Interpretable and Steerable Sequence Learning via Prototypes
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Abstract (arXiv)
One of the major challenges in machine learning nowadays is to provide predictions with not only high accuracy but also user-friendly explanations. Although in recent years we have witnessed increasingly popular use of deep neural networks for sequence modeling, it is still challenging to explain the rationales behind the model outputs, which is essential for building trust and supporting the domain experts to validate, critique and refine the model. We propose ProSeNet, an interpretable and steerable deep sequence model with natural explanations derived from case-based reasoning. The prediction is obtained by comparing the inputs to a few prototypes, which are exemplar cases in the problem domain. For better interpretability, we define several criteria for constructing the prototypes, including simplicity, diversity, and sparsity and propose the learning objective and the optimization procedure. ProSeNet also provides a user-friendly approach to model steering: domain experts without any knowledge on the underlying model or parameters can easily incorporate their intuition and experience by manually refining the prototypes. We conduct experiments on a wide range of real-world applications, including predictive diagnostics for automobiles, ECG, and protein sequence classification and sentiment analysis on texts. The result shows that ProSeNet can achieve accuracy on par with state-of-the-art deep learning models. We also evaluate the interpretability of the results with concrete case studies. Finally, through user study on Amazon Mechanical Turk (MTurk), we demonstrate that the model selects high-quality prototypes which align well with human knowledge and can be interactively refined for better interpretability without loss of performance.
Key facts. Cited by 72 papers in the map (data through 7 Oct 2026). First posted on arXiv 23 Jul 2019.
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Citing papers per year: 2021: 12; 2022: 16; 2023: 11; 2024: 12; 2025: 16; 2026: 5.
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- 2021Interpretable Machine Learning: Fundamental Principles and 10 Grand Challengescited by 364
- 2022From Anecdotal Evidence to Quantitative Evaluation Methods: A Systematic Review on Evaluating Explainable AIcited by 299
- 2021Interpretable Deep Learning: Interpretation, Interpretability, Trustworthiness, and Beyondcited by 116
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- 2021This Looks Like That... Does it? Shortcomings of Latent Space Prototype Interpretability in Deep Networkscited by 65
- 2022Visual Recognition with Deep Nearest Centroidscited by 59
- 2021Explanation-Based Human Debugging of NLP Models: A Surveycited by 53
- 2022Concept-level Debugging of Part-Prototype Networkscited by 52
- 2025TimeXL: Explainable Multi-modal Time Series Prediction with LLM-in-the-Loopcited by 39
- 2023ProtoSeg: Interpretable Semantic Segmentation with Prototypical Partscited by 33
- 2022The State of the Art in Enhancing Trust in Machine Learning Models with the Use of Visualizationscited by 29
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- 2022This Patient Looks Like That Patient: Prototypical Networks for Interpretable Diagnosis Prediction from Clinical Textcited by 6
- 2023ProtoExplorer: Interpretable Forensic Analysis of Deepfake Videos using Prototype Exploration and Refinementcited by 5
- 2024Language Model Meets Prototypes: Towards Interpretable Text Classification Models through Prototypical Networkscited by 5
- 2021Interactively Providing Explanations for Transformer Language Modelscited by 4
- 2022ProtoX: Explaining a Reinforcement Learning Agent via Prototypingcited by 4
- 2022Learning to Select Prototypical Parts for Interpretable Sequential Data Modelingcited by 4
- 2023Prototypes as Explanation for Time Series Anomaly Detectioncited by 4
- 2024Multi-Scale Grouped Prototypes for Interpretable Semantic Segmentationcited by 4
- 2024GAProtoNet: A Multi-head Graph Attention-based Prototypical Network for Interpretable Text Classificationcited by 4
