mlsanityData to 7 Oct 2026

Rethinking Diffusion Segmentation: When Does It Rely on Its Noisy State, and Does Diffusion Matter?

arXiv 2609.23967 ↗First posted 21 Sep 2026cs.CV cs.LGcited by 0

On the map: Diffusion models → Diffusion foundations and sampling

Abstract (arXiv)

Diffusion models are increasingly adapted from generation to conditional prediction, where a conditioning signal is combined with an evolving noisy representation of the target. In fully supervised segmentation, however, the conditioning image can already support direct target prediction, so endpoint performance alone establishes neither reliance on the added diffusion state nor a deterministic advantage over image-only prediction. For state reliance, we disrupt target-derived state content or correct image-state pairing during retraining of twelve published methods across three datasets, with ten matched seeds per setting. All 40 original-method comparisons whose evaluated-mask routes remained downstream of noised-quantity reconstruction exhibited state reliance, whereas all 30 comparisons with a segmentation-supervised bypass preserved reference performance. Rerouting five originally bypass-capable methods by forcing segmentation supervision through noise-to-mask reconstruction converted all 30 corresponding comparisons from preserved performance to state reliance. For deterministic utility, matched image-only counterparts achieved similar or better performance in 28 of 35 settings overall, including 16 of 20 whose native methods relied on both audited state properties. These results identify supervision path as a determinant of state reliance in the audited methods. Separately, matched image-only counterparts show that diffusion-specific computation often provides no deterministic endpoint advantage, including in methods that rely on the audited state properties. More generally, when conditioning already supports strong target prediction, diffusion-specific claims require additional evidence that the added state is used and that diffusion-specific computation improves the claimed capability beyond a matched condition-only counterpart.

Key facts. No citing papers in the map yet (data through 7 Oct 2026). Placed in Diffusion foundations and sampling, one of 14 directions in Diffusion models. Builds on 18 of its 35 references that are in the map. First posted on arXiv 21 Sep 2026.

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18 of 35 references.

Closest ancestors · 1

Same direction, newest first

  1. 2020Denoising Diffusion Probabilistic Models19 Jun

Other references · 17

  1. 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
  2. 2019Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)cited by 657
  3. 2021SegDiff: Image Segmentation with Diffusion Probabilistic Modelscited by 279
  4. 2021Diffusion Models for Implicit Image Segmentation Ensemblescited by 198
  5. 2022MedSegDiff: Medical Image Segmentation with Diffusion Probabilistic Modelcited by 180
  6. 2023MedSegDiff-V2: Diffusion based Medical Image Segmentation with Transformercited by 124
  7. 2023Ambiguous Medical Image Segmentation using Diffusion Modelscited by 92
  8. 2023BerDiff: Conditional Bernoulli Diffusion Model for Medical Image Segmentationcited by 27
  9. 2024Stable Diffusion Segmentation for Biomedical Images with Single-step Reverse Processcited by 16
  10. 2023Annotator Consensus Prediction for Medical Image Segmentation with Diffusion Modelscited by 10
  11. 2023Importance of Aligning Training Strategy with Evaluation for Diffusion Models in 3D Multiclass Segmentationcited by 5
  12. 2023A Recycling Training Strategy for Medical Image Segmentation with Diffusion Denoising Modelscited by 5
5 more
  1. 2024Latent Diffusion for Medical Image Segmentation: End to end learning for fast sampling and accuracycited by 5
  2. 2025Conditional diffusion model with spatial attention and latent embedding for medical image segmentationcited by 5
  3. 2025Ambiguous Medical Image Segmentation Using Diffusion Schr"odinger Bridgecited by 5
  4. 2025UniSegDiff: Boosting Unified Lesion Segmentation via a Staged Diffusion Modelcited by 2
  5. 2025LEAF: Latent Diffusion with Efficient Encoder Distillation for Aligned Features in Medical Image Segmentationcited by 1

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  1. 2024Analysing Diffusion Segmentation for Medical Images
  2. 2023Denoising Diffusion Semantic Segmentation with Mask Prior Modeling
  3. 2024Tracing the Roots: Leveraging Temporal Dynamics in Diffusion Trajectories for Origin Attribution
  4. 2026A Plug-in Interpretation of Conditioning in Score-Based Diffusion Models
  5. 2024Diffusion Models Need Visual Priors for Image Generation
  6. 2025Temporal Score Analysis for Understanding and Correcting Diffusion Artifacts
  7. 2023Faster Diffusion: Rethinking the Role of the Encoder for Diffusion Model Inference
  8. 2024Hybrid diffusion models: combining supervised and generative pretraining for label-efficient fine-tuning of segmentation models