MAPSeg: Unified Unsupervised Domain Adaptation for Heterogeneous Medical Image Segmentation Based on 3D Masked Autoencoding and Pseudo-Labeling
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Abstract (arXiv)
Robust segmentation is critical for deriving quantitative measures from large-scale, multi-center, and longitudinal medical scans. Manually annotating medical scans, however, is expensive and labor-intensive and may not always be available in every domain. Unsupervised domain adaptation (UDA) is a well-studied technique that alleviates this label-scarcity problem by leveraging available labels from another domain. In this study, we introduce Masked Autoencoding and Pseudo-Labeling Segmentation (MAPSeg), a unified UDA framework with great versatility and superior performance for heterogeneous and volumetric medical image segmentation. To the best of our knowledge, this is the first study that systematically reviews and develops a framework to tackle four different domain shifts in medical image segmentation. More importantly, MAPSeg is the first framework that can be applied to centralized, federated, and test-time UDA while maintaining comparable performance. We compare MAPSeg with previous state-of-the-art methods on a private infant brain MRI dataset and a public cardiac CT-MRI dataset, and MAPSeg outperforms others by a large margin (10.5 Dice improvement on the private MRI dataset and 5.7 on the public CT-MRI dataset). MAPSeg poses great practical value and can be applied to real-world problems. GitHub: https://github.com/XuzheZ/MAPSeg/.
Key facts. Cited by 25 papers in the map (data through 14 Oct 2026). Builds on 53 of its 92 references that are in the map. First posted on arXiv 16 Mar 2023.
Builds on
53 of 92 references.
References · 53
- 2015Deep Residual Learning for Image Recognitioncited by 52,096
- 2016Communication-Efficient Learning of Deep Networks from Decentralized Datacited by 7,669
- 2021Masked Autoencoders Are Scalable Vision Learnerscited by 7,403
- 2017mixup: Beyond Empirical Risk Minimizationcited by 5,183
- 2016SGDR: Stochastic Gradient Descent with Warm Restartscited by 5,045
- 2020Bootstrap your own latent: A new approach to self-supervised Learningcited by 4,750
- 2019Advances and Open Problems in Federated Learningcited by 3,046
- 2017Rethinking Atrous Convolution for Semantic Image Segmentationcited by 2,161
- 2016Context Encoders: Feature Learning by Inpaintingcited by 1,428
- 2018Moment Matching for Multi-Source Domain Adaptationcited by 1,331
- 2015Learning Transferable Features with Deep Adaptation Networkscited by 1,329
- 2021SimMIM: A Simple Framework for Masked Image Modelingcited by 1,153
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- 2017CyCADA: Cycle-Consistent Adversarial Domain Adaptationcited by 1,082
- 2015Unsupervised Visual Representation Learning by Context Predictioncited by 1,066
- 2016Temporal Ensembling for Semi-Supervised Learningcited by 1,057
- 2019Data-Efficient Image Recognition with Contrastive Predictive Codingcited by 673
- 2018ADVENT: Adversarial Entropy Minimization for Domain Adaptation in Semantic Segmentationcited by 623
- 2016Regularization With Stochastic Transformations and Perturbations for Deep Semi-Supervised Learningcited by 441
