Sparse cubical complexes for efficient topology-preservation in image data
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Abstract (arXiv)
Persistent homology (PH) is a frequently used tool for extracting and preserving topological information from image data, particularly in image segmentation, where preservation of topological structures is important. However, despite its general applicability across dimensionality, domains, and target structures, the runtime cost of PH-based methods often makes their practical use infeasible. In this work, we argue that this runtime cost is largely driven by processing information that is unimportant for downstream application (e.g. as optimization objective). We propose sparse cubical filtrations as an alternative foundation for PH computation, reducing subsequent computational costs by factors of up to 100 on real datasets. We show close agreement with the optimization signal of the dense counterpart and empirically evaluate our solution's effectiveness as an optimization objective in realistic training regimes where other PH-based objectives can practically not operate (i.e., 3D data with large patch sizes). We show how our solution improves topological accuracy by up to 80% across six diverse datasets while maintaining pixel- and region-based accuracy.
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References · 33
- 2020clDice -- A Novel Topology-Preserving Loss Function for Tubular Structure Segmentationcited by 294
- 2024nnU-Net Revisited: A Call for Rigorous Validation in 3D Medical Image Segmentationcited by 240
- 2019Topology-Preserving Deep Image Segmentationcited by 198
- 2019A Topological Loss Function for Deep-Learning based Image Segmentation using Persistent Homologycited by 134
- 2019Topological Autoencoderscited by 127
- 2019Ripser: efficient computation of Vietoris-Rips persistence barcodescited by 117
- 2017Deep Learning with Topological Signaturescited by 114
- 2023Dynamic Snake Convolution based on Topological Geometric Constraints for Tubular Structure Segmentationcited by 84
- 2018Deep learning to achieve clinically applicable segmentation of head and neck anatomy for radiotherapycited by 77
- 2021Topology-Aware Segmentation Using Discrete Morse Theorycited by 75
- 2022Topologically faithful image segmentation via induced matching of persistence barcodescited by 49
- 2024Skeleton Recall Loss for Connectivity Conserving and Resource Efficient Segmentation of Thin Tubular Structurescited by 43
21 more
- 2019Explicit topological priors for deep-learning based image segmentation using persistent homologycited by 30
- 2018Fast and Accurate Tumor Segmentation of Histology Images using Persistent Homology and Deep Convolutional Featurescited by 28
- 2021Structure-Aware Image Segmentation with Homotopy Warpingcited by 24
- 2020Cubical Ripser: Software for computing persistent homology of image and volume datacited by 23
- 2021A persistent homology-based topological loss for CNN-based multi-class segmentation of CMRcited by 21
- 2025Analysis of the MICCAI Brain Tumor Segmentation -- Metastases (BraTS-METS) 2025 Lighthouse Challenge: Brain Metastasis Segmentation on Pre- and Post-treatment MRIcited by 18
- 2023A skeletonization algorithm for gradient-based optimizationcited by 17
- 2024Topograph: An efficient Graph-Based Framework for Strictly Topology Preserving Image Segmentationcited by 17
- 2022Topological Optimization with Big Stepscited by 16
- 2024TopoCellGen: Generating Histopathology Cell Topology with a Diffusion Modelcited by 16
- 2024Topologically Faithful Multi-class Segmentation in Medical Imagescited by 12
- 2021Persistent Homology with Improved Locality Information for more Effective Delineationcited by 10
- 2024TopoDiffusionNet: A Topology-aware Diffusion Modelcited by 10
- 2024Efficient Betti Matching Enables Topology-Aware 3D Segmentation via Persistent Homologycited by 8
- 2024Topology-Preserving Image Segmentation with Spatial-Aware Persistent Feature Matchingcited by 8
- 2024Pitfalls of topology-aware image segmentationcited by 6
- 2025Topology Optimization in Medical Image Segmentation with Fast Euler Characteristiccited by 5
- 2017Streaming Algorithm for Euler Characteristic Curves of Multidimensional Imagescited by 4
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- 2026Towards High-Quality Image Segmentation: Improving Topology Accuracy by Penalizing Neighbor Pixelscited by 1
- 2026Fast Cubical Persistent Homology on 2D and 3D Images via Union-Find, Pruning, and Lookup Tablescited by 1
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