From RAG to QA-RAG: Integrating Generative AI for Pharmaceutical Regulatory Compliance Process
On the map: Retrieval-augmented generation → RAG pipeline design and evaluation
Abstract (arXiv)
Regulatory compliance in the pharmaceutical industry entails navigating through complex and voluminous guidelines, often requiring significant human resources. To address these challenges, our study introduces a chatbot model that utilizes generative AI and the Retrieval Augmented Generation (RAG) method. This chatbot is designed to search for guideline documents relevant to the user inquiries and provide answers based on the retrieved guidelines. Recognizing the inherent need for high reliability in this domain, we propose the Question and Answer Retrieval Augmented Generation (QA-RAG) model. In comparative experiments, the QA-RAG model demonstrated a significant improvement in accuracy, outperforming all other baselines including conventional RAG methods. This paper details QA-RAG's structure and performance evaluation, emphasizing its potential for the regulatory compliance domain in the pharmaceutical industry and beyond. We have made our work publicly available for further research and development.
Key facts. No citing papers in the map yet (data through 7 Oct 2026). Placed in RAG pipeline design and evaluation, one of 15 directions in Retrieval-augmented generation. Builds on 30 of its 47 references that are in the map. First posted on arXiv 26 Jan 2024.
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17 more
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