- 2021Self-Supervised Pre-Training of Swin Transformers for 3D Medical Image Analysiscited by 422
- 2019Confidence Regularized Self-Trainingcited by 419
- 2016Unsupervised Domain Adaptation with Residual Transfer Networkscited by 341
- 2021DAFormer: Improving Network Architectures and Training Strategies for Domain-Adaptive Semantic Segmentationcited by 300
- 2021Prototypical Pseudo Label Denoising and Target Structure Learning for Domain Adaptive Semantic Segmentationcited by 268
- 2020Rectifying Pseudo Label Learning via Uncertainty Estimation for Domain Adaptive Semantic Segmentationcited by 222
- 2022Test-Time Training with Masked Autoencoderscited by 212
- 2022MIC: Masked Image Consistency for Context-Enhanced Domain Adaptationcited by 178
- 2020TorchIO: A Python library for efficient loading, preprocessing, augmentation and patch-based sampling of medical images in deep learningcited by 177
- 2021Source-Free Domain Adaptation for Semantic Segmentationcited by 168
- 2022HRDA: Context-Aware High-Resolution Domain-Adaptive Semantic Segmentationcited by 164
- 2018Multi-Institutional Deep Learning Modeling Without Sharing Patient Data: A Feasibility Study on Brain Tumor Segmentationcited by 149
- 2020Unsupervised Bidirectional Cross-Modality Adaptation via Deeply Synergistic Image and Feature Alignment for Medical Image Segmentationcited by 134
- 2016Multivariate mixture model for myocardium segmentation combining multi-source imagescited by 133
- 2022SynthStrip: Skull-Stripping for Any Brain Imagecited by 127
- 2019Synergistic Image and Feature Adaptation: Towards Cross-Modality Domain Adaptation for Medical Image Segmentationcited by 121
- 2022What to Hide from Your Students: Attention-Guided Masked Image Modelingcited by 118
- 2022Revealing the Dark Secrets of Masked Image Modelingcited by 117
- 2017No More Discrimination: Cross City Adaptation of Road Scene Segmenterscited by 111
- 2020Test-Time Adaptable Neural Networks for Robust Medical Image Segmentationcited by 102
- 2020Contextual-Relation Consistent Domain Adaptation for Semantic Segmentationcited by 70
- 2021SimPLE: Similar Pseudo Label Exploitation for Semi-Supervised Classificationcited by 68
- 2021Source-Free Domain Adaptive Fundus Image Segmentation with Denoised Pseudo-Labelingcited by 61
- 2019Collaborative Global-Local Networks for Memory-Efficient Segmentation of Ultra-High Resolution Imagescited by 51
- 2022Understanding Masked Image Modeling via Learning Occlusion Invariant Featurecited by 50
- 2022On Data Scaling in Masked Image Modelingcited by 46
- 2021Federated Multi-Target Domain Adaptationcited by 44
- 2021FedCor: Correlation-Based Active Client Selection Strategy for Heterogeneous Federated Learningcited by 43
- 2020Multi-Site Infant Brain Segmentation Algorithms: The iSeg-2019 Challengecited by 28
- 2020Federated Semi-Supervised Learning for COVID Region Segmentation in Chest CT using Multi-National Data from China, Italy, Japancited by 23
- 2022FedMix: Mixed Supervised Federated Learning for Medical Image Segmentationcited by 23
- 2021Margin Preserving Self-paced Contrastive Learning Towards Domain Adaptation for Medical Image Segmentationcited by 20
50 most cited of 53 All 53 (JSON)
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Citing papers per year: 2024: 5; 2025: 9; 2026: 11.
