SimuScope: Realistic Endoscopic Synthetic Dataset Generation through Surgical Simulation and Diffusion Models
On the map: Diffusion models → Medical imaging and segmentation
Abstract (arXiv)
Computer-assisted surgical (CAS) systems enhance surgical execution and outcomes by providing advanced support to surgeons. These systems often rely on deep learning models trained on complex, challenging-to-annotate data. While synthetic data generation can address these challenges, enhancing the realism of such data is crucial. This work introduces a multi-stage pipeline for generating realistic synthetic data, featuring a fully-fledged surgical simulator that automatically produces all necessary annotations for modern CAS systems. This simulator generates a wide set of annotations that surpass those available in public synthetic datasets. Additionally, it offers a more complex and realistic simulation of surgical interactions, including the dynamics between surgical instruments and deformable anatomical environments, outperforming existing approaches. To further bridge the visual gap between synthetic and real data, we propose a lightweight and flexible image-to-image translation method based on Stable Diffusion (SD) and Low-Rank Adaptation (LoRA). This method leverages a limited amount of annotated data, enables efficient training, and maintains the integrity of annotations generated by our simulator. The proposed pipeline is experimentally validated and can translate synthetic images into images with real-world characteristics, which can generalize to real-world context, thereby improving both training and CAS guidance. The code and the dataset are available at https://github.com/SanoScience/SimuScope.
Key facts. Cited by 8 papers in the map (data through 14 Oct 2026). Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models. Builds on 50 of its 68 references that are in the map. First posted on arXiv 3 Dec 2024.
Builds on
50 of 68 references.
Closest ancestors · 13
Same direction, newest first
- 2024Fairness-Aware Data Augmentation for Cardiac MRI using Text-Conditioned Diffusion Models28 Mar
- 2024MedM2G: Unifying Medical Multi-Modal Generation via Cross-Guided Diffusion with Visual Invariant7 Mar
- 2023Adaptive Latent Diffusion Model for 3D Medical Image to Image Translation: Multi-modal Magnetic Resonance Imaging Study1 Nov
- 2023Ambiguous Medical Image Segmentation using Diffusion Models10 Apr
- 2023Zero-shot Medical Image Translation via Frequency-Guided Diffusion Models5 Apr
- 2023Memory-Efficient 3D Denoising Diffusion Models for Medical Image Processing27 Mar
- 2023CoLa-Diff: Conditional Latent Diffusion Model for Multi-Modal MRI Synthesis24 Mar
- 2023DiffMIC: Dual-Guidance Diffusion Network for Medical Image Classification19 Mar
- 2022DOLCE: A Model-Based Probabilistic Diffusion Framework for Limited-Angle CT Reconstruction22 Nov
- 2022MedSegDiff: Medical Image Segmentation with Diffusion Probabilistic Model1 Nov
- 2022Unsupervised Medical Image Translation with Adversarial Diffusion Models17 Jul
- 2022Diffusion Models for Medical Anomaly Detection8 Mar
Other references · 37
- 2017Attention Is All You Needcited by 60,361
- 2020Denoising Diffusion Probabilistic Modelscited by 21,076
- 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,380
- 2023Adding Conditional Control to Text-to-Image Diffusion Modelscited by 5,503
- 2022DreamBooth: Fine Tuning Text-to-Image Diffusion Models for Subject-Driven Generationcited by 3,300
- 2019Towards Robust Monocular Depth Estimation: Mixing Datasets for Zero-shot Cross-dataset Transfercited by 1,495
- 2023T2I-Adapter: Learning Adapters to Dig out More Controllable Ability for Text-to-Image Diffusion Modelscited by 1,351
- 2018Demystifying MMD GANscited by 1,293
- 2018Adafactor: Adaptive Learning Rates with Sublinear Memory Costcited by 905
- 2023GLIGEN: Open-Set Grounded Text-to-Image Generationcited by 781
- 2015Holistically-Nested Edge Detectioncited by 592
- 2023Training-Free Layout Control with Cross-Attention Guidancecited by 313
25 more
- 2023Rethinking FID: Towards a Better Evaluation Metric for Image Generationcited by 310
- 2023BoxDiff: Text-to-Image Synthesis with Training-Free Box-Constrained Diffusioncited by 282
- 2023Exposing flaws of generative model evaluation metrics and their unfair treatment of diffusion modelscited by 205
- 2022ReCo: Region-Controlled Text-to-Image Generationcited by 179
- 2024InstanceDiffusion: Instance-level Control for Image Generationcited by 175
