Towards performant and reliable undersampled MR reconstruction via diffusion model sampling
On the map: Diffusion models → Medical imaging and segmentation
Abstract (arXiv)
Magnetic Resonance (MR) image reconstruction from under-sampled acquisition promises faster scanning time. To this end, current State-of-The-Art (SoTA) approaches leverage deep neural networks and supervised training to learn a recovery model. While these approaches achieve impressive performances, the learned model can be fragile on unseen degradation, e.g. when given a different acceleration factor. These methods are also generally deterministic and provide a single solution to an ill-posed problem; as such, it can be difficult for practitioners to understand the reliability of the reconstruction. We introduce DiffuseRecon, a novel diffusion model-based MR reconstruction method. DiffuseRecon guides the generation process based on the observed signals and a pre-trained diffusion model, and does not require additional training on specific acceleration factors. DiffuseRecon is stochastic in nature and generates results from a distribution of fully-sampled MR images; as such, it allows us to explicitly visualize different potential reconstruction solutions. Lastly, DiffuseRecon proposes an accelerated, coarse-to-fine Monte-Carlo sampling scheme to approximate the most likely reconstruction candidate. The proposed DiffuseRecon achieves SoTA performances reconstructing from raw acquisition signals in fastMRI and SKM-TEA. Code will be open-sourced at www.github.com/cpeng93/DiffuseRecon.
Key facts. Cited by 59 papers in the map (data through 7 Oct 2026). Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models. Builds on 16 of its 25 references that are in the map. First posted on arXiv 8 Mar 2022.
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Other references · 15
- 2020Denoising Diffusion Probabilistic Modelscited by 20,851
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
- 2020Denoising Diffusion Implicit Modelscited by 9,655
- 2021Diffusion Models Beat GANs on Image Synthesiscited by 8,185
- 2021Improved Denoising Diffusion Probabilistic Modelscited by 3,736
- 2018fastMRI: An Open Dataset and Benchmarks for Accelerated MRIcited by 464
- 2017Learning a Variational Network for Reconstruction of Accelerated MRI Datacited by 340
- 2017A Deep Cascade of Convolutional Neural Networks for Dynamic MR Image Reconstructioncited by 231
- 2021On Fast Sampling of Diffusion Probabilistic Modelscited by 170
- 2017Convolutional Recurrent Neural Networks for Dynamic MR Image Reconstructioncited by 105
- 2021Multi-institutional Collaborations for Improving Deep Learning-based Magnetic Resonance Image Reconstruction Using Federated Learningcited by 78
- 2020DuDoRNet: Learning a Dual-Domain Recurrent Network for Fast MRI Reconstruction with Deep T1 Priorcited by 72
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Citing papers per year: 2022: 4; 2023: 19; 2024: 24; 2025: 9; 2026: 3.
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- 2022Diffusion Models: A Comprehensive Survey of Methods and Applicationscited by 1,107
- 2022Diffusion Models for Medical Image Analysis: A Comprehensive Surveycited by 269
- 2022GENIE: Higher-Order Denoising Diffusion Solverscited by 127
- 2022Adaptive Diffusion Priors for Accelerated MRI Reconstructioncited by 117
- 2024MAISI: Medical AI for Synthetic Imagingcited by 86
- 2024Diffusion Models in Low-Level Vision: A Surveycited by 73
- 2023On the Design Fundamentals of Diffusion Models: A Surveycited by 59