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- 2024Revisiting MAE pre-training for 3D medical image segmentationcited by 35
- 2024Masked Image Modeling: A Surveycited by 29
- 2024Unleashing the Potential of Vision-Language Pre-Training for 3D Zero-Shot Lesion Segmentation via Mask-Attribute Alignmentcited by 7
- 2025BEN: Using Confidence-Guided Matting for Dichotomous Image Segmentationcited by 7
- 2024Diffuse-UDA: Addressing Unsupervised Domain Adaptation in Medical Image Segmentation with Appearance and Structure Aligned Diffusion Modelscited by 6
- 2024Aggregated Attributions for Explanatory Analysis of 3D Segmentation Modelscited by 5
- 2025Atlas is Your Perfect Context: One-Shot Customization for Generalizable Foundational Medical Image Segmentationcited by 3
- 2025Neuroverse3D: Developing In-Context Learning Universal Model for Neuroimaging in 3Dcited by 1
- 2025ModalFormer: Multimodal Transformer for Low-Light Image Enhancementcited by 1
- 2025Unified and Semantically Grounded Domain Adaptation for Medical Image Segmentationcited by 1
- 2025COME: Dual Structure-Semantic Learning with Collaborative MoE for Universal Lesion Detection Across Heterogeneous Ultrasound Datasetscited by 1
- 2025TK-Mamba: Marrying KAN With Mamba for Text-Driven 3D Medical Image Segmentationcited by 0
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- 2026Addressing data annotation scarcity in Brain Tumor Segmentation on 3D MRI scan Using a Semi-Supervised Teacher-Student Frameworkcited by 0
- 2026Unsupervised Domain Adaptation with Target-Only Margin Disparity Discrepancycited by 0
- 2026SHAPE: Structure-aware Hierarchical Unsupervised Domain Adaptation with Plausibility Evaluation for Medical Image Segmentationcited by 0
- 2026Why Invariance is Not Enough for Biomedical Domain Generalization and How to Fix Itcited by 0
- 2026PolarMAE: Efficient Fetal Ultrasound Pre-training via Semantic Screening and Polar-Guided Maskingcited by 0
- 2026A Two-Stage Multi-Modal MRI Framework for Lifespan Brain Age Predictioncited by 0
- 2026From Adaptation to Generalization: Adaptive Visual Prompting for Medical Image Segmentationcited by 0
- 2026ASTRA-Net: Anatomy-Specific Transfer and Representation Alignment for Drug-Induced Sleep Endoscopy Segmentationcited by 0
- 2026UnDA: Unpaired Domain Alignment for Cross-Modal Knowledge Transfer in Medical Imagingcited by 0
- 2026Test-time Adaptation of Pelvic Bone Segmentation Models via Dynamic Reliability-Guidedcited by 0
- 2026Unsupervised Adaptation of 3D CT Foundation Models for 3D CBCT Segmentationcited by 0
- 2026Unsupervised Adaptation of 3D CT Foundation Models for 3D CBCT Segmentation27 Aug 2026
- 2026Test-time Adaptation of Pelvic Bone Segmentation Models via Dynamic Reliability-Guided1 Aug 2026
- 2026UnDA: Unpaired Domain Alignment for Cross-Modal Knowledge Transfer in Medical Imaging23 Jul 2026
- 2026ASTRA-Net: Anatomy-Specific Transfer and Representation Alignment for Drug-Induced Sleep Endoscopy Segmentation23 Jul 2026
- 2026From Adaptation to Generalization: Adaptive Visual Prompting for Medical Image Segmentation19 Apr 2026
- 2026A Two-Stage Multi-Modal MRI Framework for Lifespan Brain Age Prediction17 Apr 2026
- 2026PolarMAE: Efficient Fetal Ultrasound Pre-training via Semantic Screening and Polar-Guided Masking17 Apr 2026
- 2026Why Invariance is Not Enough for Biomedical Domain Generalization and How to Fix It2 Apr 2026
- 2026SHAPE: Structure-aware Hierarchical Unsupervised Domain Adaptation with Plausibility Evaluation for Medical Image Segmentation23 Mar 2026
- 2026Unsupervised Domain Adaptation with Target-Only Margin Disparity Discrepancy10 Mar 2026
- 2026Addressing data annotation scarcity in Brain Tumor Segmentation on 3D MRI scan Using a Semi-Supervised Teacher-Student Framework9 Feb 2026
- 2025Atlas is Your Perfect Context: One-Shot Customization for Generalizable Foundational Medical Image Segmentation20 Dec 2025
