mlsanityData to 14 Oct 2026

SimuScope: Realistic Endoscopic Synthetic Dataset Generation through Surgical Simulation and Diffusion Models

arXiv 2412.02332 ↗First posted 3 Dec 2024cs.CV eess.IVcited by 8

On the map: Diffusion models → Medical imaging and segmentation

Abstract (arXiv)

Computer-assisted surgical (CAS) systems enhance surgical execution and outcomes by providing advanced support to surgeons. These systems often rely on deep learning models trained on complex, challenging-to-annotate data. While synthetic data generation can address these challenges, enhancing the realism of such data is crucial. This work introduces a multi-stage pipeline for generating realistic synthetic data, featuring a fully-fledged surgical simulator that automatically produces all necessary annotations for modern CAS systems. This simulator generates a wide set of annotations that surpass those available in public synthetic datasets. Additionally, it offers a more complex and realistic simulation of surgical interactions, including the dynamics between surgical instruments and deformable anatomical environments, outperforming existing approaches. To further bridge the visual gap between synthetic and real data, we propose a lightweight and flexible image-to-image translation method based on Stable Diffusion (SD) and Low-Rank Adaptation (LoRA). This method leverages a limited amount of annotated data, enables efficient training, and maintains the integrity of annotations generated by our simulator. The proposed pipeline is experimentally validated and can translate synthetic images into images with real-world characteristics, which can generalize to real-world context, thereby improving both training and CAS guidance. The code and the dataset are available at https://github.com/SanoScience/SimuScope.

Key facts. Cited by 8 papers in the map (data through 14 Oct 2026). Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models. Builds on 50 of its 68 references that are in the map. First posted on arXiv 3 Dec 2024.

Builds on

50 of 68 references.

Closest ancestors · 13

Same direction, newest first

  1. 2024Fairness-Aware Data Augmentation for Cardiac MRI using Text-Conditioned Diffusion Models28 Mar
  2. 2024MedM2G: Unifying Medical Multi-Modal Generation via Cross-Guided Diffusion with Visual Invariant7 Mar
  3. 2023Adaptive Latent Diffusion Model for 3D Medical Image to Image Translation: Multi-modal Magnetic Resonance Imaging Study1 Nov
  4. 2023Ambiguous Medical Image Segmentation using Diffusion Models10 Apr
  5. 2023Zero-shot Medical Image Translation via Frequency-Guided Diffusion Models5 Apr
  6. 2023Memory-Efficient 3D Denoising Diffusion Models for Medical Image Processing27 Mar
  7. 2023CoLa-Diff: Conditional Latent Diffusion Model for Multi-Modal MRI Synthesis24 Mar
  8. 2023DiffMIC: Dual-Guidance Diffusion Network for Medical Image Classification19 Mar
  9. 2022DOLCE: A Model-Based Probabilistic Diffusion Framework for Limited-Angle CT Reconstruction22 Nov
  10. 2022MedSegDiff: Medical Image Segmentation with Diffusion Probabilistic Model1 Nov
  11. 2022Unsupervised Medical Image Translation with Adversarial Diffusion Models17 Jul
  12. 2022Diffusion Models for Medical Anomaly Detection8 Mar
1 more
  1. 2021DiffuseMorph: Unsupervised Deformable Image Registration Using Diffusion Model9 Dec

