Bayesian MRI Reconstruction with Joint Uncertainty Estimation using Diffusion Models
On the map: Diffusion models → Medical imaging and segmentation
Abstract (arXiv)
We introduce a framework that enables efficient sampling from learned probability distributions for MRI reconstruction. Different from conventional deep learning-based MRI reconstruction techniques, samples are drawn from the posterior distribution given the measured k-space using the Markov chain Monte Carlo (MCMC) method. In addition to the maximum a posteriori (MAP) estimate for the image, which can be obtained with conventional methods, the minimum mean square error (MMSE) estimate and uncertainty maps can also be computed. The data-driven Markov chains are constructed from the generative model learned from a given image database and are independent of the forward operator that is used to model the k-space measurement. This provides flexibility because the method can be applied to k-space acquired with different sampling schemes or receive coils using the same pre-trained models. Furthermore, we use a framework based on a reverse diffusion process to be able to utilize advanced generative models. The performance of the method is evaluated on an open dataset using 10-fold undersampling in k-space.
Key facts. Cited by 46 papers in the map (data through 7 Oct 2026). Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models. Builds on 17 of its 49 references that are in the map. First posted on arXiv 3 Feb 2022.
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17 of 49 references.
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Other references · 16
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Citing papers per year: 2022: 2; 2023: 14; 2024: 12; 2025: 10; 2026: 8.
46 papers.
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- 2023Decomposed Diffusion Sampler for Accelerating Large-Scale Inverse Problemscited by 129
- 2025InverseBench: Benchmarking Plug-and-Play Diffusion Priors for Inverse Problems in Physical Sciencescited by 67
- 2023Solving Inverse Problems with Score-Based Generative Priors learned from Noisy Datacited by 40
- 2023A review of uncertainty quantification in medical image analysis: probabilistic and non-probabilistic methodscited by 39
- 2024On the Challenges and Opportunities in Generative AIcited by 31
- 2022Stable Deep MRI Reconstruction using Generative Priorscited by 21
- 2023The Emergence of Reproducibility and Generalizability in Diffusion Modelscited by 21
- 2023Diffusion Modeling with Domain-conditioned Prior Guidance for Accelerated MRI and qMRI Reconstructioncited by 20
- 2023MRI Reconstruction with Side Information using Diffusion Modelscited by 15
- 2023Correlated and Multi-frequency Diffusion Modeling for Highly Under-sampled MRI Reconstructioncited by 14
- 2023Learning Fourier-Constrained Diffusion Bridges for MRI Reconstructioncited by 13
- 2022One-shot Generative Prior in Hankel-k-space for Parallel Imaging Reconstructioncited by 11
34 more
- 2023A Survey of Emerging Applications of Diffusion Probabilistic Models in MRIcited by 9
- 2024Self-Supervised Adversarial Diffusion Models for Fast MRI Reconstructioncited by 9
- 2024Noise Level Adaptive Diffusion Model for Robust Reconstruction of Accelerated MRIcited by 6
- 2025Diffusion at Absolute Zero: Langevin Sampling Using Successive Moreau Envelopes [conference paper]cited by 6
- 2024Highly Accelerated MRI via Implicit Neural Representation Guided Posterior Sampling of Diffusion Modelscited by 5
- 2023Investigating the Adversarial Robustness of Density Estimation Using the Probability Flow ODEcited by 4
- 2024Autoregressive Image Diffusion: Generation of Image Sequence and Application in MRIcited by 4
- 2024Robust multi-coil MRI reconstruction via self-supervised denoisingcited by 4
- 2025Antithetic Noise in Diffusion Modelscited by 4
- 2025Self-diffusion for Solving Inverse Problemscited by 4
- 2023PixCUE: Joint Uncertainty Estimation and Image Reconstruction in MRI using Deep Pixel Classificationcited by 3