- 2023Self-Supervised MRI Reconstruction with Unrolled Diffusion Modelscited by 37
- 2024Rethinking Diffusion Model for Multi-Contrast MRI Super-Resolutioncited by 29
- 2024Self-Consistent Recursive Diffusion Bridge for Medical Image Translationcited by 26
- 2023Uncertainty-aware Surrogate Models for Airfoil Flow Simulations with Denoising Diffusion Probabilistic Modelscited by 22
- 2023Diffusion Probabilistic Priors for Zero-Shot Low-Dose CT Image Denoisingcited by 21
38 more
- 2023Diffusion Modeling with Domain-conditioned Prior Guidance for Accelerated MRI and qMRI Reconstructioncited by 20
- 2024DPER: Diffusion Prior Driven Neural Representation for Limited Angle and Sparse View CT Reconstructioncited by 17
- 2023Learning Fourier-Constrained Diffusion Bridges for MRI Reconstructioncited by 13
- 2025Text2CT: Towards 3D CT Volume Generation from Free-text Descriptions Using Diffusion Modelcited by 13
- 2023SPIRiT-Diffusion: Self-Consistency Driven Diffusion Model for Accelerated MRIcited by 12
- 2025Metrics that matter: Evaluating image quality metrics for medical image generationcited by 12
- 2023CDiffMR: Can We Replace the Gaussian Noise with K-Space Undersampling for Fast MRI?cited by 11
- 2023DDMM-Synth: A Denoising Diffusion Model for Cross-modal Medical Image Synthesis with Sparse-view Measurement Embeddingcited by 10
- 2023Uncertainty Estimation and Propagation in Accelerated MRI Reconstructioncited by 10
- 2023DiffuseIR:Diffusion Models For Isotropic Reconstruction of 3D Microscopic Imagescited by 9
- 2023A Survey of Emerging Applications of Diffusion Probabilistic Models in MRIcited by 9
- 2023Fast Controllable Diffusion Models for Undersampled MRI Reconstructioncited by 8
- 2024TC-DiffRecon: Texture coordination MRI reconstruction method based on diffusion model and modified MF-UNet methodcited by 5
- 2024Stability and Generalizability in SDE Diffusion Models with Measure-Preserving Dynamicscited by 5
- 2024Highly Accelerated MRI via Implicit Neural Representation Guided Posterior Sampling of Diffusion Modelscited by 5
- 2023Robust Physics-based Deep MRI Reconstruction Via Diffusion Purificationcited by 4
- 2023Robust semi-supervised segmentation with timestep ensembling diffusion modelscited by 4
- 2024RadGazeGen: Radiomics and Gaze-guided Medical Image Generation using Diffusion Modelscited by 4
- 2024MRPD: Undersampled MRI reconstruction by prompting a large latent diffusion modelcited by 3
- 2024Score-based Generative Priors Guided Model-driven Network for MRI Reconstructioncited by 3
- 2024Denoising Diffusion Probabilistic Models for Magnetic Resonance Fingerprintingcited by 3
- 2025DH-Mamba: Exploring Dual-domain Hierarchical State Space Models for MRI Reconstructioncited by 3
- 2025Reconstruct or Generate: Exploring the Spectrum of Generative Modeling for Cardiac MRIcited by 3
- 2023Learning Enhancement From Degradation: A Diffusion Model For Fundus Image Enhancementcited by 2
- 2023Constrained Probabilistic Mask Learning for Task-specific Undersampled MRI Reconstructioncited by 2
- 2024A Flow-based Truncated Denoising Diffusion Model for Super-resolution Magnetic Resonance Spectroscopic Imagingcited by 2
- 2024Sub-DM:Subspace Diffusion Model with Orthogonal Decomposition for MRI Reconstructioncited by 2
- 2025Physics informed guided diffusion for accelerated multi-parametric MRI reconstructioncited by 2
- 2023Improving Denoising Diffusion Probabilistic Models via Exploiting Shared Representationscited by 1
- 2024DuDoUniNeXt: Dual-domain unified hybrid model for single and multi-contrast undersampled MRI reconstructioncited by 1
