DentalGPT: Incentivizing Multimodal Complex Reasoning in Dentistry
On the map: LLM reasoning → Clinical and biomedical applications
Abstract (arXiv)
Reliable interpretation of multimodal data in dentistry is essential for automated oral healthcare, yet current multimodal large language models (MLLMs) struggle to capture fine-grained dental visual details and lack sufficient reasoning ability for precise diagnosis. To address these limitations, we present DentalGPT, a specialized dental MLLM developed through high-quality domain knowledge injection and reinforcement learning. Specifically, the largest annotated multimodal dataset for dentistry to date was constructed by aggregating over 120k dental images paired with detailed descriptions that highlight diagnostically relevant visual features, making it the multimodal dataset with the most extensive collection of dental images to date. Training on this dataset significantly enhances the MLLM's visual understanding of dental conditions, while the subsequent reinforcement learning stage further strengthens its capability for multimodal complex reasoning. Comprehensive evaluations on intraoral and panoramic benchmarks, along with dental subsets of medical VQA benchmarks, show that DentalGPT achieves superior performance in disease classification and dental VQA tasks, outperforming many state-of-the-art MLLMs despite having only 7B parameters. These results demonstrate that high-quality dental data combined with staged adaptation provides an effective pathway for building capable and domain-specialized dental MLLMs.
Key facts. Cited by 5 papers in the map (data through 7 Oct 2026). Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning. Builds on 35 of its 57 references that are in the map. First posted on arXiv 12 Dec 2025.
Builds on
35 of 57 references.
Closest ancestors · 6
Same direction, newest first
- 2025PathAgent: Toward Interpretable Analysis of Whole-slide Pathology Images via Large Language Model-based Agentic Reasoning21 Nov
- 2025Pathology-CoT: Learning Visual Chain-of-Thought Agent from Expert Whole Slide Image Diagnosis Behavior6 Oct
- 2025Lingshu: A Generalist Foundation Model for Unified Multimodal Medical Understanding and Reasoning8 Jun
- 2025GMAI-VL-R1: Harnessing Reinforcement Learning for Multimodal Medical Reasoning2 Apr
- 2025Med-RLVR: Emerging Medical Reasoning from a 3B base model via reinforcement Learning27 Feb
- 2024HuatuoGPT-o1, Towards Medical Complex Reasoning with LLMs25 Dec
Other references · 29
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- 2025DeepSeek-R1: Incentivizing Reasoning Capability in LLMs via Reinforcement Learningcited by 6,146
- 2025Qwen2.5-VL Technical Reportcited by 5,418
- 2025Gemini 2.5: Pushing the Frontier with Advanced Reasoning, Multimodality, Long Context, and Next Generation Agentic Capabilitiescited by 3,655
- 2025Qwen3-VL Technical Reportcited by 2,534
- 2025Gemma 3 Technical Reportcited by 1,686
- 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Daycited by 1,287
- 2024OpenAI o1 System Cardcited by 1,220
- 2023Gemini: A Family of Highly Capable Multimodal Modelscited by 810
- 2023OpenFlamingo: An Open-Source Framework for Training Large Autoregressive Vision-Language Modelscited by 560
- 2024DeepSeek-VL2: Mixture-of-Experts Vision-Language Models for Advanced Multimodal Understandingcited by 559
- 2025Phi-4-Mini Technical Report: Compact yet Powerful Multimodal Language Models via Mixture-of-LoRAscited by 491
17 more
- 2025GLM-4.5V and GLM-4.1V-Thinking: Towards Versatile Multimodal Reasoning with Scalable Reinforcement Learningcited by 439
- 2023PMC-VQA: Visual Instruction Tuning for Medical Visual Question Answeringcited by 333
- 2025MedXpertQA: Benchmarking Expert-Level Medical Reasoning and Understandingcited by 212
- 2024HuatuoGPT-Vision, Towards Injecting Medical Visual Knowledge into Multimodal LLMs at Scalecited by 194
- 2024OmniMedVQA: A New Large-Scale Comprehensive Evaluation Benchmark for Medical LVLMcited by 182
- 2023Towards Generalist Foundation Model for Radiology by Leveraging Web-scale 2D&3D Medical Datacited by 176
- 2025HealthGPT: A Medical Large Vision-Language Model for Unifying Comprehension and Generation via Heterogeneous Knowledge Adaptationcited by 112
- 2024MedTrinity-25M: A Large-scale Multimodal Dataset with Multigranular Annotations for Medicinecited by 79
- 2024ECG-Chat: A Large ECG-Language Model for Cardiac Disease Diagnosiscited by 37
- 2024Teach Multimodal LLMs to Comprehend Electrocardiographic Imagescited by 25
- 2025Towards Better Dental AI: A Multimodal Benchmark and Instruction Dataset for Panoramic X-ray Analysiscited by 16
- 2025DentVLM: A Multimodal Vision-Language Model for Comprehensive Dental Diagnosis and Enhanced Clinical Practicecited by 13
- 2025OralGPT-Omni: A Versatile Dental Multimodal Large Language Modelcited by 10
- 2025ShizhenGPT: Towards Multimodal LLMs for Traditional Chinese Medicinecited by 6
- 2025WaveMind: Towards a Conversational EEG Foundation Model Aligned to Textual and Visual Modalitiescited by 5
- 2025MedKGEval: A Knowledge Graph-Based Multi-Turn Evaluation Framework for Open-Ended Patient Interactions with Clinical LLMscited by 3
- 2025AlphaDent: A dataset for automated tooth pathology detectioncited by 2
Built on by
Citing papers per year: 2026: 5.
5 papers.
- 2026OPGAgent: An Agent for Auditable Dental Panoramic X-ray Interpretationcited by 4
- 2026OralGPT-Plus: Learning to Use Visual Tools via Reinforcement Learning for Panoramic X-ray Analysiscited by 4
- 2026OralAgent: Integrating Reasoning, Tools, and Knowledge for Interactive Dental Image Analysiscited by 3
- 2026IOSVLM: A 3D Vision-Language Model for Unified Dental Diagnosis from Intraoral Scanscited by 1
- 2026GlobalDentBench: A Multinational Benchmark for Evaluating LLM Clinical Reasoning in Dentistry with Expert Calibrationcited by 0
- 2026GlobalDentBench: A Multinational Benchmark for Evaluating LLM Clinical Reasoning in Dentistry with Expert Calibration23 May 2026
- 2026OralAgent: Integrating Reasoning, Tools, and Knowledge for Interactive Dental Image Analysis9 Apr 2026
- 2026IOSVLM: A 3D Vision-Language Model for Unified Dental Diagnosis from Intraoral Scans17 Mar 2026
- 2026OralGPT-Plus: Learning to Use Visual Tools via Reinforcement Learning for Panoramic X-ray Analysis6 Mar 2026
- 2026OPGAgent: An Agent for Auditable Dental Panoramic X-ray Interpretation28 Feb 2026
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