Other references · 37

  1. 2017Attention Is All You Needcited by 60,361
  2. 2020Denoising Diffusion Probabilistic Modelscited by 21,076
  3. 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,380
  4. 2023Adding Conditional Control to Text-to-Image Diffusion Modelscited by 5,503
  5. 2022DreamBooth: Fine Tuning Text-to-Image Diffusion Models for Subject-Driven Generationcited by 3,300
  6. 2019Towards Robust Monocular Depth Estimation: Mixing Datasets for Zero-shot Cross-dataset Transfercited by 1,495
  7. 2023T2I-Adapter: Learning Adapters to Dig out More Controllable Ability for Text-to-Image Diffusion Modelscited by 1,351
  8. 2018Demystifying MMD GANscited by 1,293
  9. 2018Adafactor: Adaptive Learning Rates with Sublinear Memory Costcited by 905
  10. 2023GLIGEN: Open-Set Grounded Text-to-Image Generationcited by 781
  11. 2015Holistically-Nested Edge Detectioncited by 592
  12. 2023Training-Free Layout Control with Cross-Attention Guidancecited by 313
25 more
  1. 2023Rethinking FID: Towards a Better Evaluation Metric for Image Generationcited by 310
  2. 2023BoxDiff: Text-to-Image Synthesis with Training-Free Box-Constrained Diffusioncited by 282
  3. 2023Exposing flaws of generative model evaluation metrics and their unfair treatment of diffusion modelscited by 205
  4. 2022ReCo: Region-Controlled Text-to-Image Generationcited by 179
  5. 2024InstanceDiffusion: Instance-level Control for Image Generationcited by 175
  6. 2024ControlNet++: Improving Conditional Controls with Efficient Consistency Feedbackcited by 154
  7. 2021Rendezvous: Attention Mechanisms for the Recognition of Surgical Action Triplets in Endoscopic Videoscited by 141
  8. 2024MIGC: Multi-Instance Generation Controller for Text-to-Image Synthesiscited by 124
  9. 2023HumanSD: A Native Skeleton-Guided Diffusion Model for Human Image Generationcited by 105
  10. 2022HiFormer: Hierarchical Multi-scale Representations Using Transformers for Medical Image Segmentationcited by 95
  11. 2021Temporal Memory Relation Network for Workflow Recognition from Surgical Videocited by 66
  12. 2022Diffusion Deformable Model for 4D Temporal Medical Image Generationcited by 65
  13. 2023Controllable Text-to-Image Generation with GPT-4cited by 59
  14. 2022Diffusion Adversarial Representation Learning for Self-supervised Vessel Segmentationcited by 55
  15. 2019CAI4CAI: The Rise of Contextual Artificial Intelligence in Computer Assisted Interventionscited by 40
  16. 2019Generating large labeled data sets for laparoscopic image processing tasks using unpaired image-to-image translationcited by 38
  17. 2022Min-Max Similarity: A Contrastive Semi-Supervised Deep Learning Network for Surgical Tools Segmentationcited by 28
  18. 2021Long-Term Temporally Consistent Unpaired Video Translation from Simulated Surgical 3D Datacited by 21
  19. 2020Endo-Sim2Real: Consistency learning-based domain adaptation for instrument segmentationcited by 20
  20. 2021Mutually improved endoscopic image synthesis and landmark detection in unpaired image-to-image translationcited by 15
  21. 2020LC-GAN: Image-to-image Translation Based on Generative Adversarial Network for Endoscopic Imagescited by 11
  22. 2023Exploring Semantic Consistency in Unpaired Image Translation to Generate Data for Surgical Applicationscited by 9
  23. 2022Histogram of Oriented Gradients Meet Deep Learning: A Novel Multi-task Deep Network for Medical Image Semantic Segmentationcited by 4
  24. 2022Realistic Endoscopic Image Generation Method Using Virtual-to-real Image-domain Translationcited by 1
  25. 2022Virtual Reality Simulator for Fetoscopic Spina Bifida Repair Surgerycited by 1

Built on by

Cited by year (2026 to 14 Oct)

Citing papers per year: 2025: 5; 2026: 3.

8 papers.

Similar, not cited

Close in wording, no citation either way

  1. 2023Navigating the Synthetic Realm: Harnessing Diffusion-based Models for Laparoscopic Text-to-Image Generation
  2. 2024Interactive Generation of Laparoscopic Videos with Diffusion Models
  3. 2024SurgicaL-CD: Generating Surgical Images via Unpaired Image Translation with Latent Consistency Diffusion Models
  4. 2025SG2VID: Scene Graphs Enable Fine-Grained Control for Video Synthesis
  5. 2021Simulation-to-Real domain adaptation with teacher-student learning for endoscopic instrument segmentation
  6. 2026Surgical Video Generation From Diffusion to World Models: A Survey
  7. 2026Hierarchical Curriculum Learning for Surgical Video Generation: Focusing on Bilateral Axillo-Breast Approach Robotic Thyroidectomy Datasets
  8. 2026EndoGSim: Physics-Aware 4D Dynamic Endoscopic Scene Simulations via MLLM-Guided Gaussian Splatting