Single-Mask Annotation Noise Detection via Cross-Sectional Patch Self-Consistency7 Jul 2026
- 2026Bridging Restoration and Diagnosis: A Comprehensive Benchmark for Retinal Fundus Enhancement4 Apr 2026
- 2026Unsupervised Domain Adaptation with Target-Only Margin Disparity Discrepancy10 Mar 2026
- 2025VAOT: Vessel-Aware Optimal Transport for Retinal Fundus Enhancement24 Nov 2025
- 2025NTIRE 2025 challenge on Text to Image Generation Model Quality Assessment22 May 2025
- 2025Deep Learning for Ophthalmology: The State-of-the-Art and Future Trends7 Jan 2025
- 2024Conformable Convolution for Topologically Aware Learning of Complex Anatomical Structures29 Dec 2024
- 2024Convolutional Prompting for Broad-Domain Retinal Vessel Segmentation24 Dec 2024
- 2024TPOT: Topology Preserving Optimal Transport in Retinal Fundus Image Enhancement3 Nov 2024
- 2024Benchmarking Retinal Blood Vessel Segmentation Models for Cross-Dataset and Cross-Disease Generalization21 Jun 2024
- 2024A better approach to diagnose retinal diseases: Combining our Segmentation-based Vascular Enhancement with deep learning features25 May 2024
8 more
- 2023FS-Net: Full Scale Network and Adaptive Threshold for Improving Extraction of Micro-Retinal Vessel Structures14 Nov 2023
- 2023RSF-Conv: Rotation-and-Scale Equivariant Fourier Parameterized Convolution for Retinal Vessel Segmentation27 Sep 2023
- 2023Logarithmic Mathematical Morphology: Theory and applications5 Sep 2023
- 2023HQG-Net: Unpaired Medical Image Enhancement with High-Quality Guidance15 Jul 2023
- 2023DIAS: A Dataset and Benchmark for Intracranial Artery Segmentation in DSA sequences21 Jun 2023
- 2023SCOPE: Structural Continuity Preservation for Medical Image Segmentation28 Apr 2023
- 2022Semantic decomposition Network with Contrastive and Structural Constraints for Dental Plaque Segmentation12 Aug 2022
- 2021Attention W-Net: Improved Skip Connections for better Representations17 Oct 2021
- 2023HQG-Net: Unpaired Medical Image Enhancement with High-Quality Guidancecited by 36
- 2023DIAS: A Dataset and Benchmark for Intracranial Artery Segmentation in DSA sequencescited by 10
- 2025NTIRE 2025 challenge on Text to Image Generation Model Quality Assessmentcited by 8
- 2023RSF-Conv: Rotation-and-Scale Equivariant Fourier Parameterized Convolution for Retinal Vessel Segmentationcited by 5
- 2024TPOT: Topology Preserving Optimal Transport in Retinal Fundus Image Enhancementcited by 4
- 2022Semantic decomposition Network with Contrastive and Structural Constraints for Dental Plaque Segmentationcited by 2
- 2023SCOPE: Structural Continuity Preservation for Medical Image Segmentationcited by 2
- 2023FS-Net: Full Scale Network and Adaptive Threshold for Improving Extraction of Micro-Retinal Vessel Structurescited by 2
- 2024Benchmarking Retinal Blood Vessel Segmentation Models for Cross-Dataset and Cross-Disease Generalizationcited by 2
- 2021Attention W-Net: Improved Skip Connections for better Representationscited by 1
- 2024Convolutional Prompting for Broad-Domain Retinal Vessel Segmentationcited by 1
- 2025Deep Learning for Ophthalmology: The State-of-the-Art and Future Trendscited by 1
12 most cited of 20 All 20 (JSON)
- 2026Observer Choice and Threshold Selection in Retinal Vessel Segmentation: A Subject-Separated Evaluation22 Sep 2026
- 2026Decoupled Single-Mask Annotation Noise Detection via Cross-Sectional Patch Self-Consistency7 Jul 2026
- 2026Bridging Restoration and Diagnosis: A Comprehensive Benchmark for Retinal Fundus Enhancement4 Apr 2026
- 2026Unsupervised Domain Adaptation with Target-Only Margin Disparity Discrepancy10 Mar 2026
- 2025VAOT: Vessel-Aware Optimal Transport for Retinal Fundus Enhancement24 Nov 2025
- 2025NTIRE 2025 challenge on Text to Image Generation Model Quality Assessment22 May 2025
- 2025Deep Learning for Ophthalmology: The State-of-the-Art and Future Trends7 Jan 2025
- 2024Conformable Convolution for Topologically Aware Learning of Complex Anatomical Structures29 Dec 2024
- 2024Convolutional Prompting for Broad-Domain Retinal Vessel Segmentation24 Dec 2024
- 2024TPOT: Topology Preserving Optimal Transport in Retinal Fundus Image Enhancement3 Nov 2024
- 2024Benchmarking Retinal Blood Vessel Segmentation Models for Cross-Dataset and Cross-Disease Generalization21 Jun 2024
- 2024A better approach to diagnose retinal diseases: Combining our Segmentation-based Vascular Enhancement with deep learning features25 May 2024
12 newest of 20 All 20 (JSON)