Structure-Aware Image Segmentation with Homotopy Warping
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Abstract (arXiv)
Besides per-pixel accuracy, topological correctness is also crucial for the segmentation of images with fine-scale structures, e.g., satellite images and biomedical images. In this paper, by leveraging the theory of digital topology, we identify pixels in an image that are critical for topology. By focusing on these critical pixels, we propose a new homotopy warping loss to train deep image segmentation networks for better topological accuracy. To efficiently identify these topologically critical pixels, we propose a new algorithm exploiting the distance transform. The proposed algorithm, as well as the loss function, naturally generalize to different topological structures in both 2D and 3D settings. The proposed loss function helps deep nets achieve better performance in terms of topology-aware metrics, outperforming state-of-the-art structure/topology-aware segmentation methods.
Key facts. Cited by 24 papers in the map (data through 14 Oct 2026). Builds on 24 of its 80 references that are in the map. First posted on arXiv 15 Dec 2021.
Builds on
24 of 80 references.
References · 24
- 2015Deep Residual Learning for Image Recognitioncited by 52,096
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- 2017Mask R-CNNcited by 7,277
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12 more
- 2020clDice -- A Novel Topology-Preserving Loss Function for Tubular Structure Segmentationcited by 294
- 2018DeepGlobe 2018: A Challenge to Parse the Earth through Satellite Imagescited by 277
- 2019Topology-Preserving Deep Image Segmentationcited by 198
- 2018Boundary loss for highly unbalanced segmentationcited by 190
- 2019A Topological Loss Function for Deep-Learning based Image Segmentation using Persistent Homologycited by 134
- 2019Reducing the Hausdorff Distance in Medical Image Segmentation with Convolutional Neural Networkscited by 116
- 2019Boundary-Aware Feature Propagation for Scene Segmentationcited by 107
- 2018RoadTracer: Automatic Extraction of Road Networks from Aerial Imagescited by 102
- 2017Beyond the Pixel-Wise Loss for Topology-Aware Delineationcited by 83
- 2021Topology-Aware Segmentation Using Discrete Morse Theorycited by 75
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- 2017Large Scale Image Segmentation with Structured Loss based Deep Learning for Connectome Reconstructioncited by 5
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Citing papers per year: 2022: 2; 2023: 4; 2024: 7; 2025: 6; 2026: 5.
24 papers.
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- 2023Topology-Aware Uncertainty for Image Segmentationcited by 32
- 2022Learning Topological Interactions for Multi-Class Medical Image Segmentationcited by 28
- 2022Learning Probabilistic Topological Representations Using Discrete Morse Theorycited by 20
- 2024TopoCellGen: Generating Histopathology Cell Topology with a Diffusion Modelcited by 16
- 2023Enhancing Modality-Agnostic Representations via Meta-Learning for Brain Tumor Segmentationcited by 14
- 2023Semi-supervised Segmentation of Histopathology Images with Noise-Aware Topological Consistencycited by 11
- 2024Enhancing Boundary Segmentation for Topological Accuracy with Skeleton-based Methodscited by 9
- 2024Efficient Betti Matching Enables Topology-Aware 3D Segmentation via Persistent Homologycited by 8
- 2024Spatial Diffusion for Cell Layout Generationcited by 5
- 2025Topology Optimization in Medical Image Segmentation with Fast Euler Characteristiccited by 5
- 2023GDDS: Pulmonary Bronchioles Segmentation with Group Deep Dense Supervisioncited by 3
- 2024Universal Topology Refinement for Medical Image Segmentation with Polynomial Feature Synthesiscited by 3
12 more
- 2025Efficient Connectivity-Preserving Instance Segmentation with Supervoxel-Based Loss Functioncited by 3
- 2025MATCH: Multi-faceted Adaptive Topo-Consistency for Semi-Supervised Histopathology Segmentationcited by 3
- 2024Topology-Preserving Downsampling of Binary Imagescited by 2
- 2026Topology-Guaranteed Image Segmentation: Enforcing Connectivity, Genus, and Width Constraintscited by 2
- 2025TopoMortar: A dataset to evaluate image segmentation methods focused on topology accuracycited by 1
- 2025Disconnect to Connect: A Data Augmentation Method for Improving Topology Accuracy in Image Segmentationcited by 1
- 2026Topo-R1: Detecting Topological Anomalies via Vision-Language Modelscited by 1
- 2026Towards High-Quality Image Segmentation: Improving Topology Accuracy by Penalizing Neighbor Pixelscited by 1
- 2024Conformable Convolution for Topologically Aware Learning of Complex Anatomical Structurescited by 0
- 2025ContextLoss: Context Information for Topology-Preserving Segmentationcited by 0
- 2026SAMSEM -- A Generic and Scalable Approach for IC Metal Line Segmentationcited by 0
