Cutting-edge 3D Medical Image Segmentation Methods in 2020: Are Happy Families All Alike?
Not on the map. Why?
Abstract (arXiv)
Segmentation is one of the most important and popular tasks in medical image analysis, which plays a critical role in disease diagnosis, surgical planning, and prognosis evaluation. During the past five years, on the one hand, thousands of medical image segmentation methods have been proposed for various organs and lesions in different medical images, which become more and more challenging to fairly compare different methods. On the other hand, international segmentation challenges can provide a transparent platform to fairly evaluate and compare different methods. In this paper, we present a comprehensive review of the top methods in ten 3D medical image segmentation challenges during 2020, covering a variety of tasks and datasets. We also identify the "happy-families" practices in the cutting-edge segmentation methods, which are useful for developing powerful segmentation approaches. Finally, we discuss open research problems that should be addressed in the future. We also maintain a list of cutting-edge segmentation methods at urlhttps://github.com/JunMa11/SOTA-MedSeg.
Key facts. Cited by 7 papers in the map (data through 14 Oct 2026). Builds on 42 of its 64 references that are in the map. First posted on arXiv 1 Jan 2021.
Builds on
42 of 64 references.
References · 42
- 2014Adam: A Method for Stochastic Optimizationcited by 37,240
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,713
- 2016V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentationcited by 2,292
- 20163D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotationcited by 1,476
- 2018Continual Lifelong Learning with Neural Networks: A Reviewcited by 1,330
- 2017A Survey on Deep Learning in Medical Image Analysiscited by 1,186
- 2020Image Segmentation Using Deep Learning: A Surveycited by 660
- 2018Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challengecited by 511
- 2019Selective Kernel Networkscited by 403
- 2019Embracing Imperfect Datasets: A Review of Deep Learning Solutions for Medical Image Segmentationcited by 260
- 2017Tversky loss function for image segmentation using 3D fully convolutional deep networkscited by 228
- 2020AbdomenCT-1K: Is Abdominal Organ Segmentation A Solved Problem?cited by 224
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- 2018Online Learning: A Comprehensive Surveycited by 205
- 2018Boundary loss for highly unbalanced segmentationcited by 190
- 2018Not-so-supervised: a survey of semi-supervised, multi-instance, and transfer learning in medical image analysiscited by 179
- 2019Deep learning with noisy labels: exploring techniques and remedies in medical image analysiscited by 173
- 2016Multivariate mixture model for myocardium segmentation combining multi-source imagescited by 133
- 2016The Importance of Skip Connections in Biomedical Image Segmentationcited by 126
- 2020nnU-Net for Brain Tumor Segmentationcited by 103
- 2020Towards a Mathematical Understanding of Neural Network-Based Machine Learning: what we know and what we don'tcited by 95
- 2019Integrating Spatial Configuration into Heatmap Regression Based CNNs for Landmark Localizationcited by 77
- 2019Theoretical Issues in Deep Networks: Approximation, Optimization and Generalizationcited by 72
- 2019Small Data Challenges in Big Data Era: A Survey of Recent Progress on Unsupervised and Semi-Supervised Methodscited by 62
- 2019BIAS: Transparent reporting of biomedical image analysis challengescited by 57
- 2020Towards Data-Efficient Learning: A Benchmark for COVID-19 CT Lung and Infection Segmentationcited by 53
- 2019Deep Distance Transform for Tubular Structure Segmentation in CT Scanscited by 52
- 2020Recent advances in deep learning theorycited by 41
- 2017Born to Learn: the Inspiration, Progress, and Future of Evolved Plastic Artificial Neural Networkscited by 29
- 2020Studying Robustness of Semantic Segmentation under Domain Shift in cardiac MRIcited by 28
- 2020Modality-Pairing Learning for Brain Tumor Segmentationcited by 17
- 2020AGE Challenge: Angle Closure Glaucoma Evaluation in Anterior Segment Optical Coherence Tomographycited by 15
- 2020Histogram Matching Augmentation for Domain Adaptation with Application to Multi-Centre, Multi-Vendor and Multi-Disease Cardiac Image Segmentationcited by 12
- 2020Cascaded Convolutional Neural Network for Automatic Myocardial Infarction Segmentation from Delayed-Enhancement Cardiac MRIcited by 12
- 2016An efficient iterative thresholding method for image segmentationcited by 10
- 2020Semi-supervised Cardiac Image Segmentation via Label Propagation and Style Transfercited by 10
- 2020H2NF-Net for Brain Tumor Segmentation using Multimodal MR Imaging: 2nd Place Solution to BraTS Challenge 2020 Segmentation Taskcited by 10
- 2019The iterative convolution-thresholding method (ICTM) for image segmentationcited by 9
- 2020Segmentation Loss Odysseycited by 7
- 2020Cascaded Framework for Automatic Evaluation of Myocardial Infarction from Delayed-Enhancement Cardiac MRIcited by 5
- 2020Ensembled ResUnet for Anatomical Brain Barriers Segmentationcited by 4
- 2020Combining CNN and Hybrid Active Contours for Head and Neck Tumor Segmentation in CT and PET imagescited by 3
- 2020Exploring Large Context for Cerebral Aneurysm Segmentationcited by 2
Built on by
Citing papers per year: 2021: 1; 2022: 3; 2023: 0; 2024: 2; 2025: 1.
7 papers.
- 2021The Medical Segmentation Decathloncited by 628
- 2024U-Mamba: Enhancing Long-range Dependency for Biomedical Image Segmentationcited by 419
- 2022Learning with Limited Annotations: A Survey on Deep Semi-Supervised Learning for Medical Image Segmentationcited by 76
- 2022Extending nnU-Net is all you needcited by 22
- 2025Federated nnU-Net for Privacy-Preserving Medical Image Segmentationcited by 3
- 2024Quantifying the Impact of Population Shift Across Age and Sex for Abdominal Organ Segmentationcited by 2
- 2022Calibrating Ensembles for Scalable Uncertainty Quantification in Deep Learning-based Medical Segmentationcited by 0
- 2025Federated nnU-Net for Privacy-Preserving Medical Image Segmentation4 Mar 2025
- 2024Quantifying the Impact of Population Shift Across Age and Sex for Abdominal Organ Segmentation8 Aug 2024
- 2024U-Mamba: Enhancing Long-range Dependency for Biomedical Image Segmentation9 Jan 2024
- 2022Calibrating Ensembles for Scalable Uncertainty Quantification in Deep Learning-based Medical Segmentation20 Sep 2022
- 2022Extending nnU-Net is all you need23 Aug 2022
- 2022Learning with Limited Annotations: A Survey on Deep Semi-Supervised Learning for Medical Image Segmentation28 Jul 2022
- 2021The Medical Segmentation Decathlon10 Jun 2021