Mitigating attribute amplification in counterfactual image generation
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Abstract (arXiv)
Causal generative modelling is gaining interest in medical imaging due to its ability to answer interventional and counterfactual queries. Most work focuses on generating counterfactual images that look plausible, using auxiliary classifiers to enforce effectiveness of simulated interventions. We investigate pitfalls in this approach, discovering the issue of attribute amplification, where unrelated attributes are spuriously affected during interventions, leading to biases across protected characteristics and disease status. We show that attribute amplification is caused by the use of hard labels in the counterfactual training process and propose soft counterfactual fine-tuning to mitigate this issue. Our method substantially reduces the amplification effect while maintaining effectiveness of generated images, demonstrated on a large chest X-ray dataset. Our work makes an important advancement towards more faithful and unbiased causal modelling in medical imaging.
Key facts. Cited by 12 papers in the map (data through 7 Oct 2026). Builds on 21 of its 29 references that are in the map. First posted on arXiv 14 Mar 2024.
Builds on
21 of 29 references.
References · 21
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9 more
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Built on by
Citing papers per year: 2024: 1; 2025: 5; 2026: 6.
12 papers.
- 2024Robust image representations with counterfactual contrastive learningcited by 12
- 2025Diffusion Counterfactual Generation with Semantic Abductioncited by 8
- 2025Towards Desiderata-Driven Design of Visual Counterfactual Explainerscited by 7
- 2025Counterfactual Identifiability via Dynamic Optimal Transportcited by 5
- 2025Segmentor-Guided Counterfactual Fine-Tuning for Locally Coherent and Targeted Image Synthesiscited by 2
- 2026Scaling Generative Foundation Models for Chest Radiography with Rectified Flow Transformerscited by 2
- 2026An Interpretable Local Editing Model for Counterfactual Medical Image Generationcited by 1
- 2026When the Edit Changes the Patient: Measuring Identity Preservation in Counterfactual Retinal Imagescited by 1
- 2025Diffusion-based Counterfactual Augmentation: Towards Robust and Interpretable Knee Osteoarthritis Gradingcited by 0
- 2026Positional Segmentor-Guided Counterfactual Fine-Tuning for Spatially Localized Image Synthesiscited by 0
- 2026Generating Medical Image Counterfactuals using Causal Explanationscited by 0
- 2026A Data-Interventional Framework for Auditing Privacy and Fairness in Generative Medical Imagingcited by 0
- 2026A Data-Interventional Framework for Auditing Privacy and Fairness in Generative Medical Imaging22 Sep 2026
- 2026Generating Medical Image Counterfactuals using Causal Explanations2 Sep 2026
- 2026When the Edit Changes the Patient: Measuring Identity Preservation in Counterfactual Retinal Images24 Aug 2026
- 2026Scaling Generative Foundation Models for Chest Radiography with Rectified Flow Transformers17 Jun 2026
- 2026Positional Segmentor-Guided Counterfactual Fine-Tuning for Spatially Localized Image Synthesis22 Mar 2026
- 2026An Interpretable Local Editing Model for Counterfactual Medical Image Generation28 Feb 2026
- 2025Counterfactual Identifiability via Dynamic Optimal Transport9 Oct 2025
- 2025Segmentor-Guided Counterfactual Fine-Tuning for Locally Coherent and Targeted Image Synthesis29 Sep 2025
- 2025Diffusion-based Counterfactual Augmentation: Towards Robust and Interpretable Knee Osteoarthritis Grading18 Jun 2025
- 2025Towards Desiderata-Driven Design of Visual Counterfactual Explainers17 Jun 2025
- 2025Diffusion Counterfactual Generation with Semantic Abduction9 Jun 2025
- 2024Robust image representations with counterfactual contrastive learning16 Sep 2024