- 2024Clinically Feasible Diffusion Reconstruction for Highly-Accelerated Cardiac Cine MRIcited by 1
- 2024Spatiotemporal Diffusion Model with Paired Sampling for Accelerated Cardiac Cine MRIcited by 1
- 2024Structural and Convergence Analysis of Discrete-Time Denoising Diffusion Probabilistic Modelscited by 1
- 2024Guided MRI Reconstruction via Schr"odinger Bridgecited by 1
- 2024Self-Consistent Nested Diffusion Bridge for Accelerated MRI Reconstructioncited by 1
- 2025A Comprehensive Survey on Magnetic Resonance Image Reconstructioncited by 1
- 2025Computationally Efficient Diffusion Models in Medical Imaging: A Comprehensive Reviewcited by 1
- 2025USB: Unified Synthetic Brain Framework for Bidirectional Pathology-Healthy Generation and Editingcited by 1
50 most cited of 59 All 59 (JSON)
- 2026Measured-Subspace Consistency: A Plug-and-Play Operator for Diffusion Posterior Sampling in Accelerated MRI Reconstruction26 Jun 2026
- 2026Variational Network with Wavelet-based UNET in Accelerated MRI Reconstruction from Under Sampled K-space Data13 Jun 2026
- 2026Next-Acceleration-Scale Prediction for Autoregressive MRI Reconstruction19 May 2026
- 2025USB: Unified Synthetic Brain Framework for Bidirectional Pathology-Healthy Generation and Editing29 Nov 2025
- 2025Predicting before Reconstruction: A generative prior framework for MRI acceleration22 Oct 2025
- 2025Reconstruct or Generate: Exploring the Spectrum of Generative Modeling for Cardiac MRI25 Jul 2025
- 2025Physics informed guided diffusion for accelerated multi-parametric MRI reconstruction29 Jun 2025
- 2025Metrics that matter: Evaluating image quality metrics for medical image generation12 May 2025
- 2025Computationally Efficient Diffusion Models in Medical Imaging: A Comprehensive Review9 May 2025
- 2025Text2CT: Towards 3D CT Volume Generation from Free-text Descriptions Using Diffusion Model7 May 2025
- 2025A Comprehensive Survey on Magnetic Resonance Image Reconstruction10 Mar 2025
- 2025DH-Mamba: Exploring Dual-domain Hierarchical State Space Models for MRI Reconstruction14 Jan 2025
38 more
- 2024Self-Consistent Nested Diffusion Bridge for Accelerated MRI Reconstruction13 Dec 2024
- 2024Guided MRI Reconstruction via Schr"odinger Bridge21 Nov 2024
- 2024Sub-DM:Subspace Diffusion Model with Orthogonal Decomposition for MRI Reconstruction6 Nov 2024
- 2024LDPM: Towards undersampled MRI reconstruction with MR-VAE and Latent Diffusion Prior5 Nov 2024
- 2024MS-Glance: Bio-Insipred Non-semantic Context Vectors and their Applications in Supervising Image Reconstruction31 Oct 2024
- 2024Denoising Diffusion Probabilistic Models for Magnetic Resonance Fingerprinting29 Oct 2024
- 2024A Flow-based Truncated Denoising Diffusion Model for Super-resolution Magnetic Resonance Spectroscopic Imaging25 Oct 2024
- 2024RadGazeGen: Radiomics and Gaze-guided Medical Image Generation using Diffusion Models1 Oct 2024
- 2024Sampling-Pattern-Agnostic MRI Reconstruction through Adaptive Consistency Enforcement with Diffusion Model22 Sep 2024
- 2024MAISI: Medical AI for Synthetic Imaging13 Sep 2024
- 2024TC-KANRecon: High-Quality and Accelerated MRI Reconstruction via Adaptive KAN Mechanisms and Intelligent Feature Scaling11 Aug 2024
- 2024Highly Accelerated MRI via Implicit Neural Representation Guided Posterior Sampling of Diffusion Models3 Jul 2024
- 2024Stability and Generalizability in SDE Diffusion Models with Measure-Preserving Dynamics19 Jun 2024
- 2024Diffusion Models in Low-Level Vision: A Survey17 Jun 2024
- 2024Structural and Convergence Analysis of Discrete-Time Denoising Diffusion Probabilistic Models3 Jun 2024
