ChemWorld: Programmable Chemical Worlds for Controlled and Replayable Agent Experimentation
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Abstract (arXiv)
Autonomous chemistry increasingly depends on environments in which agents can repeatedly act, observe, and adapt.Physical laboratories provide essential real-material evidence but are costly to repeat and difficult to use for tightly matched interventions, whereas most digital environments keep the underlying experimental world largely fixed. We introduce ChemWorld, a programmable chemical environment in which reusable process and observation components are compiled into executable worlds. ChemWorld separates the public experimental contract available to an agent from evaluator-owned chemical and material laws. Researchers can therefore vary world composition and operating conditions, or change a single hidden law while holding the public task and interaction conditions fixed. Transactional execution records operations, failures, resource changes, and state transitions, allowing complete environment-action trajectories to be replayed exactly and audited. Full-census qualification covered the reference registry, 52 generated compositions, and module, interface, compilation, and invalid-action tests. Eight deterministic experimental cases demonstrated shared lifecycle semantics, failure recovery, and exact replay, while six parent-child world-fork pairs isolated the effects of single private-law interventions under matched public conditions. An independent agent also completed a full lifecycle in a non-reference world through the same public interface. Within the declared component and model domain, ChemWorld provides a controlled and replayable substrate for studying experimentation across systematically varied chemical worlds, complementary to physical-laboratory evidence and calibration.
Key facts. No citing papers in the map yet (data through 7 Oct 2026). Builds on 14 of its 22 references that are in the map. First posted on arXiv 11 Aug 2026.
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References · 14
- 2023ChemCrow: Augmenting large-language models with chemistry toolscited by 609
- 2024DISCOVERYWORLD: A Virtual Environment for Developing and Evaluating Automated Scientific Discovery Agentscited by 89
- 2024ORGANA: A Robotic Assistant for Automated Chemistry Experimentation and Characterizationcited by 60
- 2025NewtonBench: Benchmarking Generalizable Scientific Law Discovery in LLM Agentscited by 32
- 2020Olympus: a benchmarking framework for noisy optimization and experiment planningcited by 28
- 2025BoxingGym: Benchmarking Progress in Automated Experimental Design and Model Discoverycited by 15
- 2025LabUtopia: High-Fidelity Simulation and Hierarchical Benchmark for Scientific Embodied Agentscited by 14
- 2025AutoLabs: Cognitive Multi-Agent Systems with Self-Correction for Autonomous Chemical Experimentationcited by 13
- 2025Measuring Scientific Capabilities of Language Models with a Systems Biology Dry Labcited by 11
- 2024PC-Gym: Benchmark Environments For Process Control Problemscited by 8
- 2025Agentic Exploration of Physics Modelscited by 5
- 2026MADE: Benchmark Environments for Closed-Loop Materials Discoverycited by 5
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