Boundary Difference Over Union Loss For Medical Image Segmentation
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Abstract (arXiv)
Medical image segmentation is crucial for clinical diagnosis. However, current losses for medical image segmentation mainly focus on overall segmentation results, with fewer losses proposed to guide boundary segmentation. Those that do exist often need to be used in combination with other losses and produce ineffective results. To address this issue, we have developed a simple and effective loss called the Boundary Difference over Union Loss (Boundary DoU Loss) to guide boundary region segmentation. It is obtained by calculating the ratio of the difference set of prediction and ground truth to the union of the difference set and the partial intersection set. Our loss only relies on region calculation, making it easy to implement and training stable without needing any additional losses. Additionally, we use the target size to adaptively adjust attention applied to the boundary regions. Experimental results using UNet, TransUNet, and Swin-UNet on two datasets (ACDC and Synapse) demonstrate the effectiveness of our proposed loss function. Code is available at https://github.com/sunfan-bvb/BoundaryDoULoss.
Key facts. Cited by 13 papers in the map (data through 14 Oct 2026). Builds on 22 of its 25 references that are in the map. First posted on arXiv 1 Aug 2023.
Builds on
22 of 25 references.
References · 22
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,713
- 2017Mask R-CNNcited by 7,277
- 2014Fully Convolutional Networks for Semantic Segmentationcited by 4,859
- 2018Encoder-Decoder with Atrous Separable Convolution for Semantic Image Segmentationcited by 3,223
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10 more
- 2017Generalised Dice overlap as a deep learning loss function for highly unbalanced segmentationscited by 620
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Citing papers per year: 2023: 2; 2024: 1; 2025: 4; 2026: 6.
13 papers.
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- 2023Loss Functions in the Era of Semantic Segmentation: A Survey and Outlookcited by 34
- 2024Centerline Boundary Dice Loss for Vascular Segmentationcited by 27
- 2023SAMIHS: Adaptation of Segment Anything Model for Intracranial Hemorrhage Segmentationcited by 5
- 2025CENet: Context Enhancement Network for Medical Image Segmentationcited by 5
- 2025Rethinking Boundary Detection in Deep Learning-Based Medical Image Segmentationcited by 2
- 2025SoftPQ: Robust Instance Segmentation Evaluation via Soft Matching and Tunable Thresholdscited by 1
- 2025Uncertainty-Gated Deformable Network for Breast Tumor Segmentation in MR Imagescited by 0
- 2026PBE-UNet: A light weight Progressive Boundary-Enhanced U-Net with Scale-Aware Aggregation for Ultrasound Image Segmentationcited by 0
- 2026Augmented Equivariant Mesh Networks for Anatomical Segmentationcited by 0
- 2026Learning a Sampling-Free Variational DNN Plugin from Tiny Training Sets to Refine OOD Segmentation With Uncertainty Estimationcited by 0
- 2026Specificity- and Calibration-Aware Breast Ultrasound Segmentation via Entropy-Guided Boundary Supervisioncited by 0
- 2026Towards Voxel Spacing Consistency for Medical Image Segmentationcited by 0
- 2026Unsupervised Adversarial Domain Adaptation for Uterine layer Segmentation: From Labeled Cine to Unlabeled Dynamic EPI MRI4 Aug 2026
- 2026Towards Voxel Spacing Consistency for Medical Image Segmentation30 Jun 2026
- 2026Specificity- and Calibration-Aware Breast Ultrasound Segmentation via Entropy-Guided Boundary Supervision21 Jun 2026
- 2026Learning a Sampling-Free Variational DNN Plugin from Tiny Training Sets to Refine OOD Segmentation With Uncertainty Estimation14 Jun 2026
- 2026Augmented Equivariant Mesh Networks for Anatomical Segmentation4 May 2026
- 2026PBE-UNet: A light weight Progressive Boundary-Enhanced U-Net with Scale-Aware Aggregation for Ultrasound Image Segmentation15 Apr 2026
- 2025Uncertainty-Gated Deformable Network for Breast Tumor Segmentation in MR Images19 Sep 2025
- 2025CENet: Context Enhancement Network for Medical Image Segmentation23 May 2025
- 2025SoftPQ: Robust Instance Segmentation Evaluation via Soft Matching and Tunable Thresholds17 May 2025
- 2025Rethinking Boundary Detection in Deep Learning-Based Medical Image Segmentation6 May 2025
- 2024Centerline Boundary Dice Loss for Vascular Segmentation1 Jul 2024
- 2023Loss Functions in the Era of Semantic Segmentation: A Survey and Outlook8 Dec 2023
- 2023Loss Functions in the Era of Semantic Segmentation: A Survey and Outlookcited by 34
- 2024Centerline Boundary Dice Loss for Vascular Segmentationcited by 27
- 2023SAMIHS: Adaptation of Segment Anything Model for Intracranial Hemorrhage Segmentationcited by 5
- 2025CENet: Context Enhancement Network for Medical Image Segmentationcited by 5
- 2025Rethinking Boundary Detection in Deep Learning-Based Medical Image Segmentationcited by 2
- 2025SoftPQ: Robust Instance Segmentation Evaluation via Soft Matching and Tunable Thresholdscited by 1
- 2025Uncertainty-Gated Deformable Network for Breast Tumor Segmentation in MR Imagescited by 0
- 2026PBE-UNet: A light weight Progressive Boundary-Enhanced U-Net with Scale-Aware Aggregation for Ultrasound Image Segmentationcited by 0
- 2026Augmented Equivariant Mesh Networks for Anatomical Segmentationcited by 0
- 2026Learning a Sampling-Free Variational DNN Plugin from Tiny Training Sets to Refine OOD Segmentation With Uncertainty Estimationcited by 0
- 2026Specificity- and Calibration-Aware Breast Ultrasound Segmentation via Entropy-Guided Boundary Supervisioncited by 0
- 2026Towards Voxel Spacing Consistency for Medical Image Segmentationcited by 0
12 most cited of 13 All 13 (JSON)
- 2026Unsupervised Adversarial Domain Adaptation for Uterine layer Segmentation: From Labeled Cine to Unlabeled Dynamic EPI MRI4 Aug 2026
- 2026Towards Voxel Spacing Consistency for Medical Image Segmentation30 Jun 2026
- 2026Specificity- and Calibration-Aware Breast Ultrasound Segmentation via Entropy-Guided Boundary Supervision21 Jun 2026
- 2026Learning a Sampling-Free Variational DNN Plugin from Tiny Training Sets to Refine OOD Segmentation With Uncertainty Estimation14 Jun 2026
- 2026Augmented Equivariant Mesh Networks for Anatomical Segmentation4 May 2026
- 2026PBE-UNet: A light weight Progressive Boundary-Enhanced U-Net with Scale-Aware Aggregation for Ultrasound Image Segmentation15 Apr 2026
- 2025Uncertainty-Gated Deformable Network for Breast Tumor Segmentation in MR Images19 Sep 2025
- 2025CENet: Context Enhancement Network for Medical Image Segmentation23 May 2025
- 2025SoftPQ: Robust Instance Segmentation Evaluation via Soft Matching and Tunable Thresholds17 May 2025
- 2025Rethinking Boundary Detection in Deep Learning-Based Medical Image Segmentation6 May 2025
- 2024Centerline Boundary Dice Loss for Vascular Segmentation1 Jul 2024
- 2023Loss Functions in the Era of Semantic Segmentation: A Survey and Outlook8 Dec 2023
12 newest of 13 All 13 (JSON)