- 2023Generative Priors for MRI Reconstruction Trained from Magnitude-Only Images Using Phase Augmentationcited by 3
- 2024INFusion: Diffusion Regularized Implicit Neural Representations for 2D and 3D accelerated MRI reconstructioncited by 3
- 2024Denoising Diffusion Probabilistic Models for Magnetic Resonance Fingerprintingcited by 3
- 2023Joint Non-Linear MRI Inversion with Diffusion Priorscited by 2
- 2024Robust Simultaneous Multislice MRI Reconstruction Using Slice-Wise Learned Generative Diffusion Priorscited by 2
- 2024Sub-DM:Subspace Diffusion Model with Orthogonal Decomposition for MRI Reconstructioncited by 2
- 2024Fast MRI for All: Bridging Access Gaps by Training without Raw Datacited by 2
- 2025Unsupervised Radar Point Cloud Enhancement via Arbitrary LiDAR Guided Diffusion Priorcited by 2
- 2025How many measurements are enough? Bayesian recovery in inverse problems with general distributionscited by 2
- 2025Guiding Quantitative MRI Reconstruction with Phase-wise Uncertaintycited by 1
- 2025A Comprehensive Survey on Magnetic Resonance Image Reconstructioncited by 1
- 2025Diffusion Probabilistic Generative Models for Accelerated, in-NICU Permanent Magnet Neonatal MRIcited by 1
- 2026MUST: Modality-Specific Representation-Aware Transformer for Diffusion-Enhanced Survival Prediction with Missing Modalitycited by 1
- 2023Bias-Reduced Neural Networks for Parameter Estimation in Quantitative MRIcited by 0
- 2024Real-time cardiac cine MRI -- A comparison of a diffusion probabilistic model with alternative state-of-the-art image reconstruction techniques for undersampled spiral acquisitionscited by 0
- 2025Fast and Robust Diffusion Posterior Sampling for MR Image Reconstruction Using the Preconditioned Unadjusted Langevin Algorithmcited by 0
- 2026Beyond Accuracy: Evaluating Posterior Fidelity of Diffusion Inverse Solverscited by 0
- 2026MRI2Qmap: multi-parametric quantitative mapping with MRI-driven denoising priorscited by 0
- 2026Accelerating Stroke MRI with Diffusion Probabilistic Models through Large-Scale Pre-training and Target-Specific Fine-Tuningcited by 0
- 2026CARE: Training-Free Controllable Restoration for Medical Images via Dual-Latent Steeringcited by 0
- 2026Product-of-Gaussian-Mixture Diffusion Models for Joint Nonlinear MRI Reconstructioncited by 0
- 2026Consistency Models for Fast MRI Reconstruction Using Regularization by Denoisingcited by 0
- 2026Uncertainty-Aware 3D Residual Wavelet Diffusion for Ultra Low-Field MRI Super-Resolutioncited by 0
- 2026Uncertainty-Aware 3D Residual Wavelet Diffusion for Ultra Low-Field MRI Super-Resolution21 Sep 2026
- 2026Consistency Models for Fast MRI Reconstruction Using Regularization by Denoising20 Aug 2026
- 2026Product-of-Gaussian-Mixture Diffusion Models for Joint Nonlinear MRI Reconstruction11 May 2026
- 2026MUST: Modality-Specific Representation-Aware Transformer for Diffusion-Enhanced Survival Prediction with Missing Modality27 Mar 2026
- 2026CARE: Training-Free Controllable Restoration for Medical Images via Dual-Latent Steering26 Mar 2026
- 2026Accelerating Stroke MRI with Diffusion Probabilistic Models through Large-Scale Pre-training and Target-Specific Fine-Tuning13 Mar 2026
- 2026MRI2Qmap: multi-parametric quantitative mapping with MRI-driven denoising priors11 Mar 2026
- 2026Beyond Accuracy: Evaluating Posterior Fidelity of Diffusion Inverse Solvers4 Feb 2026
- 2025Fast and Robust Diffusion Posterior Sampling for MR Image Reconstruction Using the Preconditioned Unadjusted Langevin Algorithm5 Dec 2025
- 2025Self-diffusion for Solving Inverse Problems24 Oct 2025
- 2025Antithetic Noise in Diffusion Models6 Jun 2025
- 2025Diffusion Probabilistic Generative Models for Accelerated, in-NICU Permanent Magnet Neonatal MRI21 May 2025
34 more
- 2025How many measurements are enough? Bayesian recovery in inverse problems with general distributions15 May 2025
- 2025Unsupervised Radar Point Cloud Enhancement via Arbitrary LiDAR Guided Diffusion Prior15 May 2025
- 2025InverseBench: Benchmarking Plug-and-Play Diffusion Priors for Inverse Problems in Physical Sciences14 Mar 2025
