MedBench v4: A Robust and Scalable Benchmark for Evaluating Chinese Medical Language Models, Multimodal Models, and Intelligent Agents
On the map: LLM agents and tool use → Medical and scientific domain agents
Abstract (arXiv)
Recent advances in medical large language models (LLMs), multimodal models, and agents demand evaluation frameworks that reflect real clinical workflows and safety constraints. We present MedBench v4, a nationwide, cloud-based benchmarking infrastructure comprising over 700,000 expert-curated tasks spanning 24 primary and 91 secondary specialties, with dedicated tracks for LLMs, multimodal models, and agents. Items undergo multi-stage refinement and multi-round review by clinicians from more than 500 institutions, and open-ended responses are scored by an LLM-as-a-judge calibrated to human ratings. We evaluate 15 frontier models. Base LLMs reach a mean overall score of 54.1/100 (best: Claude Sonnet 4.5, 62.5/100), but safety and ethics remain low (18.4/100). Multimodal models perform worse overall (mean 47.5/100; best: GPT-5, 54.9/100), with solid perception yet weaker cross-modal reasoning. Agents built on the same backbones substantially improve end-to-end performance (mean 79.8/100), with Claude Sonnet 4.5-based agents achieving up to 85.3/100 overall and 88.9/100 on safety tasks. MedBench v4 thus reveals persisting gaps in multimodal reasoning and safety for base models, while showing that governance-aware agentic orchestration can markedly enhance benchmarked clinical readiness without sacrificing capability. By aligning tasks with Chinese clinical guidelines and regulatory priorities, the platform offers a practical reference for hospitals, developers, and policymakers auditing medical AI.
Key facts. Cited by 8 papers in the map (data through 7 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 7 of its 27 references that are in the map. First posted on arXiv 18 Nov 2025.
Builds on
7 of 27 references.
References · 7
- 2022Large Language Models Encode Clinical Knowledgecited by 1,807
- 2021SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answeringcited by 444
- 2025HealthBench: Evaluating Large Language Models Towards Improved Human Healthcited by 385
- 2024Survey on Large Language Model-Enhanced Reinforcement Learning: Concept, Taxonomy, and Methodscited by 114
- 2021CBLUE: A Chinese Biomedical Language Understanding Evaluation Benchmarkcited by 99
- 2023Benchmarking Large Language Models on CMExam -- A Comprehensive Chinese Medical Exam Datasetcited by 90
- 2020Trust and Medical AI: The challenges we face and the expertise needed to overcome themcited by 21
Built on by
Citing papers per year: 2026: 8.
8 papers.
- 2026LongMedBench: Benchmarking Medical Agents for Long-Horizon Clinical Decision-Makingcited by 6
- 2026RadSEM: A Finding-by-Finding Metric for Clinical Consistency in Radiology Reportscited by 3
- 2026ProMedical: Hierarchical Fine-Grained Criteria Modeling for Medical LLM Alignment via Explicit Injectioncited by 2
- 2026ClinConsensus: A Physician-Calibrated Benchmark for Evaluating Clinical Rubric Coverage in Chinese Medical LLMscited by 0
- 2026DongYuan: An LLM-Based Framework for Integrative Chinese and Western Medicine Spleen-Stomach Disorders Diagnosiscited by 0
- 2026Toward Vibe Medicine: A Self-Evolving Multi-Agent Framework for Clinical Decision Supportcited by 0
- 2026MedRealMM: A Real-World Multimodal Benchmark for Chinese Online Medical Consultationcited by 0
- 2026MedDDC-Eval: Diagnosis-Decoupled Evaluation of Multi-Turn Medical Consultation Agentscited by 0
- 2026MedDDC-Eval: Diagnosis-Decoupled Evaluation of Multi-Turn Medical Consultation Agents21 Jul 2026
- 2026LongMedBench: Benchmarking Medical Agents for Long-Horizon Clinical Decision-Making10 Jul 2026
- 2026MedRealMM: A Real-World Multimodal Benchmark for Chinese Online Medical Consultation10 Jul 2026
- 2026RadSEM: A Finding-by-Finding Metric for Clinical Consistency in Radiology Reports3 Jun 2026
- 2026ProMedical: Hierarchical Fine-Grained Criteria Modeling for Medical LLM Alignment via Explicit Injection9 Apr 2026
- 2026Toward Vibe Medicine: A Self-Evolving Multi-Agent Framework for Clinical Decision Support1 Apr 2026
- 2026DongYuan: An LLM-Based Framework for Integrative Chinese and Western Medicine Spleen-Stomach Disorders Diagnosis30 Mar 2026
- 2026ClinConsensus: A Physician-Calibrated Benchmark for Evaluating Clinical Rubric Coverage in Chinese Medical LLMs2 Mar 2026
Similar, not cited
Close in wording, no citation either way
- 2023MedBench: A Large-Scale Chinese Benchmark for Evaluating Medical Large Language Models
- 2025Benchmarking Chinese Medical LLMs: A Medbench-based Analysis of Performance Gaps and Hierarchical Optimization Strategies
- 2025MTCMB: A Multi-Task Benchmark Framework for Evaluating LLMs on Knowledge, Reasoning, and Safety in Traditional Chinese Medicine
- 2025MedHELM: Holistic Evaluation of Large Language Models for Medical Tasks
- 2025Beyond the Leaderboard: Rethinking Medical Benchmarks for Large Language Models
- 2025MedAgentBench: A Realistic Virtual EHR Environment to Benchmark Medical LLM Agents
- 2025Automating Expert-Level Medical Reasoning Evaluation of Large Language Models
- 2025MedFact: Benchmarking the Fact-Checking Capabilities of Large Language Models on Chinese Medical Texts