- 2024Self-Consistent Recursive Diffusion Bridge for Medical Image Translation10 May 2024
- 2024Score-based Generative Priors Guided Model-driven Network for MRI Reconstruction5 May 2024
- 2024DPER: Diffusion Prior Driven Neural Representation for Limited Angle and Sparse View CT Reconstruction27 Apr 2024
- 2024Rethinking Diffusion Model for Multi-Contrast MRI Super-Resolution7 Apr 2024
- 2024Spatiotemporal Diffusion Model with Paired Sampling for Accelerated Cardiac Cine MRI13 Mar 2024
- 2024Clinically Feasible Diffusion Reconstruction for Highly-Accelerated Cardiac Cine MRI13 Mar 2024
- 2024DuDoUniNeXt: Dual-domain unified hybrid model for single and multi-contrast undersampled MRI reconstruction8 Mar 2024
- 2024TC-DiffRecon: Texture coordination MRI reconstruction method based on diffusion model and modified MF-UNet method17 Feb 2024
- 2024MRPD: Undersampled MRI reconstruction by prompting a large latent diffusion model16 Feb 2024
- 2023Uncertainty-aware Surrogate Models for Airfoil Flow Simulations with Denoising Diffusion Probabilistic Models8 Dec 2023
- 2023Improving Denoising Diffusion Probabilistic Models via Exploiting Shared Representations27 Nov 2023
- 2023Masked Conditional Diffusion Models for Image Analysis with Application to Radiographic Diagnosis of Infant Abuse22 Nov 2023
- 2023Fast Controllable Diffusion Models for Undersampled MRI Reconstruction20 Nov 2023
- 2023A Survey of Emerging Applications of Diffusion Probabilistic Models in MRI19 Nov 2023
- 2023Robust semi-supervised segmentation with timestep ensembling diffusion models13 Nov 2023
- 2023Robust Physics-based Deep MRI Reconstruction Via Diffusion Purification11 Sep 2023
- 2023Diffusion Modeling with Domain-conditioned Prior Guidance for Accelerated MRI and qMRI Reconstruction2 Sep 2023
- 2023Uncertainty Estimation and Propagation in Accelerated MRI Reconstruction4 Aug 2023
- 2023Learning Fourier-Constrained Diffusion Bridges for MRI Reconstruction2 Aug 2023
- 2023Self-Supervised MRI Reconstruction with Unrolled Diffusion Models29 Jun 2023
- 2023CDiffMR: Can We Replace the Gaussian Noise with K-Space Undersampling for Fast MRI?25 Jun 2023
- 2023DiffuseIR:Diffusion Models For Isotropic Reconstruction of 3D Microscopic Images21 Jun 2023
- 2023On the Design Fundamentals of Diffusion Models: A Survey7 Jun 2023
50 newest of 59 All 59 (JSON)
- 2022Diffusion Models: A Comprehensive Survey of Methods and Applicationscited by 1,107
- 2022Diffusion Models for Medical Image Analysis: A Comprehensive Surveycited by 269
- 2022GENIE: Higher-Order Denoising Diffusion Solverscited by 127
- 2022Adaptive Diffusion Priors for Accelerated MRI Reconstructioncited by 117
- 2024MAISI: Medical AI for Synthetic Imagingcited by 86
- 2024Diffusion Models in Low-Level Vision: A Surveycited by 73
- 2023On the Design Fundamentals of Diffusion Models: A Surveycited by 59
- 2023Self-Supervised MRI Reconstruction with Unrolled Diffusion Modelscited by 37
- 2024Rethinking Diffusion Model for Multi-Contrast MRI Super-Resolutioncited by 29
- 2024Self-Consistent Recursive Diffusion Bridge for Medical Image Translationcited by 26
- 2023Uncertainty-aware Surrogate Models for Airfoil Flow Simulations with Denoising Diffusion Probabilistic Modelscited by 22
- 2023Diffusion Probabilistic Priors for Zero-Shot Low-Dose CT Image Denoisingcited by 21
12 most cited of 44 All 44 (JSON)
- 2025Reconstruct or Generate: Exploring the Spectrum of Generative Modeling for Cardiac MRI25 Jul 2025
- 2025Physics informed guided diffusion for accelerated multi-parametric MRI reconstruction29 Jun 2025
- 2025Computationally Efficient Diffusion Models in Medical Imaging: A Comprehensive Review9 May 2025