13 more
- 2025Reducing Domain Gap with Diffusion-Based Domain Adaptation for Cell Counting12 Dec 2025
- 2025COME: Dual Structure-Semantic Learning with Collaborative MoE for Universal Lesion Detection Across Heterogeneous Ultrasound Datasets13 Aug 2025
- 2025Unified and Semantically Grounded Domain Adaptation for Medical Image Segmentation12 Aug 2025
- 2025ModalFormer: Multimodal Transformer for Low-Light Image Enhancement27 Jul 2025
- 2025Contrast-Invariant Self-supervised Segmentation for Quantitative Placental MRI30 May 2025
- 2025TK-Mamba: Marrying KAN With Mamba for Text-Driven 3D Medical Image Segmentation24 May 2025
- 2025Neuroverse3D: Developing In-Context Learning Universal Model for Neuroimaging in 3D4 Mar 2025
- 2025BEN: Using Confidence-Guided Matting for Dichotomous Image Segmentation8 Jan 2025
- 2024Revisiting MAE pre-training for 3D medical image segmentation30 Oct 2024
- 2024Unleashing the Potential of Vision-Language Pre-Training for 3D Zero-Shot Lesion Segmentation via Mask-Attribute Alignment21 Oct 2024
- 2024Masked Image Modeling: A Survey13 Aug 2024
- 2024Diffuse-UDA: Addressing Unsupervised Domain Adaptation in Medical Image Segmentation with Appearance and Structure Aligned Diffusion Models12 Aug 2024
- 2024Aggregated Attributions for Explanatory Analysis of 3D Segmentation Models23 Jul 2024
- 2024Revisiting MAE pre-training for 3D medical image segmentationcited by 35
- 2024Masked Image Modeling: A Surveycited by 29
- 2025BEN: Using Confidence-Guided Matting for Dichotomous Image Segmentationcited by 7
- 2024Aggregated Attributions for Explanatory Analysis of 3D Segmentation Modelscited by 5
- 2025Atlas is Your Perfect Context: One-Shot Customization for Generalizable Foundational Medical Image Segmentationcited by 3
- 2025Neuroverse3D: Developing In-Context Learning Universal Model for Neuroimaging in 3Dcited by 1
- 2025ModalFormer: Multimodal Transformer for Low-Light Image Enhancementcited by 1
- 2025Unified and Semantically Grounded Domain Adaptation for Medical Image Segmentationcited by 1
- 2025Contrast-Invariant Self-supervised Segmentation for Quantitative Placental MRIcited by 0
- 2025Reducing Domain Gap with Diffusion-Based Domain Adaptation for Cell Countingcited by 0
- 2026Unsupervised Domain Adaptation with Target-Only Margin Disparity Discrepancycited by 0
- 2026SHAPE: Structure-aware Hierarchical Unsupervised Domain Adaptation with Plausibility Evaluation for Medical Image Segmentationcited by 0
12 most cited of 20 All 20 (JSON)
- 2026Unsupervised Adaptation of 3D CT Foundation Models for 3D CBCT Segmentation27 Aug 2026
- 2026Test-time Adaptation of Pelvic Bone Segmentation Models via Dynamic Reliability-Guided1 Aug 2026
- 2026UnDA: Unpaired Domain Alignment for Cross-Modal Knowledge Transfer in Medical Imaging23 Jul 2026
- 2026ASTRA-Net: Anatomy-Specific Transfer and Representation Alignment for Drug-Induced Sleep Endoscopy Segmentation23 Jul 2026
- 2026From Adaptation to Generalization: Adaptive Visual Prompting for Medical Image Segmentation19 Apr 2026
- 2026A Two-Stage Multi-Modal MRI Framework for Lifespan Brain Age Prediction17 Apr 2026
- 2026PolarMAE: Efficient Fetal Ultrasound Pre-training via Semantic Screening and Polar-Guided Masking17 Apr 2026
- 2026Why Invariance is Not Enough for Biomedical Domain Generalization and How to Fix It2 Apr 2026
- 2026SHAPE: Structure-aware Hierarchical Unsupervised Domain Adaptation with Plausibility Evaluation for Medical Image Segmentation23 Mar 2026
- 2026Unsupervised Domain Adaptation with Target-Only Margin Disparity Discrepancy10 Mar 2026
- 2025Atlas is Your Perfect Context: One-Shot Customization for Generalizable Foundational Medical Image Segmentation20 Dec 2025
- 2025Reducing Domain Gap with Diffusion-Based Domain Adaptation for Cell Counting12 Dec 2025
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