MedCalc-R1: Knowledge-Guided Reward Framework for Medical Mathematical Reasoning
On the map: LLM reasoning → Clinical and biomedical applications
Abstract (arXiv)
In Reinforcement Learning with Verifiable Rewards (RLVR) frameworks for mathematical reasoning tasks, floating-point results are typically evaluated using a tolerance-based reward. However, this strategy suffers from challenges such as difficulty in threshold calibration, unstable training dynamics, and limited accuracy, especially in clinical scenarios. To address these limitations, we propose a knowledge-guided hybrid reward framework (textscMedCalc-R1). Specifically, we introduce a knowledge verification reward mechanism that enforces explicit generation of computational formulas, which are further validated by an external verifier to enhance interpretability and reasoning reliability. Furthermore, we design a hybrid soft-hard reward scheme combining a hard constraint based on clinical safety thresholds with a soft, precision-sensitive reward that progressively guides learning within the acceptable range. Experimental results demonstrate that our method significantly outperforms existing baselines in both reasoning accuracy and generalization capability, validating the effectiveness and applicability in safety-critical domains.
Key facts. Cited by 1 paper in the map (data through 14 Oct 2026). Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning. Builds on 19 of its 47 references that are in the map. First posted on arXiv 9 Aug 2026.
Builds on
19 of 47 references.
Closest ancestors · 2
Same direction, newest first
- 2025Med-R1: Reinforcement Learning for Generalizable Medical Reasoning in Vision-Language Models18 Mar
- 2024HuatuoGPT-o1, Towards Medical Complex Reasoning with LLMs25 Dec
Other references · 17
- 2017Proximal Policy Optimization Algorithmscited by 15,215
- 2021Training Verifiers to Solve Math Word Problemscited by 10,109
- 2024DeepSeekMath: Pushing the Limits of Mathematical Reasoning in Open Language Modelscited by 9,379
- 2025DeepSeek-R1: Incentivizing Reasoning Capability in LLMs via Reinforcement Learningcited by 6,330
- 2024Qwen2.5 Technical Reportcited by 4,942
- 2024GPT-4o System Cardcited by 4,588
- 2021Program Synthesis with Large Language Modelscited by 3,637
- 2024OpenAI o1 System Cardcited by 1,244
- 2024DeepSeek-Coder: When the Large Language Model Meets Programming -- The Rise of Code Intelligencecited by 1,181
- 2024Qwen2.5-Math Technical Report: Toward Mathematical Expert Model via Self-Improvementcited by 1,090
- 2025Towards Large Reasoning Models: A Survey of Reinforced Reasoning with Large Language Modelscited by 293
- 2025REINFORCE++: Stabilizing Critic-Free Policy Optimization with Global Advantage Normalizationcited by 241
5 more
- 2025Crossing the Reward Bridge: Expanding RL with Verifiable Rewards Across Diverse Domainscited by 156
- 2024Reinforcement Learning Enhanced LLMs: A Surveycited by 71
- 2025Logical Reasoning in Large Language Models: A Surveycited by 55
- 2025A Survey on Large Language Models for Mathematical Reasoningcited by 52
- 2024Relevant or Random: Can LLMs Truly Perform Analogical Reasoning?cited by 8
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Citing papers per year: 2026: 1.
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Similar, not cited
Close in wording, no citation either way
- 2025Med-RLVR: Emerging Medical Reasoning from a 3B base model via reinforcement Learning
- 2026Scaling Medical Reasoning Verification via Tool-Integrated Reinforcement Learning
- 2025Improving Medical Reasoning with Curriculum-Aware Reinforcement Learning
- 2025Reward Hacking Mitigation using Verifiable Composite Rewards
- 2025The Good, The Bad, and The Hybrid: A Reward Structure Showdown in Reasoning Models Training
- 2025Med-R3: Enhancing Medical Retrieval-Augmented Reasoning of LLMs via Progressive Reinforcement Learning
- 2025Adaptive Reinforcement for Open-ended Medical Reasoning via Semantic-Guided Reward Collapse Mitigation
- 2025Fleming-R1: Toward Expert-Level Medical Reasoning via Reinforcement Learning