mlsanityData to 7 Oct 2026

Aviary: training language agents on challenging scientific tasks

arXiv 2412.21154 ↗First posted 30 Dec 2024cs.AI cs.CL cs.LGcited by 23

On the map: LLM agents and tool use → Web, search, and research agents

Abstract (arXiv)

Solving complex real-world tasks requires cycles of actions and observations. This is particularly true in science, where tasks require many cycles of analysis, tool use, and experimentation. Language agents are promising for automating intellectual tasks in science because they can interact with tools via natural language or code. Yet their flexibility creates conceptual and practical challenges for software implementations, since agents may comprise non-standard components such as internal reasoning, planning, tool usage, as well as the inherent stochasticity of temperature-sampled language models. Here, we introduce Aviary, an extensible gymnasium for language agents. We formalize agents as policies solving language-grounded partially observable Markov decision processes, which we term language decision processes. We then implement five environments, including three challenging scientific environments: (1) manipulating DNA constructs for molecular cloning, (2) answering research questions by accessing scientific literature, and (3) engineering protein stability. These environments were selected for their focus on multi-step reasoning and their relevance to contemporary biology research. Finally, with online training and scaling inference-time compute, we show that language agents backed by open-source, non-frontier LLMs can match and exceed both frontier LLM agents and human experts on multiple tasks at up to 100x lower inference cost.

Key facts. Cited by 23 papers in the map (data through 7 Oct 2026). Placed in Web, search, and research agents, one of 16 directions in LLM agents and tool use. Builds on 51 of its 140 references that are in the map. First posted on arXiv 30 Dec 2024.

Builds on

51 of 140 references.

Closest ancestors · 4

Same direction, newest first

  1. 2024Language agents achieve superhuman synthesis of scientific knowledge10 Sep
  2. 2024DiscoveryBench: Towards Data-Driven Discovery with Large Language Models1 Jul
  3. 2024DS-Agent: Automated Data Science by Empowering Large Language Models with Case-Based Reasoning27 Feb
  4. 2023PaperQA: Retrieval-Augmented Generative Agent for Scientific Research8 Dec

Other references · 47

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  12. 2023Large Language Models Empowered Agent-based Modeling and Simulation: A Survey and Perspectivescited by 253
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  22. 2023Pangu-Agent: A Fine-Tunable Generalist Agent with Structured Reasoningcited by 30
  23. 2024DynaSaur: Large Language Agents Beyond Predefined Actionscited by 30
  24. 2024Enhancing Decision-Making for LLM Agents via Step-Level Q-Value Modelscited by 28
  25. 2023DSPy Assertions: Computational Constraints for Self-Refining Language Model Pipelinescited by 27
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  28. 2024Tapilot-Crossing: Benchmarking and Evolving LLMs Towards Interactive Data Analysis Agentscited by 17
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Citing papers per year: 2025: 15; 2026: 8.

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  2. 2025Training a Scientific Reasoning Model for Chemistrycited by 54
  3. 2025EXP-Bench: Can AI Conduct AI Research Experiments?cited by 36
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  10. 2025Advancing the Scientific Method with Large Language Models: From Hypothesis to Discoverycited by 7
  11. 2025CAPO: Cost-Aware Prompt Optimizationcited by 6
  12. 2025URSA: The Universal Research and Scientific Agentcited by 6
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  2. 2026LABBench2: An Improved Benchmark for AI Systems Performing Biology Researchcited by 6
  3. 2025CFDLLMBench: A Benchmark Suite for Evaluating Large Language Models in Computational Fluid Dynamicscited by 5
  4. 2026AgenticRed: Evolving Agentic Systems for Red-Teamingcited by 4
  5. 2025A Large-Scale Vision-Language Dataset Derived from Open Scientific Literature to Advance Biomedical Generalist AIcited by 2
  6. 2025An Auditable Agent Platform For Automated Molecular Optimisationcited by 2
  7. 2026Bifrost: Steering Strategic Trajectories to Bridge Contextual Gaps for Self-Improving Agentscited by 2
  8. 2026ScienceIDE: Turning World's Scientific Codebase into Agent Learnable Environmentscited by 2
  9. 2026STEMVerse: A Dual-Axis Diagnostic Framework for STEM Reasoning in Large Language Modelscited by 1
  10. 2026Clever Materials: When Models Identify Good Materials for the Wrong Reasonscited by 1
  11. 2026Self-Driving Datasets: From 20 Million Papers to Nuanced Biomedical Knowledge at Scalecited by 0

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