- 2025ProtoECGNet: Case-Based Interpretable Deep Learning for Multi-Label ECG Classification with Contrastive Learningcited by 4
- 2025From GNNs to Trees: Multi-Granular Interpretability for Graph Neural Networkscited by 4
- 2023Robust Text Classification: Analyzing Prototype-Based Networkscited by 3
- 2024Prototype-Based Methods in Explainable AI and Emerging Opportunities in the Geosciencescited by 3
- 2025Learning to Explain: Prototype-Based Surrogate Models for LLM Classificationcited by 3
- 2022NeuroView-RNN: It's About Timecited by 2
- 2022Care for the Mind Amid Chronic Diseases: An Interpretable AI Approach Using IoTcited by 2
- 2023PROMINET: Prototype-based Multi-View Network for Interpretable Email Response Predictioncited by 2
- 2023This Reads Like That: Deep Learning for Interpretable Natural Language Processingcited by 2
- 2024ProtoNAM: Prototypical Neural Additive Models for Interpretable Deep Tabular Learningcited by 2
- 2024Advancing Interpretability in Text Classification through Prototype Learningcited by 2
- 2024Regulation of Language Models With Interpretability Will Likely Result In A Performance Trade-Offcited by 2
50 most cited of 72 All 72 (JSON)
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- 2026Coupling Local Context and Global Semantic Prototypes via a Hierarchical Architecture for Rhetorical Roles Labeling4 Mar 2026
- 2026Prototype-based Explainable Neural Networks with Channel-specific Reasoning for Geospatial Learning Tasks30 Jan 2026
- 2025When, How Long and How Much? Interpretable Neural Networks for Time Series Regression by Learning to Mask and Aggregate3 Dec 2025
- 2025ProtoTSNet: Interpretable Multivariate Time Series Classification With Prototypical Parts4 Nov 2025
- 2025ProtoTopic: Prototypical Network for Few-Shot Medical Topic Modeling15 Oct 2025
- 2025ProtoSiTex: Learning Semi-Interpretable Prototypes for Multi-label Text Classification14 Oct 2025
- 2025Think as a Doctor: An Interpretable AI Approach for ICU Mortality Prediction11 Oct 2025
- 2025ProtoTS: Learning Hierarchical Prototypes for Explainable Time Series Forecasting27 Sep 2025
- 2025Fraud is Not Just Rarity: A Causal Prototype Attention Approach to Realistic Synthetic Oversampling19 Jul 2025
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- 2025Learning to Explain: Prototype-Based Surrogate Models for LLM Classification25 May 2025
- 2025From GNNs to Trees: Multi-Granular Interpretability for Graph Neural Networks1 May 2025
- 2025Leveraging multimodal explanatory annotations for video interpretation with Modality Specific Dataset15 Apr 2025
- 2025ProtoECGNet: Case-Based Interpretable Deep Learning for Multi-Label ECG Classification with Contrastive Learning11 Apr 2025
- 2025Patronus: Interpretable Diffusion Models with Prototypes28 Mar 2025
- 2025Enhancing Job Salary Prediction with Disentangled Composition Effect Modeling: A Neural Prototyping Approach17 Mar 2025
- 2025TimeXL: Explainable Multi-modal Time Series Prediction with LLM-in-the-Loop2 Mar 2025
- 2025A Comprehensive Survey on Self-Interpretable Neural Networks26 Jan 2025
- 2024Regulation of Language Models With Interpretability Will Likely Result In A Performance Trade-Off12 Dec 2024
- 2024Language Model Meets Prototypes: Towards Interpretable Text Classification Models through Prototypical Networks4 Dec 2024
- 2024Advancing Interpretability in Text Classification through Prototype Learning23 Oct 2024
- 2024Prototype-Based Methods in Explainable AI and Emerging Opportunities in the Geosciences22 Oct 2024
- 2024ProtoNAM: Prototypical Neural Additive Models for Interpretable Deep Tabular Learning7 Oct 2024
- 2024GAProtoNet: A Multi-head Graph Attention-based Prototypical Network for Interpretable Text Classification20 Sep 2024
- 2024Multi-Scale Grouped Prototypes for Interpretable Semantic Segmentation14 Sep 2024
- 2024MulCPred: Learning Multi-modal Concepts for Explainable Pedestrian Action Prediction14 Sep 2024
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- 2024Large Language Models are Interpretable Learners25 Jun 2024
- 2024Prototypical Reward Network for Data-Efficient RLHF6 Jun 2024
- 2024Explainable Predictive Maintenance: A Survey of Current Methods, Challenges and Opportunities15 Jan 2024
- 2023Robust Text Classification: Analyzing Prototype-Based Networks11 Nov 2023