- 2024ControlNet++: Improving Conditional Controls with Efficient Consistency Feedbackcited by 154
- 2021Rendezvous: Attention Mechanisms for the Recognition of Surgical Action Triplets in Endoscopic Videoscited by 141
- 2024MIGC: Multi-Instance Generation Controller for Text-to-Image Synthesiscited by 124
- 2023HumanSD: A Native Skeleton-Guided Diffusion Model for Human Image Generationcited by 105
- 2022HiFormer: Hierarchical Multi-scale Representations Using Transformers for Medical Image Segmentationcited by 95
- 2021Temporal Memory Relation Network for Workflow Recognition from Surgical Videocited by 66
- 2022Diffusion Deformable Model for 4D Temporal Medical Image Generationcited by 65
- 2023Controllable Text-to-Image Generation with GPT-4cited by 59
- 2022Diffusion Adversarial Representation Learning for Self-supervised Vessel Segmentationcited by 55
- 2019CAI4CAI: The Rise of Contextual Artificial Intelligence in Computer Assisted Interventionscited by 40
- 2019Generating large labeled data sets for laparoscopic image processing tasks using unpaired image-to-image translationcited by 38
- 2022Min-Max Similarity: A Contrastive Semi-Supervised Deep Learning Network for Surgical Tools Segmentationcited by 28
- 2021Long-Term Temporally Consistent Unpaired Video Translation from Simulated Surgical 3D Datacited by 21
- 2020Endo-Sim2Real: Consistency learning-based domain adaptation for instrument segmentationcited by 20
- 2021Mutually improved endoscopic image synthesis and landmark detection in unpaired image-to-image translationcited by 15
- 2020LC-GAN: Image-to-image Translation Based on Generative Adversarial Network for Endoscopic Imagescited by 11
- 2023Exploring Semantic Consistency in Unpaired Image Translation to Generate Data for Surgical Applicationscited by 9
- 2022Histogram of Oriented Gradients Meet Deep Learning: A Novel Multi-task Deep Network for Medical Image Semantic Segmentationcited by 4
- 2022Realistic Endoscopic Image Generation Method Using Virtual-to-real Image-domain Translationcited by 1
- 2022Virtual Reality Simulator for Fetoscopic Spina Bifida Repair Surgerycited by 1
Built on by
Citing papers per year: 2025: 5; 2026: 3.
8 papers.
- 2026From Articulated Kinematics to Routed Visual Control for Action-Conditioned Surgical Video Generationcited by 4
- 2025Mission Balance: Generating Under-represented Class Samples using Video Diffusion Modelscited by 1
- 2025Endoscopic Depth Estimation Based on Deep Learning: A Surveycited by 1
- 2025Mitigating Surgical Data Imbalance with Dual-Prediction Video Diffusion Modelcited by 1
- 2026SCARED-C: Corrected Camera Poses for Endoscopic Depth Estimationcited by 1
- 2025Clinically-guided Data Synthesis for Laryngeal Lesion Detectioncited by 0
- 2025Towards Application Aligned Synthetic Surgical Image Synthesiscited by 0
- 2026ASTRA-Net: Anatomy-Specific Transfer and Representation Alignment for Drug-Induced Sleep Endoscopy Segmentationcited by 0
- 2026ASTRA-Net: Anatomy-Specific Transfer and Representation Alignment for Drug-Induced Sleep Endoscopy Segmentation23 Jul 2026
- 2026SCARED-C: Corrected Camera Poses for Endoscopic Depth Estimation15 May 2026
- 2026From Articulated Kinematics to Routed Visual Control for Action-Conditioned Surgical Video Generation9 May 2026
- 2025Mitigating Surgical Data Imbalance with Dual-Prediction Video Diffusion Model7 Oct 2025
- 2025Towards Application Aligned Synthetic Surgical Image Synthesis23 Sep 2025
- 2025Clinically-guided Data Synthesis for Laryngeal Lesion Detection8 Aug 2025
- 2025Endoscopic Depth Estimation Based on Deep Learning: A Survey28 Jul 2025
- 2025Mission Balance: Generating Under-represented Class Samples using Video Diffusion Models14 May 2025
Similar, not cited
Close in wording, no citation either way
- 2023Navigating the Synthetic Realm: Harnessing Diffusion-based Models for Laparoscopic Text-to-Image Generation
- 2024Interactive Generation of Laparoscopic Videos with Diffusion Models
- 2024SurgicaL-CD: Generating Surgical Images via Unpaired Image Translation with Latent Consistency Diffusion Models
- 2025SG2VID: Scene Graphs Enable Fine-Grained Control for Video Synthesis
- 2021Simulation-to-Real domain adaptation with teacher-student learning for endoscopic instrument segmentation
- 2026Surgical Video Generation From Diffusion to World Models: A Survey
- 2026Hierarchical Curriculum Learning for Surgical Video Generation: Focusing on Bilateral Axillo-Breast Approach Robotic Thyroidectomy Datasets
- 2026EndoGSim: Physics-Aware 4D Dynamic Endoscopic Scene Simulations via MLLM-Guided Gaussian Splatting