AI Meets Brain: Memory Systems from Cognitive Neuroscience to Autonomous Agents
On the map: LLM agents and tool use → Agent memory systems
Abstract (arXiv)
Memory serves as the pivotal nexus bridging past and future, providing both humans and AI systems with invaluable concepts and experience to navigate complex tasks. Recent research on autonomous agents has increasingly focused on designing efficient memory workflows by drawing on cognitive neuroscience. However, constrained by interdisciplinary barriers, existing works struggle to assimilate the essence of human memory mechanisms. To bridge this gap, we systematically synthesizes interdisciplinary knowledge of memory, connecting insights from cognitive neuroscience with LLM-driven agents. Specifically, we first elucidate the definition and function of memory along a progressive trajectory from cognitive neuroscience through LLMs to agents. We then provide a comparative analysis of memory taxonomy, storage mechanisms, and the complete management lifecycle from both biological and artificial perspectives. Subsequently, we review the mainstream benchmarks for evaluating agent memory. Additionally, we explore memory security from dual perspectives of attack and defense. Finally, we envision future research directions, with a focus on multimodal memory systems and skill acquisition.
Key facts. Cited by 12 papers in the map (data through 7 Oct 2026). Placed in Agent memory systems, one of 16 directions in LLM agents and tool use. Builds on 172 of its 400 references that are in the map. First posted on arXiv 29 Dec 2025.
Builds on
172 of 400 references.
Closest ancestors · 51
Same direction, newest first
- 2025Memory in the Age of AI Agents15 Dec
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- 2025Evo-Memory: Benchmarking LLM Agent Test-time Learning with Self-Evolving Memory25 Nov
- 2025General Agentic Memory Via Deep Research23 Nov
- 2025A Benchmark for Procedural Memory Retrieval in Language Agents21 Nov
- 2025From Experience to Strategy: Empowering LLM Agents with Trainable Graph Memory11 Nov
- 2025LiCoMemory: Lightweight and Cognitive Agentic Memory for Efficient Long-Term Reasoning3 Nov
- 2025AgentFold: Long-Horizon Web Agents with Proactive Context Management28 Oct
- 2025Learning from Supervision with Semantic and Episodic Memory: A Reflective Approach to Agent Adaptation22 Oct
- 2025RGMem: Renormalization Group-inspired Memory Evolution for Language Agents18 Oct
- 2025AUGUSTUS: An LLM-Driven Multimodal Agent System with Contextualized User Memory17 Oct
- 2025Memory as Action: Autonomous Context Curation for Long-Horizon Agentic Tasks14 Oct
38 more
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- 2025Enabling Personalized Long-term Interactions in LLM-based Agents through Persistent Memory and User Profiles9 Oct
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- 2025CAM: A Constructivist View of Agentic Memory for LLM-Based Reading Comprehension7 Oct
- 2025LEGOMem: Modular Procedural Memory for Multi-agent LLM Systems for Workflow Automation6 Oct
- 2025Agentic Context Engineering: Evolving Contexts for Self-Improving Language Models6 Oct
- 2025ReasoningBank: Scaling Agent Self-Evolving with Reasoning Memory29 Sep
- 2025MemGen: Weaving Generative Latent Memory for Self-Evolving Agents29 Sep
- 2025SGMem: Sentence Graph Memory for Long-Term Conversational Agents25 Sep
- 2025ReSum: Unlocking Long-Horizon Search Intelligence via Context Summarization16 Sep
- 2025H2R: Hierarchical Hindsight Reflection for Multi-Task LLM Agents16 Sep
- 2025EgoMem: Lifelong Memory Agent for Full-duplex Omnimodal Models15 Sep
- 2025Text2Mem: A Unified Memory Operation Language for Memory Operating System14 Sep
- 2025Memory-R1: Enhancing Large Language Model Agents to Manage and Utilize Memories via Reinforcement Learning27 Aug
- 2025Memento: Fine-tuning LLM Agents without Fine-tuning LLMs22 Aug
- 2025Coarse-to-Fine Grounded Memory for LLM Agent Planning21 Aug
- 2025Explicit v.s. Implicit Memory: Exploring Multi-hop Complex Reasoning Over Personalized Information18 Aug
- 2025Learn to Memorize: Optimizing LLM-based Agents with Adaptive Memory Framework15 Aug
- 2025What Deserves Memory: Adaptive Memory Distillation for LLM Agents5 Aug
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- 2025Hierarchical Memory for High-Efficiency Long-Term Reasoning in LLM Agents23 Jul
- 2025Agent KB: Leveraging Cross-Domain Experience for Agentic Problem Solving8 Jul
- 2025Evaluating Memory in LLM Agents via Incremental Multi-Turn Interactions7 Jul
- 2025MEM1: Learning to Synergize Memory and Reasoning for Efficient Long-Horizon Agents18 Jun
- 2025G-Memory: Tracing Hierarchical Memory for Multi-Agent Systems9 Jun
- 2025PersonaAgent: Bridging Memory and Action for Personalized LLM Agents6 Jun
- 2025Memory OS of AI Agent30 May
- 2025MemGuide: Intent-Driven Memory Selection for Goal-Oriented Multi-Session LLM Agents26 May
- 2025From Single to Multi-Granularity: Toward Long-Term Memory Association and Selection of Conversational Agents26 May
