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Spatiotemporal Proximal Causal Inference under Hidden Confounding and Interference

arXiv 2608.01352 ↗First posted 2 Aug 2026cs.LG cs.AIcited by 0

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Abstract (arXiv)

Estimating causal effects from real-world spatiotemporal data is challenging due to hidden confounders and interference. Standard causal identification methods assume conditional exchangeability given observed covariates, which fails whenever hidden confounders affect both treatment and outcomes - a common setting in domains such as climate, environmental policy, epidemiology, and regional economics. In this paper, we propose a novel spatiotemporal proximal causal inference framework that extends proximal identification theory to spatiotemporal settings. The proposed method jointly captures local and neighborhood-level confounding information by introducing treatment- and outcome-inducing proxies, and we derive a spatiotemporal outcome confounding bridge function that identifies the potential outcome without requiring direct recovery of the hidden confounder. We establish the identifiability of this bridge function under proxy exclusion restrictions and a spatiotemporal completeness condition, and show that the resulting estimator recovers the outcome through a proximal generalization of the g-computation formula. To operationalize this identification result, we propose a neural architecture that learns proxies via transformer-based spatiotemporal encoders - coupled with a conditional mutual information critic to enforce exclusion restrictions and a moment-matching network to guarantee that the learned bridge function satisfies the underlying identifying equation. We further introduce a stabilized weighting scheme to address treatment support imbalance. Experiments on synthetic datasets demonstrate that our approach achieves comparable performance to baseline causal inference methods, while providing, to our knowledge, the first theoretically grounded outcomes for the hidden confounding in the presence of spatiotemporal interference through a proximal causal inference framework.

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References · 18

  1. 2020CLUB: A Contrastive Log-ratio Upper Bound of Mutual Informationcited by 233
  2. 2016Identifying Causal Effects With Proxy Variables of an Unmeasured Confoundercited by 138
  3. 2019Deep Generalized Method of Moments for Instrumental Variable Analysiscited by 88
  4. 2020Minimax Estimation of Conditional Moment Modelscited by 83
  5. 2019Time Series Deconfounder: Estimating Treatment Effects over Time in the Presence of Hidden Confounderscited by 74
  6. 2021Proximal Causal Learning with Kernels: Two-Stage Estimation and Moment Restrictioncited by 54
  7. 2016Identification and estimation of treatment and interference effects in observational studies on networkscited by 43
  8. 2018A confounding bridge approach for double negative control inference on causal effectscited by 36
  9. 2020Kernel Methods for Unobserved Confounding: Negative Controls, Proxies, and Instrumentscited by 27
  10. 2019On Multi-Cause Causal Inference with Unobserved Confounding: Counterexamples, Impossibility, and Alternativescited by 20
  11. 2019Comment on "Blessings of Multiple Causes"cited by 16
  12. 2021Theory for identification and Inference with Synthetic Controls: A Proximal Causal Inference Frameworkcited by 9
6 more
  1. 2023Spatial causal inference in the presence of unmeasured confounding and interferencecited by 9
  2. 2020Generalized propensity score approach to causal inference with spatial interferencecited by 7
  3. 2025GST-UNet: A Neural Framework for Spatiotemporal Causal Inference with Time-Varying Confoundingcited by 5
  4. 2020Spatial+: a novel approach to spatial confoundingcited by 4
  5. 2025Spatial Deconfounder: Interference-Aware Deconfounding for Spatial Causal Inferencecited by 3
  6. 2024An Instrumental Variables Framework to Unite Spatial Confounding Methodscited by 2

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