- 2025A Comprehensive Survey on Magnetic Resonance Image Reconstruction10 Mar 2025
- 2025Guiding Quantitative MRI Reconstruction with Phase-wise Uncertainty28 Feb 2025
- 2025Diffusion at Absolute Zero: Langevin Sampling Using Successive Moreau Envelopes [conference paper]3 Feb 2025
- 2024Fast MRI for All: Bridging Access Gaps by Training without Raw Data20 Nov 2024
- 2024Robust multi-coil MRI reconstruction via self-supervised denoising19 Nov 2024
- 2024Sub-DM:Subspace Diffusion Model with Orthogonal Decomposition for MRI Reconstruction6 Nov 2024
- 2024Denoising Diffusion Probabilistic Models for Magnetic Resonance Fingerprinting29 Oct 2024
- 2024Real-time cardiac cine MRI -- A comparison of a diffusion probabilistic model with alternative state-of-the-art image reconstruction techniques for undersampled spiral acquisitions7 Oct 2024
- 2024Robust Simultaneous Multislice MRI Reconstruction Using Slice-Wise Learned Generative Diffusion Priors31 Jul 2024
- 2024Highly Accelerated MRI via Implicit Neural Representation Guided Posterior Sampling of Diffusion Models3 Jul 2024
- 2024Self-Supervised Adversarial Diffusion Models for Fast MRI Reconstruction21 Jun 2024
- 2024INFusion: Diffusion Regularized Implicit Neural Representations for 2D and 3D accelerated MRI reconstruction19 Jun 2024
- 2024Autoregressive Image Diffusion: Generation of Image Sequence and Application in MRI23 May 2024
- 2024Noise Level Adaptive Diffusion Model for Robust Reconstruction of Accelerated MRI8 Mar 2024
- 2024On the Challenges and Opportunities in Generative AI28 Feb 2024
- 2023A Survey of Emerging Applications of Diffusion Probabilistic Models in MRI19 Nov 2023
- 2023Bias-Reduced Neural Networks for Parameter Estimation in Quantitative MRI13 Nov 2023
- 2023Joint Non-Linear MRI Inversion with Diffusion Priors23 Oct 2023
- 2023Investigating the Adversarial Robustness of Density Estimation Using the Probability Flow ODE10 Oct 2023
- 2023A review of uncertainty quantification in medical image analysis: probabilistic and non-probabilistic methods9 Oct 2023
- 2023The Emergence of Reproducibility and Generalizability in Diffusion Models8 Oct 2023
- 2023Correlated and Multi-frequency Diffusion Modeling for Highly Under-sampled MRI Reconstruction2 Sep 2023
- 2023Diffusion Modeling with Domain-conditioned Prior Guidance for Accelerated MRI and qMRI Reconstruction2 Sep 2023
- 2023Generative Priors for MRI Reconstruction Trained from Magnitude-Only Images Using Phase Augmentation4 Aug 2023
- 2023Learning Fourier-Constrained Diffusion Bridges for MRI Reconstruction2 Aug 2023
- 2023Solving Inverse Problems with Score-Based Generative Priors learned from Noisy Data2 May 2023
- 2023MRI Reconstruction with Side Information using Diffusion Models26 Mar 2023
- 2023Decomposed Diffusion Sampler for Accelerating Large-Scale Inverse Problems10 Mar 2023
- 2023PixCUE: Joint Uncertainty Estimation and Image Reconstruction in MRI using Deep Pixel Classification28 Feb 2023
- 2022Stable Deep MRI Reconstruction using Generative Priors25 Oct 2022
- 2022One-shot Generative Prior in Hankel-k-space for Parallel Imaging Reconstruction15 Aug 2022
- 2023Decomposed Diffusion Sampler for Accelerating Large-Scale Inverse Problemscited by 129
- 2025InverseBench: Benchmarking Plug-and-Play Diffusion Priors for Inverse Problems in Physical Sciencescited by 67
- 2023Solving Inverse Problems with Score-Based Generative Priors learned from Noisy Datacited by 40
- 2023The Emergence of Reproducibility and Generalizability in Diffusion Modelscited by 21
- 2023Diffusion Modeling with Domain-conditioned Prior Guidance for Accelerated MRI and qMRI Reconstructioncited by 20
- 2023MRI Reconstruction with Side Information using Diffusion Modelscited by 15
- 2023Correlated and Multi-frequency Diffusion Modeling for Highly Under-sampled MRI Reconstructioncited by 14
- 2023Learning Fourier-Constrained Diffusion Bridges for MRI Reconstructioncited by 13
- 2023A Survey of Emerging Applications of Diffusion Probabilistic Models in MRIcited by 9
