Still Not Quite There! Evaluating Large Language Models for Comorbid Mental Health Diagnosis
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Abstract (arXiv)
In this study, we introduce ANGST, a novel, first-of-its kind benchmark for depression-anxiety comorbidity classification from social media posts. Unlike contemporary datasets that often oversimplify the intricate interplay between different mental health disorders by treating them as isolated conditions, ANGST enables multi-label classification, allowing each post to be simultaneously identified as indicating depression and/or anxiety. Comprising 2876 meticulously annotated posts by expert psychologists and an additional 7667 silver-labeled posts, ANGST posits a more representative sample of online mental health discourse. Moreover, we benchmark ANGST using various state-of-the-art language models, ranging from Mental-BERT to GPT-4. Our results provide significant insights into the capabilities and limitations of these models in complex diagnostic scenarios. While GPT-4 generally outperforms other models, none achieve an F1 score exceeding 72% in multi-class comorbid classification, underscoring the ongoing challenges in applying language models to mental health diagnostics.
Key facts. Cited by 12 papers in the map (data through 14 Oct 2026). Builds on 32 of its 83 references that are in the map. First posted on arXiv 4 Oct 2024.
Builds on
32 of 83 references.
References · 32
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20 more
- 2017Depression and Self-Harm Risk Assessment in Online Forumscited by 84
- 2019Dreaddit: A Reddit Dataset for Stress Analysis in Social Mediacited by 81
- 2018SMHD: A Large-Scale Resource for Exploring Online Language Usage for Multiple Mental Health Conditionscited by 73
- 2023Mental-LLM: Leveraging Large Language Models for Mental Health Prediction via Online Text Datacited by 66
- 2023MentaLLaMA: Interpretable Mental Health Analysis on Social Media with Large Language Modelscited by 63
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Built on by
Citing papers per year: 2025: 7; 2026: 5.
12 papers.
- 2025A Survey of Large Language Models in Psychotherapy: Current Landscape and Future Directionscited by 12
- 2025MHQA: A Diverse, Knowledge Intensive Mental Health Question Answering Challenge for Language Modelscited by 7
- 2025ProMind-LLM: Proactive Mental Health Care via Causal Reasoning with Sensor Datacited by 6
- 2025FedMentor: Domain-Aware Differential Privacy for Heterogeneous Federated LLMs in Mental Healthcited by 5
- 2025A Multi-Level Benchmark for Causal Language Understanding in Social Media Discoursecited by 3
- 2025ReDepress: A Cognitive Framework for Detecting Depression Relapse from Social Mediacited by 2
- 2025It Hears, It Sees too: Multi-Modal LLM for Depression Detection By Integrating Visual Understanding into Audio Language Modelscited by 2
- 2026Responsible Evaluation of AI for Mental Healthcited by 2
- 2026OMIND: Framework for Knowledge Grounded Finetuning and Multi-Turn Dialogue Benchmark for Mental Health LLMscited by 1
- 2026When PCOS Meets Eating Disorders: An Explainable AI Approach to Detecting the Hidden Triple Burdencited by 0
- 2026The MADRS Pipeline: Supporting Depression Assessment in Clinical Trialscited by 0
- 2026From Pattern Recognizers to Personalized Companions: A Survey of Large Language Models in Mental Healthcited by 0
- 2026From Pattern Recognizers to Personalized Companions: A Survey of Large Language Models in Mental Health21 Sep 2026
- 2026The MADRS Pipeline: Supporting Depression Assessment in Clinical Trials30 Jul 2026
- 2026When PCOS Meets Eating Disorders: An Explainable AI Approach to Detecting the Hidden Triple Burden15 Apr 2026
- 2026OMIND: Framework for Knowledge Grounded Finetuning and Multi-Turn Dialogue Benchmark for Mental Health LLMs26 Mar 2026
- 2026Responsible Evaluation of AI for Mental Health20 Jan 2026
- 2025It Hears, It Sees too: Multi-Modal LLM for Depression Detection By Integrating Visual Understanding into Audio Language Models25 Nov 2025
- 2025ReDepress: A Cognitive Framework for Detecting Depression Relapse from Social Media22 Sep 2025
- 2025A Multi-Level Benchmark for Causal Language Understanding in Social Media Discourse20 Sep 2025
- 2025FedMentor: Domain-Aware Differential Privacy for Heterogeneous Federated LLMs in Mental Health16 Sep 2025
- 2025ProMind-LLM: Proactive Mental Health Care via Causal Reasoning with Sensor Data20 May 2025
- 2025MHQA: A Diverse, Knowledge Intensive Mental Health Question Answering Challenge for Language Models21 Feb 2025
- 2025A Survey of Large Language Models in Psychotherapy: Current Landscape and Future Directions16 Feb 2025