BaT-SAM: Introducing Inductive Bias into SAM via a Mixture of Convolutional Experts for Brain Tumor Segmentation
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Abstract (arXiv)
Accurate brain tumor segmentation from magnetic resonance imaging (MRI) is essential for diagnosis and treatment planning; however, manual delineation is labor-intensive and time-consuming. Existing approaches are either task-specific with limited generalization or rely on user-provided prompts during inference. We present BaT-SAM, a parameter-efficient adaptation framework that enables fully automatic brain tumor segmentation with the Segment Anything Model (SAM). BaT-SAM injects local inductive bias into SAM's frozen Vision Transformer (ViT) encoder via Conv-LoRA, where image features are processed by a sparsely gated mixture of multi-scale convolutional experts. This design compensates for the limited translation-equivariant inductive bias of vanilla ViTs while fine-tuning fewer than 5M parameters (less than 1% of the full model). To remove the need for user prompts, we further introduce a lightweight self-prompting box regressor that is jointly optimized with the adapter using scheduled sampling and predicts tumor locations directly from image embeddings. On the BRISC2025 benchmark, BaT-SAM achieves a weighted mean IoU of 0.832 while outperforming state-of-the-art benchmarks. It further demonstrates strong cross-dataset generalization, achieving Dice scores of 0.702 on Figshare and 0.784 on the LGG MRI Segmentation dataset.
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References · 20
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,713
- 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,380
- 2023Segment Anythingcited by 8,234
- 2018Encoder-Decoder with Atrous Separable Convolution for Semantic Image Segmentationcited by 3,223
- 2018UNet++: A Nested U-Net Architecture for Medical Image Segmentationcited by 1,525
- 2018Attention U-Net: Learning Where to Look for the Pancreascited by 1,435
- 2018Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challengecited by 511
- 2017LinkNet: Exploiting Encoder Representations for Efficient Semantic Segmentationcited by 214
- 2018Pyramid Attention Network for Semantic Segmentationcited by 149
- 2023SAM-Med2Dcited by 124
- 2019Association of genomic subtypes of lower-grade gliomas with shape features automatically extracted by a deep learning algorithmcited by 77
- 2024Convolution Meets LoRA: Parameter Efficient Finetuning for Segment Anything Modelcited by 69
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- 2021Boundary-Aware Segmentation Network for Mobile and Web Applicationscited by 42
- 2021Enhanced U-Net: A Feature Enhancement Network for Polyp Segmentationcited by 34
- 2025BRISC: Annotated Dataset for Brain Tumor Segmentation and Classificationcited by 15
- 2024Segmenting Medical Images: From UNet to Res-UNet and nnUNetcited by 7
- 2022Towards Complex Backgrounds: A Unified Difference-Aware Decoder for Binary Segmentationcited by 6
- 2024Efficient and Accurate Pneumonia Detection Using a Novel Multi-Scale Transformer Approachcited by 6
- 2024Adapting Segment Anything Model (SAM) to Experimental Datasets via Fine-Tuning on GAN-based Simulation: A Case Study in Additive Manufacturingcited by 5
- 2026XCT-SAM: Sequential Parameter-Efficient Domain Adaptation of SAM for Industrial XCT Defect Segmentationcited by 2
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- 2026A Unified Benchmark of Deep Learning Models for Multi-task 3D Brain Tumor Segmentation from Magnetic Resonance Imaging
- 2024An Ensemble Approach for Brain Tumor Segmentation and Synthesis
- 2025VGDM: Vision-Guided Diffusion Model for Brain Tumor Detection and Segmentation
- 2026an interpretable vision transformer framework for automated brain tumor classification
- 2026Mtextsuperscript4Fuse: Lightweight State-Space MoE with a Cross-Scale Gating Bridge for Brain Tumor Segmentation
- 2026Parameter-Efficient Fine-Tuning of Foundation Models for Liver Tumor Segmentation in CT
- 2025CLISC: Bridging clip and sam by enhanced cam for unsupervised brain tumor segmentation
- 2025NNDM: NN_UNet Diffusion Model for Brain Tumor Segmentation