- 2024Self-Supervised Adversarial Diffusion Models for Fast MRI Reconstructioncited by 9
- 2024Noise Level Adaptive Diffusion Model for Robust Reconstruction of Accelerated MRIcited by 6
- 2024Highly Accelerated MRI via Implicit Neural Representation Guided Posterior Sampling of Diffusion Modelscited by 5
12 most cited of 28 All 28 (JSON)
- 2026Uncertainty-Aware 3D Residual Wavelet Diffusion for Ultra Low-Field MRI Super-Resolution21 Sep 2026
- 2026Consistency Models for Fast MRI Reconstruction Using Regularization by Denoising20 Aug 2026
- 2026Product-of-Gaussian-Mixture Diffusion Models for Joint Nonlinear MRI Reconstruction11 May 2026
- 2026Accelerating Stroke MRI with Diffusion Probabilistic Models through Large-Scale Pre-training and Target-Specific Fine-Tuning13 Mar 2026
- 2026Beyond Accuracy: Evaluating Posterior Fidelity of Diffusion Inverse Solvers4 Feb 2026
- 2025Fast and Robust Diffusion Posterior Sampling for MR Image Reconstruction Using the Preconditioned Unadjusted Langevin Algorithm5 Dec 2025
- 2025Antithetic Noise in Diffusion Models6 Jun 2025
- 2025Diffusion Probabilistic Generative Models for Accelerated, in-NICU Permanent Magnet Neonatal MRI21 May 2025
- 2025Unsupervised Radar Point Cloud Enhancement via Arbitrary LiDAR Guided Diffusion Prior15 May 2025
- 2025InverseBench: Benchmarking Plug-and-Play Diffusion Priors for Inverse Problems in Physical Sciences14 Mar 2025
- 2024Sub-DM:Subspace Diffusion Model with Orthogonal Decomposition for MRI Reconstruction6 Nov 2024
- 2024Denoising Diffusion Probabilistic Models for Magnetic Resonance Fingerprinting29 Oct 2024
12 newest of 28 All 28 (JSON)
- 2023A review of uncertainty quantification in medical image analysis: probabilistic and non-probabilistic methodscited by 39
- 2024On the Challenges and Opportunities in Generative AIcited by 31
- 2022Stable Deep MRI Reconstruction using Generative Priorscited by 21
- 2022One-shot Generative Prior in Hankel-k-space for Parallel Imaging Reconstructioncited by 11
- 2025Diffusion at Absolute Zero: Langevin Sampling Using Successive Moreau Envelopes [conference paper]cited by 6
- 2024Autoregressive Image Diffusion: Generation of Image Sequence and Application in MRIcited by 4
- 2024Robust multi-coil MRI reconstruction via self-supervised denoisingcited by 4
- 2025Self-diffusion for Solving Inverse Problemscited by 4
- 2023PixCUE: Joint Uncertainty Estimation and Image Reconstruction in MRI using Deep Pixel Classificationcited by 3
- 2023Generative Priors for MRI Reconstruction Trained from Magnitude-Only Images Using Phase Augmentationcited by 3
- 2024Fast MRI for All: Bridging Access Gaps by Training without Raw Datacited by 2
- 2025How many measurements are enough? Bayesian recovery in inverse problems with general distributionscited by 2
12 most cited of 18 All 18 (JSON)
- 2026MUST: Modality-Specific Representation-Aware Transformer for Diffusion-Enhanced Survival Prediction with Missing Modality27 Mar 2026
- 2026CARE: Training-Free Controllable Restoration for Medical Images via Dual-Latent Steering26 Mar 2026
- 2026MRI2Qmap: multi-parametric quantitative mapping with MRI-driven denoising priors11 Mar 2026
- 2025Self-diffusion for Solving Inverse Problems24 Oct 2025
- 2025How many measurements are enough? Bayesian recovery in inverse problems with general distributions15 May 2025
- 2025A Comprehensive Survey on Magnetic Resonance Image Reconstruction10 Mar 2025
- 2025Guiding Quantitative MRI Reconstruction with Phase-wise Uncertainty28 Feb 2025
- 2025Diffusion at Absolute Zero: Langevin Sampling Using Successive Moreau Envelopes [conference paper]3 Feb 2025
- 2024Fast MRI for All: Bridging Access Gaps by Training without Raw Data20 Nov 2024
- 2024Robust multi-coil MRI reconstruction via self-supervised denoising19 Nov 2024
- 2024Autoregressive Image Diffusion: Generation of Image Sequence and Application in MRI23 May 2024
- 2024On the Challenges and Opportunities in Generative AI28 Feb 2024
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