mlsanityData to 14 Oct 2026

CARE-X: Towards Clinically Useful Radiology VLMs with Auxiliary Supervision, Reward-Aligned Learning, and Tool-Augmented Measurement

arXiv 2608.03890 ↗First posted 4 Aug 2026cs.CV cs.AIcited by 0

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Abstract (arXiv)

A clinically useful chest X-ray system must go beyond fluent report generation: it should classify findings with tunable decision thresholds, localize them spatially, and derive the anatomical measurements upon which many diagnoses depend. Today's Vision-Language Models (VLMs) treat these as separate problems, if they address them at all, leaving a gap between what radiologists need and what generative models provide. We introduce CARE-X, a chest X-ray VLM that narrows this gap by unifying auxiliary discriminative supervision with reward-aligned generation. CARE-X augments its generative backbone with focal-loss classification and composite-loss grounding heads, co-trained alongside the language-modeling objective. This auxiliary supervision produces discriminative diagnostic predictions with tunable decision thresholds and precise spatial localization while also improving report quality, providing evidence that structured prediction and generation reinforce one another. Building on this foundation, Decoupled Clip and Dynamic Sampling Policy Optimization (DAPO) leverages task-specific reward signals for report generation, visual question answering (VQA), and spatial grounding, directly optimizing the clinical quality metrics that matter in practice. The result is state-of-the-art performance on the majority of metrics across four report-generation benchmarks, 94.0% VQA accuracy on ReXVQA (+6.0 pp over the next-best baseline), and generative spatial decoding that reaches near parity with dedicated detection heads. Separately, to address measurement-dependent diagnoses, we couple Qwen3-VL-4B-Instruct with native tool-calling capabilities for invoking deterministic measurement tools, while retaining full visual access to the image. This hybrid inference yields +43.6 pp average F1 over perception-only baselines across five measurement-dependent conditions.

Key facts. No citing papers in the map yet (data through 14 Oct 2026). Builds on 25 of its 33 references that are in the map. First posted on arXiv 4 Aug 2026.

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References · 25

  1. 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,380
  2. 2024DeepSeekMath: Pushing the Limits of Mathematical Reasoning in Open Language Modelscited by 9,379
  3. 2019BERTScore: Evaluating Text Generation with BERTcited by 5,512
  4. 2025Qwen3-VL Technical Reportcited by 2,793
  5. 2019CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparisoncited by 1,423
  6. 2017ChestX-ray8: Hospital-scale Chest X-ray Database and Benchmarks on Weakly-Supervised Classification and Localization of Common Thorax Diseasescited by 972
  7. 2019MIMIC-CXR-JPG, a large publicly available database of labeled chest radiographscited by 597
  8. 2025MedGemma Technical Reportcited by 436
  9. 2019PadChest: A large chest x-ray image dataset with multi-label annotated reportscited by 309
  10. 2020VinDr-CXR: An open dataset of chest X-rays with radiologist's annotationscited by 239
  11. 2024GREEN: Generative Radiology Report Evaluation and Error Notationcited by 128
  12. 2021Chest ImaGenome Dataset for Clinical Reasoningcited by 90
13 more
  1. 2022Improving the Factual Correctness of Radiology Report Generation with Semantic Rewardscited by 83
  2. 2020BIMCV COVID-19+: a large annotated dataset of RX and CT images from COVID-19 patientscited by 82
  3. 2025ReXGradient-160K: A Large-Scale Publicly Available Dataset of Chest Radiographs with Free-text Reportscited by 27
  4. 2022Detailed Annotations of Chest X-Rays via CT Projection for Report Understandingcited by 26
  5. 2023Accurate Fine-Grained Segmentation of Human Anatomy in Radiographs via Volumetric Pseudo-Labelingcited by 26
  6. 2024ReXrank: A Public Leaderboard for AI-Powered Radiology Report Generationcited by 25
  7. 2024Overview of the First Shared Task on Clinical Text Generation: RRG24 and "Discharge Me!"cited by 20
  8. 2025ReXVQA: A Large-scale Visual Question Answering Benchmark for Generalist Chest X-ray Understandingcited by 20
  9. 2026Scaling medical imaging report generation with multimodal reinforcement learningcited by 9
  10. 2026CRIMSON: A Clinically-Grounded LLM-Based Metric for Generative Radiology Report Evaluationcited by 9
  11. 2025CXReasonBench: A Benchmark for Evaluating Structured Diagnostic Reasoning in Chest X-rayscited by 6
  12. 2026A Reasoning-Enabled Vision-Language Foundation Model for Chest X-ray Interpretationcited by 5
  13. 2026CXReasonAgent: Evidence-Grounded Diagnostic Reasoning Agent for Chest X-rayscited by 3

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  1. 2026DobicVLM: Aligning Chest X-Ray Report Generation with Clinically-Grounded Programmatic Rewards via Group Relative Policy Optimization
  2. 2025Enhancing Radiology Report Generation and Visual Grounding using Reinforcement Learning
  3. 2026CXRMate-2: Structured Multimodal Temporal Embeddings and Tractable Reinforcement Learning for Clinically Acceptable Chest X-ray Radiology Report Generation
  4. 2024CheXalign: Preference fine-tuning in chest X-ray interpretation models without human feedback
  5. 2023Longitudinal Data and a Semantic Similarity Reward for Chest X-Ray Report Generation
  6. 2026Positive-Unlabeled Preference Optimization For Chest X-ray Report Generation
  7. 2025CheXPO: Preference Optimization for Chest X-ray VLMs with Counterfactual Rationale
  8. 2026Seeing Like Radiologists: Context- and Gaze-Guided Vision-Language Pretraining for Chest X-rays