mlsanityData to 7 Oct 2026

PATIENT-Psi: Using Large Language Models to Simulate Patients for Training Mental Health Professionals

arXiv 2405.19660 ↗First posted 30 May 2024cs.CLcited by 19

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Abstract (arXiv)

Mental illness remains one of the most critical public health issues. Despite its importance, many mental health professionals highlight a disconnect between their training and actual real-world patient practice. To help bridge this gap, we propose PATIENT-Psi, a novel patient simulation framework for cognitive behavior therapy (CBT) training. To build PATIENT-Psi, we construct diverse patient cognitive models based on CBT principles and use large language models (LLMs) programmed with these cognitive models to act as a simulated therapy patient. We propose an interactive training scheme, PATIENT-Psi-TRAINER, for mental health trainees to practice a key skill in CBT -- formulating the cognitive model of the patient -- through role-playing a therapy session with PATIENT-Psi. To evaluate PATIENT-Psi, we conducted a comprehensive user study of 13 mental health trainees and 20 experts. The results demonstrate that practice using PATIENT-Psi-TRAINER enhances the perceived skill acquisition and confidence of the trainees beyond existing forms of training such as textbooks, videos, and role-play with non-patients. Based on the experts' perceptions, PATIENT-Psi is perceived to be closer to real patient interactions than GPT-4, and PATIENT-Psi-TRAINER holds strong promise to improve trainee competencies. Our code and data are released at urlhttps://github.com/ruiyiw/patient-psi.

Key facts. Cited by 19 papers in the map (data through 7 Oct 2026). Builds on 18 of its 59 references that are in the map. First posted on arXiv 30 May 2024.

Builds on

18 of 59 references.

References · 18

  1. 2023GPT-4 Technical Reportcited by 18,132
  2. 2023Sparks of Artificial General Intelligence: Early experiments with GPT-4cited by 2,579
  3. 2023Can Large Language Models Be an Alternative to Human Evaluations?cited by 729
  4. 2023Can Large Language Models Transform Computational Social Science?cited by 245
  5. 2020A Computational Approach to Understanding Empathy Expressed in Text-Based Mental Health Supportcited by 182
  6. 2021MentalBERT: Publicly Available Pretrained Language Models for Mental Healthcarecited by 159
  7. 2024SOTOPIA-π: Interactive Learning of Socially Intelligent Language Agentscited by 89
  8. 2023Cognitive Reframing of Negative Thoughts through Human-Language Model Interactioncited by 77
  9. 2024A Computational Framework for Behavioral Assessment of LLM Therapistscited by 61
  10. 2023Facilitating Self-Guided Mental Health Interventions Through Human-Language Model Interaction: A Case Study of Cognitive Restructuringcited by 53
  11. 2023CLASS: A Design Framework for building Intelligent Tutoring Systems based on Learning Science principlescited by 46
  12. 2023Empowering Psychotherapy with Large Language Models: Cognitive Distortion Detection through Diagnosis of Thought Promptingcited by 31
6 more
  1. 2023Enhancing Psychological Counseling with Large Language Model: A Multifaceted Decision-Support System for Non-Professionalscited by 24
  2. 2023Helping the Helper: Supporting Peer Counselors via AI-Empowered Practice and Feedbackcited by 23
  3. 2020Engagement Patterns of Peer-to-Peer Interactions on Mental Health Platformscited by 16
  4. 2024Social Skill Training with Large Language Modelscited by 13
  5. 2024IMBUE: Improving Interpersonal Effectiveness through Simulation and Just-in-time Feedback with Human-Language Model Interactioncited by 12
  6. 2022EmoMent: An Emotion Annotated Mental Health Corpus from two South Asian Countriescited by 7

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2024: 4; 2025: 13; 2026: 2.

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  1. 2025LLM Generated Persona is a Promise with a Catchcited by 77
  2. 2024TeachTune: Reviewing Pedagogical Agents Against Diverse Student Profiles with Simulated Studentscited by 25
  3. 2025EmoAgent: Assessing and Safeguarding Human-AI Interaction for Mental Health Safetycited by 21
  4. 2025Technological folie `a deux: Feedback Loops Between AI Chatbots and Mental Illnesscited by 14
  5. 2025MetaMind: Modeling Human Social Thoughts with Metacognitive Multi-Agent Systemscited by 12
  6. 2026MedDialogRubrics: A Comprehensive Benchmark and Evaluation Framework for Multi-turn Medical Consultations in Large Language Modelscited by 12
  7. 2025MindEval: Benchmarking Language Models on Multi-turn Mental Health Supportcited by 9
  8. 2025How Strategic Agents Respond: Comparing Analytical Models with LLM-Generated Responses in Strategic Classificationcited by 4
  9. 2024MentalArena: Self-play Training of Language Models for Diagnosis and Treatment of Mental Health Disorderscited by 1
  10. 2024Quantifying Risk Propensities of Large Language Models: Ethical Focus and Bias Detection through Role-Playcited by 1
  11. 2025Free Lunch for User Experience: Crowdsourcing Agents for Scalable User Studiescited by 1
  12. 2025DS@GT at eRisk 2025: From prompts to predictions, benchmarking early depression detection with conversational agent based assessments and temporal attention modelscited by 1
7 more
  1. 2025From Medical Records to Diagnostic Dialogues: A Clinical-Grounded Approach and Dataset for Psychiatric Comorbiditycited by 1
  2. 2026TherapyGym: Evaluating and Aligning Clinical Fidelity and Safety in Therapy Chatbotscited by 1
  3. 2024An LLM-based Simulation Framework for Embodied Conversational Agents in Psychological Counselingcited by 0
  4. 2025When and How to Integrate Multimodal Large Language Models in College Psychotherapy: Perspectives from Multi-stakeholderscited by 0
  5. 2025First, Do No Harm: AI Supervisor Scaffolds Novice Growth in Counselor Educationcited by 0
  6. 2025A Voice-Enabled Virtual Patient System for Interactive Training in Standardized Clinical Assessmentcited by 0
  7. 2025Can we use LLMs to bootstrap reinforcement learning? -- A case study in digital health behavior changecited by 0