- 2023Human-Guided Complexity-Controlled Abstractions26 Oct 2023
- 2023This Reads Like That: Deep Learning for Interpretable Natural Language Processing25 Oct 2023
- 2023PROMINET: Prototype-based Multi-View Network for Interpretable Email Response Prediction25 Oct 2023
- 2023Pixel-Grounded Prototypical Part Networks25 Sep 2023
- 2023ProtoExplorer: Interpretable Forensic Analysis of Deepfake Videos using Prototype Exploration and Refinement20 Sep 2023
- 2023Natural Example-Based Explainability: a Survey5 Sep 2023
- 2023Prototypes as Explanation for Time Series Anomaly Detection4 Jul 2023
- 2023ShuttleSet: A Human-Annotated Stroke-Level Singles Dataset for Badminton Tactical Analysis8 Jun 2023
- 2023ICICLE: Interpretable Class Incremental Continual Learning14 Mar 2023
- 2023ProtoSeg: Interpretable Semantic Segmentation with Prototypical Parts28 Jan 2023
- 2022The State of the Art in Enhancing Trust in Machine Learning Models with the Use of Visualizations22 Dec 2022
- 2022Learning to Select Prototypical Parts for Interpretable Sequential Data Modeling7 Dec 2022
- 2022Prototypical Fine-tuning: Towards Robust Performance Under Varying Data Sizes24 Nov 2022
- 2022Care for the Mind Amid Chronic Diseases: An Interpretable AI Approach Using IoT8 Nov 2022
- 2022ProtoX: Explaining a Reinforcement Learning Agent via Prototyping6 Nov 2022
- 2022This Patient Looks Like That Patient: Prototypical Networks for Interpretable Diagnosis Prediction from Clinical Text16 Oct 2022
50 newest of 72 All 72 (JSON)
- 2024Prototypical Reward Network for Data-Efficient RLHFcited by 22
- 2024Prototypical Reward Network for Data-Efficient RLHF6 Jun 2024
- 2025Patronus: Interpretable Diffusion Models with Prototypescited by 0
- 2025Patronus: Interpretable Diffusion Models with Prototypes28 Mar 2025
- 2021Interpretable Machine Learning: Fundamental Principles and 10 Grand Challengescited by 364
- 2022From Anecdotal Evidence to Quantitative Evaluation Methods: A Systematic Review on Evaluating Explainable AIcited by 299
- 2021Interpretable Deep Learning: Interpretation, Interpretability, Trustworthiness, and Beyondcited by 116
- 2021Interpretable Image Classification with Differentiable Prototypes Assignmentcited by 97
- 2021ProtGNN: Towards Self-Explaining Graph Neural Networkscited by 96
- 2021This Looks Like That... Does it? Shortcomings of Latent Space Prototype Interpretability in Deep Networkscited by 65
- 2022Visual Recognition with Deep Nearest Centroidscited by 59
- 2021Explanation-Based Human Debugging of NLP Models: A Surveycited by 53
- 2022Concept-level Debugging of Part-Prototype Networkscited by 52
- 2025TimeXL: Explainable Multi-modal Time Series Prediction with LLM-in-the-Loopcited by 39
- 2023ProtoSeg: Interpretable Semantic Segmentation with Prototypical Partscited by 33
- 2022The State of the Art in Enhancing Trust in Machine Learning Models with the Use of Visualizationscited by 29
12 most cited of 69 All 69 (JSON)
- 2026Information Bottleneck Learning for Faithful Time Series Forecasting Explanations30 Jul 2026
- 2026INSIGHTS: Demonstration-Based Summaries of Time Series Predictors13 May 2026
- 2026Coupling Local Context and Global Semantic Prototypes via a Hierarchical Architecture for Rhetorical Roles Labeling4 Mar 2026
- 2026Prototype-based Explainable Neural Networks with Channel-specific Reasoning for Geospatial Learning Tasks30 Jan 2026
- 2025When, How Long and How Much? Interpretable Neural Networks for Time Series Regression by Learning to Mask and Aggregate3 Dec 2025
- 2025ProtoTSNet: Interpretable Multivariate Time Series Classification With Prototypical Parts4 Nov 2025
- 2025ProtoTopic: Prototypical Network for Few-Shot Medical Topic Modeling15 Oct 2025
- 2025ProtoSiTex: Learning Semi-Interpretable Prototypes for Multi-label Text Classification14 Oct 2025
- 2025Think as a Doctor: An Interpretable AI Approach for ICU Mortality Prediction11 Oct 2025
- 2025ProtoTS: Learning Hierarchical Prototypes for Explainable Time Series Forecasting27 Sep 2025
- 2025Fraud is Not Just Rarity: A Causal Prototype Attention Approach to Realistic Synthetic Oversampling19 Jul 2025
- 2025Comprehensive Evaluation of Prototype Neural Networks9 Jul 2025
12 newest of 69 All 69 (JSON)