LiteMedCoT-VL: Parameter-Efficient Adaptation for Medical Visual Question Answering
On the map: Multimodal LLMs / vision-language models → Medical vision-language models
Abstract (arXiv)
The reasoning gap between large and compact vision-language models (VLMs) limits the deployment of medical AI on portable clinical devices. Compact VLMs of 2-4B parameters can run on resource-constrained hardware but lack the multi-step reasoning capacity needed for interpretable clinical decision support. Existing knowledge distillation methods transfer answers without the reasoning process behind them. Medical visual question answering (VQA) serves as a testbed for this problem, as it requires models to integrate visual evidence with clinical knowledge through structured reasoning chains. We introduce LiteMedCoT-VL, a pipeline that transfers chain-of-thought reasoning from a 235B teacher model to 2B student models through LoRA-based fine-tuning on explanation-enriched training data. All inference is conducted without image captions by default, simulating the clinical scenario in which a physician interprets a medical image directly without an accompanying radiology report. On the PMC-VQA benchmark, LiteMedCoT-VL achieves 64.9% accuracy, exceeding the zero-shot Qwen3-VL-4B baseline of 53.9% by 11.0 percentage points and outperforming all published baselines. This result indicates that a 2B model with reasoning distillation can match or exceed models with twice the parameters. Visual grounding analysis shows that the model relies on image content rather than exploiting textual priors. Our code is publicly available at https://github.com/R4nzer/LiteMedCoT-VL.
Key facts. No citing papers in the map yet (data through 7 Oct 2026). Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 43 of its 58 references that are in the map. First posted on arXiv 10 May 2026.
Builds on
43 of 58 references.
Closest ancestors · 6
Same direction, newest first
- 2026CheXthought: A global multimodal dataset of clinical chain-of-thought reasoning and visual attention for chest X-ray interpretation29 Apr
- 2026MedVR: Annotation-Free Medical Visual Reasoning via Agentic Reinforcement Learning9 Apr
- 2026CARE: Towards Clinical Accountability in Multi-Modal Medical Reasoning with an Evidence-Grounded Agentic Framework2 Mar
- 2025The Impact of Image Resolution on Biomedical Multimodal Large Language Models21 Oct
- 2025Think Twice to See More: Iterative Visual Reasoning in Medical VLMs11 Oct
- 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day1 Jun
Other references · 37
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- 2021TransUNet: Transformers Make Strong Encoders for Medical Image Segmentationcited by 1,552
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25 more
- 2024How Far Are We to GPT-4V? Closing the Gap to Commercial Multimodal Models with Open-Source Suitescited by 1,033
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- 2020PathVQA: 30000+ Questions for Medical Visual Question Answeringcited by 467
- 2021SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answeringcited by 444
- 2023PMC-VQA: Visual Instruction Tuning for Medical Visual Question Answeringcited by 333
- 2022Large Language Models Are Reasoning Teacherscited by 318
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- 2024Hallucination Benchmark in Medical Visual Question Answeringcited by 18
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- 2026Beyond Accuracy: Evaluating Visual Grounding In Multimodal Medical Reasoningcited by 6
- 2026Step-CoT: Stepwise Visual Chain-of-Thought for Medical Visual Question Answeringcited by 2
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- 2025MedCLM: Learning to Localize and Reason via a CoT-Curriculum in Medical Vision-Language Models
- 2024Fusion of Domain-Adapted Vision and Language Models for Medical Visual Question Answering
- 2025AMANDA: Agentic Medical Knowledge Augmentation for Data-Efficient Medical Visual Question Answering
- 2025GEMeX-RMCoT: An Enhanced Med-VQA Dataset for Region-Aware Multimodal Chain-of-Thought Reasoning
- 2026MedProb: Probing Internal Representations of Vision-Language Models for Medical Question Answering
- 2023Visual Question Answering in the Medical Domain