- 2025Collaborative Memory: Multi-User Memory Sharing in LLM Agents with Dynamic Access Control23 May
- 2025CAIM: Development and Evaluation of a Cognitive AI Memory Framework for Long-Term Interaction with Intelligent Agents19 May
- 2025LifelongAgentBench: Evaluating LLM Agents as Lifelong Learners17 May
- 2025Mem0: Building Production-Ready AI Agents with Scalable Long-Term Memory28 Apr
- 2025A-MEM: Agentic Memory for LLM Agents17 Feb
- 2025Lifelong Learning of Large Language Model based Agents: A Roadmap13 Jan
- 2024MemSim: A Bayesian Simulator for Evaluating Memory of LLM-based Personal Assistants30 Sep
- 2024A Survey on the Memory Mechanism of Large Language Model based Agents21 Apr
- 2024INMS: Memory Sharing for Large Language Model based Agents15 Apr
50 newest of 51 All 51 (JSON)
Other references · 121
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- 2025SkillWeaver: Web Agents can Self-Improve by Discovering and Honing Skillscited by 174
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- 2025WebAgent-R1: Training Web Agents via End-to-End Multi-Turn Reinforcement Learningcited by 162
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- 2025xbench: Tracking Agents Productivity Scaling with Profession-Aligned Real-World Evaluationscited by 118
- 2024Large Multimodal Agents: A Surveycited by 99
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- 2025A Survey on Trustworthy LLM Agents: Threats and Countermeasurescited by 93
- 2024The rising costs of training frontier AI modelscited by 91
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- 2023Advancing Transformer Architecture in Long-Context Large Language Models: A Comprehensive Surveycited by 71
- 2025DeepAgent: A General Reasoning Agent with Scalable Toolsetscited by 69
- 2025SEAgent: Self-Evolving Computer Use Agent with Autonomous Learning from Experiencecited by 68
- 2025WebResearcher: Unleashing unbounded reasoning capability in Long-Horizon Agentscited by 66
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- 2025SWE-Exp: Experience-Driven Software Issue Resolutioncited by 64
- 2024TrojanRAG: Retrieval-Augmented Generation Can Be Backdoor Driver in Large Language Modelscited by 63
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- 2025HaluMem: Evaluating Hallucinations in Memory Systems of Agentscited by 51
- 2025FLEX: Continuous Agent Evolution via Forward Learning from Experiencecited by 51
- 2025WorldMM: Dynamic Multimodal Memory Agent for Long Video Reasoningcited by 50
50 most cited of 121 All 121 (JSON)
Built on by
Citing papers per year: 2026: 12.
12 papers.
- 2026A Survey of Agent Memory in the Second Half: Towards Self-Evolving and Long-Horizon Agentscited by 40
- 2026A Survey on Long-Term Memory Security in LLM Agents: Attacks, Defenses, and Governance Across the Memory Lifecyclecited by 21
- 2026Beyond Static Summarization: Proactive Memory Extraction for LLM Agentscited by 20
- 2026The Evolution of Tool Use in LLM Agents: From Single-Tool Call to Multi-Tool Orchestrationcited by 11
- 2026Fine-Mem: Fine-Grained Feedback Alignment for Long-Horizon Memory Managementcited by 8
- 2026HeLa-Mem: Hebbian Learning and Associative Memory for LLM Agentscited by 5
- 2026A Systematic Investigation of Document Chunking Strategies and Embedding Sensitivitycited by 3
- 2026Scaling Self-Evolving Agents via Parametric Memorycited by 3
- 2026M3Eval: Multi-Modal Memory Evaluation through Cognitively-Grounded Video Taskscited by 1
- 2026SRTJ: Self-Evolving Rule-Driven Training-Free LLM Jailbreakingcited by 0
- 2026OpenClaw and Ollama in Agentic AI: Toward Fully Autonomous and Scalable AI Agent Systemscited by 0
- 2026VeriPhy: Agentic Physical Reasoning for World Model Evaluation and Refinementcited by 0
- 2026VeriPhy: Agentic Physical Reasoning for World Model Evaluation and Refinement2 Sep 2026
- 2026M3Eval: Multi-Modal Memory Evaluation through Cognitively-Grounded Video Tasks3 Jun 2026
- 2026Scaling Self-Evolving Agents via Parametric Memory3 Jun 2026
- 2026SRTJ: Self-Evolving Rule-Driven Training-Free LLM Jailbreaking1 May 2026
- 2026HeLa-Mem: Hebbian Learning and Associative Memory for LLM Agents18 Apr 2026
- 2026A Survey on Long-Term Memory Security in LLM Agents: Attacks, Defenses, and Governance Across the Memory Lifecycle17 Apr 2026
- 2026OpenClaw and Ollama in Agentic AI: Toward Fully Autonomous and Scalable AI Agent Systems16 Apr 2026
- 2026The Evolution of Tool Use in LLM Agents: From Single-Tool Call to Multi-Tool Orchestration24 Mar 2026
- 2026A Systematic Investigation of Document Chunking Strategies and Embedding Sensitivity7 Mar 2026
- 2026A Survey of Agent Memory in the Second Half: Towards Self-Evolving and Long-Horizon Agents14 Jan 2026
- 2026Fine-Mem: Fine-Grained Feedback Alignment for Long-Horizon Memory Management13 Jan 2026
- 2026Beyond Static Summarization: Proactive Memory Extraction for LLM Agents8 Jan 2026
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