LLMdoctor: Token-Level Flow-Guided Preference Optimization for Efficient Test-Time Alignment of Large Language Models
On the map: LLM alignment / RLHF / preference optimisation → Medical LLM alignment
Abstract (arXiv)
Aligning Large Language Models (LLMs) with human preferences is critical, yet traditional fine-tuning methods are computationally expensive and inflexible. While test-time alignment offers a promising alternative, existing approaches often rely on distorted trajectory-level signals or inefficient sampling, fundamentally capping performance and failing to preserve the generative diversity of the base model. This paper introduces LLMdoctor, a novel framework for efficient test-time alignment that operates via a patient-doctor paradigm. It integrates token-level reward acquisition with token-level flow-guided preference optimization (TFPO) to steer a large, frozen patient LLM with a smaller, specialized doctor model. Unlike conventional methods that rely on trajectory-level rewards, LLMdoctor first extracts fine-grained, token-level preference signals from the patient model's behavioral variations. These signals then guide the training of the doctor model via TFPO, which establishes flow consistency across all subtrajectories, enabling precise token-by-token alignment while inherently preserving generation diversity. Extensive experiments demonstrate that LLMdoctor significantly outperforms existing test-time alignment methods and even surpasses the performance of full fine-tuning approaches like DPO.
Key facts. Cited by 1 paper in the map (data through 7 Oct 2026). Placed in Medical LLM alignment, one of 10 directions in LLM alignment / RLHF / preference optimisation. Builds on 27 of its 39 references that are in the map. First posted on arXiv 15 Jan 2026.
Builds on
27 of 39 references.
References · 27
- 2022Training language models to follow instructions with human feedbackcited by 15,712
- 2023Direct Preference Optimization: Your Language Model is Secretly a Reward Modelcited by 7,916
- 2023UltraFeedback: Boosting Language Models with Scaled AI Feedbackcited by 394
- 2023Rewarded soups: towards Pareto-optimal alignment by interpolating weights fine-tuned on diverse rewardscited by 232
- 2023Helping or Herding? Reward Model Ensembles Mitigate but do not Eliminate Reward Hackingcited by 195
- 2024DPO Meets PPO: Reinforced Token Optimization for RLHFcited by 126
- 2024ARGS: Alignment as Reward-Guided Searchcited by 99
- 2024Reinforcement Learning for LLM Post-Training: A Surveycited by 91
- 2024Decoding-Time Language Model Alignment with Multiple Objectivescited by 90
- 2024PAD: Personalized Alignment of LLMs at Decoding-Timecited by 58
- 2024GenARM: Reward Guided Generation with Autoregressive Reward Model for Test-time Alignmentcited by 54
- 2025Token Cleaning: Fine-Grained Data Selection for LLM Supervised Fine-Tuningcited by 39
15 more
- 2024Cascade Reward Sampling for Efficient Decoding-Time Alignmentcited by 38
- 2024A Comprehensive Survey of Direct Preference Optimization: Datasets, Theories, Variants, and Applicationscited by 27
- 2025PARM: Multi-Objective Test-Time Alignment via Preference-Aware Autoregressive Reward Modelcited by 27
- 2024Selective Preference Optimization via Token-Level Reward Function Estimationcited by 25
- 2025AlignDistil: Token-Level Language Model Alignment as Adaptive Policy Distillationcited by 15
- 2025Self-Consistency of the Internal Reward Models Improves Self-Rewarding Language Modelscited by 13
- 2024Dynamic Rewarding with Prompt Optimization Enables Tuning-free Self-Alignment of Language Modelscited by 12
- 2024SparsePO: Controlling Preference Alignment of LLMs via Sparse Token Maskscited by 9
- 2025Guided Speculative Inference for Efficient Test-Time Alignment of LLMscited by 9
- 2025Collaborative Multi-LoRA Experts with Achievement-based Multi-Tasks Loss for Unified Multimodal Information Extractioncited by 7
- 2024UNA: A Unified Supervised Framework for Efficient LLM Alignment Across Feedback Typescited by 6
- 2024HAF-RM: A Hybrid Alignment Framework for Reward Model Trainingcited by 5
- 2024Elephant in the Room: Unveiling the Impact of Reward Model Quality in Alignmentcited by 4
- 2025Energy-Based Reward Models for Robust Language Model Alignmentcited by 4
- 2025RIDE: Enhancing Large Language Model Alignment through Restyled In-Context Learning Demonstration Exemplarscited by 2
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Citing papers per year: 2026: 1.
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- 2024Inference time LLM alignment in single and multidomain preference spectrum
- 2025Test-Time Preference Optimization: On-the-Fly Alignment via Iterative Textual Feedback
- 2025Not All Preferences are What You Need for Post-Training: Selective Alignment Strategy for Preference Optimization
- 2024Reward-Augmented Data Enhances Direct Preference Alignment of LLMs
- 2026Reliability-Aware LLM Alignment from Inconsistent Human Feedback
- 2025DiffPO: Diffusion-styled Preference Optimization for Efficient Inference-Time Alignment of Large Language Models
- 2025P-Aligner: Enabling Pre-Alignment of Language Models via Principled Instruction Synthesis
- 2024Spread Preference Annotation: Direct Preference Judgment for Efficient LLM Alignment