- 2025Text2CT: Towards 3D CT Volume Generation from Free-text Descriptions Using Diffusion Model7 May 2025
- 2024Self-Consistent Nested Diffusion Bridge for Accelerated MRI Reconstruction13 Dec 2024
- 2024Sub-DM:Subspace Diffusion Model with Orthogonal Decomposition for MRI Reconstruction6 Nov 2024
- 2024LDPM: Towards undersampled MRI reconstruction with MR-VAE and Latent Diffusion Prior5 Nov 2024
- 2024Denoising Diffusion Probabilistic Models for Magnetic Resonance Fingerprinting29 Oct 2024
- 2024A Flow-based Truncated Denoising Diffusion Model for Super-resolution Magnetic Resonance Spectroscopic Imaging25 Oct 2024
- 2024RadGazeGen: Radiomics and Gaze-guided Medical Image Generation using Diffusion Models1 Oct 2024
- 2024Sampling-Pattern-Agnostic MRI Reconstruction through Adaptive Consistency Enforcement with Diffusion Model22 Sep 2024
- 2024MAISI: Medical AI for Synthetic Imaging13 Sep 2024
12 newest of 44 All 44 (JSON)
- 2025Metrics that matter: Evaluating image quality metrics for medical image generationcited by 12
- 2023Uncertainty Estimation and Propagation in Accelerated MRI Reconstructioncited by 10
- 2024Score-based Generative Priors Guided Model-driven Network for MRI Reconstructioncited by 3
- 2023Constrained Probabilistic Mask Learning for Task-specific Undersampled MRI Reconstructioncited by 2
- 2024DuDoUniNeXt: Dual-domain unified hybrid model for single and multi-contrast undersampled MRI reconstructioncited by 1
- 2024Guided MRI Reconstruction via Schr"odinger Bridgecited by 1
- 2025A Comprehensive Survey on Magnetic Resonance Image Reconstructioncited by 1
- 2025USB: Unified Synthetic Brain Framework for Bidirectional Pathology-Healthy Generation and Editingcited by 1
- 2024TC-KANRecon: High-Quality and Accelerated MRI Reconstruction via Adaptive KAN Mechanisms and Intelligent Feature Scalingcited by 0
- 2024MS-Glance: Bio-Insipred Non-semantic Context Vectors and their Applications in Supervising Image Reconstructioncited by 0
- 2025Predicting before Reconstruction: A generative prior framework for MRI accelerationcited by 0
- 2026Next-Acceleration-Scale Prediction for Autoregressive MRI Reconstructioncited by 0
12 most cited of 14 All 14 (JSON)
- 2026Measured-Subspace Consistency: A Plug-and-Play Operator for Diffusion Posterior Sampling in Accelerated MRI Reconstruction26 Jun 2026
- 2026Variational Network with Wavelet-based UNET in Accelerated MRI Reconstruction from Under Sampled K-space Data13 Jun 2026
- 2026Next-Acceleration-Scale Prediction for Autoregressive MRI Reconstruction19 May 2026
- 2025USB: Unified Synthetic Brain Framework for Bidirectional Pathology-Healthy Generation and Editing29 Nov 2025
- 2025Predicting before Reconstruction: A generative prior framework for MRI acceleration22 Oct 2025
- 2025Metrics that matter: Evaluating image quality metrics for medical image generation12 May 2025
- 2025A Comprehensive Survey on Magnetic Resonance Image Reconstruction10 Mar 2025
- 2024Guided MRI Reconstruction via Schr"odinger Bridge21 Nov 2024
- 2024MS-Glance: Bio-Insipred Non-semantic Context Vectors and their Applications in Supervising Image Reconstruction31 Oct 2024
- 2024TC-KANRecon: High-Quality and Accelerated MRI Reconstruction via Adaptive KAN Mechanisms and Intelligent Feature Scaling11 Aug 2024
- 2024Score-based Generative Priors Guided Model-driven Network for MRI Reconstruction5 May 2024
- 2024DuDoUniNeXt: Dual-domain unified hybrid model for single and multi-contrast undersampled MRI reconstruction8 Mar 2024
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