- 2026Sparse cubical complexes for efficient topology-preservation in image datacited by 0
- 2026Sparse cubical complexes for efficient topology-preservation in image data29 Sep 2026
- 2026Towards High-Quality Image Segmentation: Improving Topology Accuracy by Penalizing Neighbor Pixels19 Mar 2026
- 2026SAMSEM -- A Generic and Scalable Approach for IC Metal Line Segmentation17 Mar 2026
- 2026Topo-R1: Detecting Topological Anomalies via Vision-Language Models13 Mar 2026
- 2026Topology-Guaranteed Image Segmentation: Enforcing Connectivity, Genus, and Width Constraints16 Jan 2026
- 2025MATCH: Multi-faceted Adaptive Topo-Consistency for Semi-Supervised Histopathology Segmentation2 Oct 2025
- 2025Topology Optimization in Medical Image Segmentation with Fast Euler Characteristic31 Jul 2025
- 2025ContextLoss: Context Information for Topology-Preserving Segmentation10 Jun 2025
- 2025Disconnect to Connect: A Data Augmentation Method for Improving Topology Accuracy in Image Segmentation7 Mar 2025
- 2025TopoMortar: A dataset to evaluate image segmentation methods focused on topology accuracy5 Mar 2025
- 2025Efficient Connectivity-Preserving Instance Segmentation with Supervoxel-Based Loss Function2 Jan 2025
- 2024Conformable Convolution for Topologically Aware Learning of Complex Anatomical Structures29 Dec 2024
12 more
- 2024TopoCellGen: Generating Histopathology Cell Topology with a Diffusion Model8 Dec 2024
- 2024Universal Topology Refinement for Medical Image Segmentation with Polynomial Feature Synthesis15 Sep 2024
- 2024Spatial Diffusion for Cell Layout Generation4 Sep 2024
- 2024Topology-Preserving Downsampling of Binary Images25 Jul 2024
- 2024Efficient Betti Matching Enables Topology-Aware 3D Segmentation via Persistent Homology5 Jul 2024
- 2024Enhancing Boundary Segmentation for Topological Accuracy with Skeleton-based Methods29 Apr 2024
- 2023Semi-supervised Segmentation of Histopathology Images with Noise-Aware Topological Consistency28 Nov 2023
- 2023Topology-Aware Uncertainty for Image Segmentation9 Jun 2023
- 2023GDDS: Pulmonary Bronchioles Segmentation with Group Deep Dense Supervision16 Mar 2023
- 2023Enhancing Modality-Agnostic Representations via Meta-Learning for Brain Tumor Segmentation8 Feb 2023
- 2022Learning Topological Interactions for Multi-Class Medical Image Segmentation20 Jul 2022
- 2022Learning Probabilistic Topological Representations Using Discrete Morse Theory3 Jun 2022
- 2023Topology-Aware Uncertainty for Image Segmentationcited by 32
- 2022Learning Topological Interactions for Multi-Class Medical Image Segmentationcited by 28
- 2022Learning Probabilistic Topological Representations Using Discrete Morse Theorycited by 20
- 2023Enhancing Modality-Agnostic Representations via Meta-Learning for Brain Tumor Segmentationcited by 14
- 2023Semi-supervised Segmentation of Histopathology Images with Noise-Aware Topological Consistencycited by 11
- 2024Enhancing Boundary Segmentation for Topological Accuracy with Skeleton-based Methodscited by 9
- 2024Efficient Betti Matching Enables Topology-Aware 3D Segmentation via Persistent Homologycited by 8
- 2025Topology Optimization in Medical Image Segmentation with Fast Euler Characteristiccited by 5
- 2023GDDS: Pulmonary Bronchioles Segmentation with Group Deep Dense Supervisioncited by 3
- 2024Universal Topology Refinement for Medical Image Segmentation with Polynomial Feature Synthesiscited by 3
- 2025Efficient Connectivity-Preserving Instance Segmentation with Supervoxel-Based Loss Functioncited by 3
- 2025MATCH: Multi-faceted Adaptive Topo-Consistency for Semi-Supervised Histopathology Segmentationcited by 3
12 most cited of 21 All 21 (JSON)
- 2026Sparse cubical complexes for efficient topology-preservation in image data29 Sep 2026
- 2026Towards High-Quality Image Segmentation: Improving Topology Accuracy by Penalizing Neighbor Pixels19 Mar 2026
- 2026SAMSEM -- A Generic and Scalable Approach for IC Metal Line Segmentation17 Mar 2026
- 2026Topology-Guaranteed Image Segmentation: Enforcing Connectivity, Genus, and Width Constraints16 Jan 2026
- 2025MATCH: Multi-faceted Adaptive Topo-Consistency for Semi-Supervised Histopathology Segmentation2 Oct 2025
- 2025Topology Optimization in Medical Image Segmentation with Fast Euler Characteristic31 Jul 2025
- 2025ContextLoss: Context Information for Topology-Preserving Segmentation10 Jun 2025
- 2025Disconnect to Connect: A Data Augmentation Method for Improving Topology Accuracy in Image Segmentation7 Mar 2025
- 2025TopoMortar: A dataset to evaluate image segmentation methods focused on topology accuracy5 Mar 2025
- 2025Efficient Connectivity-Preserving Instance Segmentation with Supervoxel-Based Loss Function2 Jan 2025
- 2024Conformable Convolution for Topologically Aware Learning of Complex Anatomical Structures29 Dec 2024
- 2024Universal Topology Refinement for Medical Image Segmentation with Polynomial Feature Synthesis15 Sep 2024
12 newest of 21 All 21 (JSON)