mlsanityData to 7 Oct 2026

Visual Alignment of Medical Vision-Language Models for Grounded Radiology Report Generation

arXiv 2512.16201 ↗First posted 18 Dec 2025cs.CVcited by 5

On the map: Multimodal LLMs / vision-language models → Medical vision-language models

Abstract (arXiv)

Radiology Report Generation (RRG) is a critical step toward automating healthcare workflows, facilitating accurate patient assessments, and reducing the workload of medical professionals. Despite recent progress in Large Medical Vision-Language Models (Med-VLMs), generating radiology reports that are both visually grounded and clinically accurate remains a significant challenge. Existing approaches often rely on large labeled corpora for pre-training, costly task-specific preference data, or retrieval-based knowledge. However, these strategies do not adequately mitigate hallucinations arising from poor cross-modal alignment between visual and linguistic representations. To address these limitations, we propose VALOR: Visual Alignment of Medical Vision-Language Models for GrOunded Radiology Report Generation, which tackles visual hallucinations through two complementary reasoning stages: (1) Clinically Informed Textual Reasoning guides the model with verifiable natural language and clinical metric rewards to produce semantically complete reports with precise medical terminology. (2) Self-Supervised Visual Reasoning leverages a frozen domain expert to compute image-text similarity scores between the input chest X-ray and generated candidates, converting these into rank-normalized advantages that explicitly steer the policy toward visually grounded outputs, requiring no preference pairs, retrieval databases, or additional annotations. Extensive experiments on multiple benchmarks demonstrate that VALOR substantially improves generation quality, as well as clinical accuracy which are visually grounded, achieving significant performance gains over state-of-the-art medical report generation benchmarks.

Key facts. Cited by 5 papers in the map (data through 7 Oct 2026). Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 58 of its 67 references that are in the map. First posted on arXiv 18 Dec 2025.

Builds on

58 of 67 references.

Closest ancestors · 8

Same direction, newest first

  1. 2024MMedPO: Aligning Medical Vision-Language Models with Clinical-Aware Multimodal Preference Optimization9 Dec
  2. 2024VILA-M3: Enhancing Vision-Language Models with Medical Expert Knowledge19 Nov
  3. 2024MMed-RAG: Versatile Multimodal RAG System for Medical Vision Language Models16 Oct
  4. 2024RULE: Reliable Multimodal RAG for Factuality in Medical Vision Language Models6 Jul
  5. 2024MMedAgent: Learning to Use Medical Tools with Multi-modal Agent2 Jul
  6. 2024HuatuoGPT-Vision, Towards Injecting Medical Visual Knowledge into Multimodal LLMs at Scale27 Jun
  7. 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day1 Jun
  8. 2023BiomedGPT: A Generalist Vision-Language Foundation Model for Diverse Biomedical Tasks26 May

Other references · 50

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38 more
  1. 2020What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Examscited by 1,324
  2. 2023Aligning Large Multimodal Models with Factually Augmented RLHFcited by 703
  3. 2023Mitigating Object Hallucinations in Large Vision-Language Models through Visual Contrastive Decodingcited by 671
  4. 2022MedCLIP: Contrastive Learning from Unpaired Medical Images and Textcited by 564
  5. 2023BiomedCLIP: a multimodal biomedical foundation model pretrained from fifteen million scientific image-text pairscited by 506
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  15. 2022Cross-modal Memory Networks for Radiology Report Generationcited by 183
  16. 2024MAIRA-2: Grounded Radiology Report Generationcited by 140
  17. 2023Interactive and Explainable Region-guided Radiology Report Generationcited by 139
  18. 2024RLAIF-V: Open-Source AI Feedback Leads to Super GPT-4V Trustworthinesscited by 129
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  25. 2024Detecting and Evaluating Medical Hallucinations in Large Vision Language Modelscited by 57
  26. 2024MADTP: Multimodal Alignment-Guided Dynamic Token Pruning for Accelerating Vision-Language Transformercited by 53
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  29. 2024Understand What LLM Needs: Dual Preference Alignment for Retrieval-Augmented Generationcited by 27
  30. 2024Fact-Aware Multimodal Retrieval Augmentation for Accurate Medical Radiology Report Generationcited by 23
  31. 2024Understanding Alignment in Multimodal LLMs: A Comprehensive Studycited by 22
  32. 2024Biomedical Visual Instruction Tuning with Clinician Preference Alignmentcited by 21
  33. 2023SkinGPT-4: An Interactive Dermatology Diagnostic System with Visual Large Language Modelcited by 18
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  38. 2025Instruction-Oriented Preference Alignment for Enhancing Multi-Modal Comprehension Capability of MLLMscited by 1

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2026: 5.

5 papers.

Similar, not cited

Close in wording, no citation either way

  1. 2025RadAlign: Advancing Radiology Report Generation with Vision-Language Concept Alignment
  2. 2024SERPENT-VLM : Self-Refining Radiology Report Generation Using Vision Language Models
  3. 2025Med-R2: Perception and Reflection-driven Complex Reasoning for Medical Report Generation
  4. 2026LEAD: Layer-wise Expert-aligned Decoding for Faithful Radiology Report Generation
  5. 2026RadPRISM: Schema-stratified radiology-report supervision for concept-disentangled image representations and visual grounding
  6. 2026Graph-Supervised Hierarchical Clinical Alignment for Radiology Report Generation with Large Language Models
  7. 2026Learning to See Locally and Align Clinically with Pathology Semantics for Radiology Report Generation
  8. 2026Homogeneous Semantic Alignment and Hierarchical Expert Routing for Radiology Report Generation