Seg4Diff: Unveiling Open-Vocabulary Segmentation in Text-to-Image Diffusion Transformers
On the map: Diffusion models → Medical imaging and segmentation
Abstract (arXiv)
Text-to-image diffusion models excel at translating language prompts into photorealistic images by implicitly grounding textual concepts through their cross-modal attention mechanisms. Recent multi-modal diffusion transformers extend this by introducing joint self-attention over concatenated image and text tokens, enabling richer and more scalable cross-modal alignment. However, a detailed understanding of how and where these attention maps contribute to image generation remains limited. In this paper, we introduce Seg4Diff (Segmentation for Diffusion), a systematic framework for analyzing the attention structures of MM-DiT, with a focus on how specific layers propagate semantic information from text to image. Through comprehensive analysis, we identify a semantic grounding expert layer, a specific MM-DiT block that consistently aligns text tokens with spatially coherent image regions, naturally producing high-quality semantic segmentation masks. We further demonstrate that applying a lightweight fine-tuning scheme with mask-annotated image data enhances the semantic grouping capabilities of these layers and thereby improves both segmentation performance and generated image fidelity. Our findings demonstrate that semantic grouping is an emergent property of diffusion transformers and can be selectively amplified to advance both segmentation and generation performance, paving the way for unified models that bridge visual perception and generation.
Key facts. Cited by 24 papers in the map (data through 14 Oct 2026). Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models. Builds on 63 of its 75 references that are in the map. First posted on arXiv 22 Sep 2025.
Builds on
63 of 75 references.
Closest ancestors · 6
Same direction, newest first
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- 2023Diffusion Models for Open-Vocabulary Segmentation15 Jun
- 2023Open-Vocabulary Panoptic Segmentation with Text-to-Image Diffusion Models8 Mar
Other references · 57
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50 most cited of 57 All 57 (JSON)
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Citing papers per year: 2025: 6; 2026: 18.
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- 2026MagicFuse: Single Image Fusion for Visual and Semantic Reinforcement2 Feb 2026
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