mlsanityData to 14 Oct 2026

MedDDC-Eval: Diagnosis-Decoupled Evaluation of Multi-Turn Medical Consultation Agents

arXiv 2607.18999 ↗First posted 21 Jul 2026cs.CL cs.AIcited by 0

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Abstract (arXiv)

Evaluating multi-turn medical consultation agents requires judging the diagnostic support provided by the histories they elicit through interaction. Yet coupled evaluation lets each policy both elicit the history and generate the terminal diagnosis, so a diagnosis score confounds the elicited history with the policy's own terminal diagnosis generator. We introduce MedDDC-Eval, a diagnosis-decoupled evaluation testbed over held-out cases derived from medical records and online consultations. It applies the same frozen shared diagnostic reader to every policy-elicited history, holding terminal diagnosis generation fixed across policies and enabling comparison under the shared diagnostic reader. It reports diagnostic support, information-acquisition coverage, and efficiency. LLM-assisted semantic matching followed by deterministic one-to-one assignment makes the diagnosis-trajectory-efficiency (D/T/E) scores auditable. In a fixed-history audit across eight policies, replacing each policy's own generator with the shared diagnostic reader shifts diagnosis F1 by 2.2-19.0 points and reverses 18% and 36% of pairwise orderings on the Record and Dialogue splits. To examine downstream utility, we use standard Group Relative Policy Optimization (GRPO) with a separate training-time reward that targets the same diagnosis and trajectory dimensions. Relative to its Qwen3-32B initialization, the trained policy gains 9.6 and 4.6 aggregate-score points on the held-out Record and Dialogue splits, respectively, and ablating either feedback signal reduces the aggregate score on both. Together, MedDDC-Eval supports comparison under a shared diagnostic reader and evaluation-informed policy development, while complementing end-to-end evaluation when terminal diagnosis generation is also part of the target capability.

Key facts. No citing papers in the map yet (data through 14 Oct 2026). Builds on 25 of its 29 references that are in the map. First posted on arXiv 21 Jul 2026.

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References · 25

  1. 2024DeepSeekMath: Pushing the Limits of Mathematical Reasoning in Open Language Modelscited by 9,379
  2. 2025Qwen3 Technical Reportcited by 8,820
  3. 2025DAPO: An Open-Source LLM Reinforcement Learning System at Scalecited by 2,810
  4. 2022Large Language Models Encode Clinical Knowledgecited by 1,830
  5. 2025Understanding R1-Zero-Like Training: A Critical Perspectivecited by 1,345
  6. 2025Group-in-Group Policy Optimization for LLM Agent Trainingcited by 497
  7. 2024HuatuoGPT-o1, Towards Medical Complex Reasoning with LLMscited by 265
  8. 2024AgentClinic: a multimodal agent benchmark to evaluate AI in simulated clinical environmentscited by 231
  9. 2022DDXPlus: A New Dataset For Automatic Medical Diagnosiscited by 88
  10. 2025Reinforcing Multi-Turn Reasoning in LLM Agents via Fine-Grained Reward Structure and Credit Assignmentcited by 79
  11. 2024UltraMedical: Building Specialized Generalists in Biomedicinecited by 67
  12. 2025MedHELM: Holistic Evaluation of Large Language Models for Medical Taskscited by 64
13 more
  1. 2025MedAgentBench: A Realistic Virtual EHR Environment to Benchmark Medical LLM Agentscited by 62
  2. 2025AgentRL: Scaling Agentic Reinforcement Learning with a Multi-Turn, Multi-Task Frameworkcited by 62
  3. 2025Turn-PPO: Turn-Level Advantage Estimation with PPO for Improved Multi-Turn RL in Agentic LLMscited by 30
  4. 2025FHIR-AgentBench: Benchmarking LLM Agents for Realistic Interoperable EHR Question Answeringcited by 22
  5. 2026PhysicianBench: Evaluating LLM Agents in Real-World EHR Environmentscited by 21
  6. 2025Doctor-R1: Mastering Clinical Inquiry with Experiential Agentic Reinforcement Learningcited by 14
  7. 2025MedBench v4: A Robust and Scalable Benchmark for Evaluating Chinese Medical Language Models, Multimodal Models, and Intelligent Agentscited by 8
  8. 2026TSR: Trajectory-Search Rollouts for Multi-Turn RL of LLM Agentscited by 7
  9. 2026EHR-Complex: Benchmarking Medical Agents for Complex Clinical Reasoningcited by 5
  10. 2026MedConsultBench: A Full-Cycle, Fine-Grained, Process-Aware Benchmark for Medical Consultation Agentscited by 4
  11. 2026MeDxAgent: Multi-Agent Consultation for Interactive Medical Diagnosiscited by 4
  12. 2026Beyond Idealized Patients: Evaluating LLMs under Challenging Patient Behaviors in Medical Consultationscited by 3
  13. 2026ThReadMed-QA: A Multi-Turn Medical Dialogue Benchmark from Real Patient Questionscited by 1

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