EM-Net: Efficient Channel and Frequency Learning with Mamba for 3D Medical Image Segmentation
On the map: State-space sequence models (S4, Mamba) → Mamba for medical image analysis
Abstract (arXiv)
Convolutional neural networks have primarily led 3D medical image segmentation but may be limited by small receptive fields. Transformer models excel in capturing global relationships through self-attention but are challenged by high computational costs at high resolutions. Recently, Mamba, a state space model, has emerged as an effective approach for sequential modeling. Inspired by its success, we introduce a novel Mamba-based 3D medical image segmentation model called EM-Net. It not only efficiently captures attentive interaction between regions by integrating and selecting channels, but also effectively utilizes frequency domain to harmonize the learning of features across varying scales, while accelerating training speed. Comprehensive experiments on two challenging multi-organ datasets with other state-of-the-art (SOTA) algorithms show that our method exhibits better segmentation accuracy while requiring nearly half the parameter size of SOTA models and 2x faster training speed.
Key facts. Cited by 12 papers in the map (data through 7 Oct 2026). Placed in Mamba for medical image analysis, one of 10 directions in State-space sequence models (S4, Mamba). Builds on 17 of its 21 references that are in the map. First posted on arXiv 26 Sep 2024.
Builds on
17 of 21 references.
Closest ancestors · 1
Same direction, newest first
Other references · 16
- 2017Attention Is All You Needcited by 59,932
- 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 29,915
- 2023Mamba: Linear-Time Sequence Modeling with Selective State Spacescited by 4,616
- 2021Efficiently Modeling Long Sequences with Structured State Spacescited by 2,424
- 20163D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotationcited by 1,471
- 2024Vision Mamba: Efficient Visual Representation Learning with Bidirectional State Space Modelcited by 1,051
- 2024VMamba: Visual State Space Modelcited by 955
- 2021UNETR: Transformers for 3D Medical Image Segmentationcited by 954
- 2022Swin UNETR: Swin Transformers for Semantic Segmentation of Brain Tumors in MRI Imagescited by 823
- 2021Combining Recurrent, Convolutional, and Continuous-time Models with Linear State-Space Layerscited by 607
- 20183D MRI brain tumor segmentation using autoencoder regularizationcited by 324
- 20223D UX-Net: A Large Kernel Volumetric ConvNet Modernizing Hierarchical Transformer for Medical Image Segmentationcited by 94
4 more
- 2021A Robust Volumetric Transformer for Accurate 3D Tumor Segmentationcited by 41
- 2023Diff-UNet: A Diffusion Embedded Network for Volumetric Segmentationcited by 41
- 20233D TransUNet: Advancing Medical Image Segmentation through Vision Transformerscited by 20
- 2023FreMIM: Fourier Transform Meets Masked Image Modeling for Medical Image Segmentationcited by 10
Built on by
Citing papers per year: 2025: 10; 2026: 2.
12 papers.
- 2025A Comprehensive Analysis of Mamba for 3D Volumetric Medical Image Segmentationcited by 4
- 2025Universal Vessel Segmentation for Multi-Modality Retinal Imagescited by 3
- 2025Mamba Goes HoME: Hierarchical Soft Mixture-of-Experts for 3D Medical Image Segmentationcited by 3
- 2025SparseMamba-PCL: Scribble-Supervised Medical Image Segmentation via SAM-Guided Progressive Collaborative Learningcited by 2
- 2025Self is the Best Learner: CT-free Ultra-Low-Dose PET Organ Segmentation via Collaborating Denoising and Segmentation Learningcited by 2
- 2025FaRMamba: Frequency-based learning and Reconstruction aided Mamba for Medical Segmentationcited by 0
- 2025SSFMamba: Learning Symmetry-driven Spatial-Frequency Modeling for Physically Consistent 3D Medical Image Segmentationcited by 0
- 2025MSD-KMamba: Bidirectional Spatial-Aware Multi-Modal 3D Brain Segmentation via Multi-scale Self-Distilled Fusion Strategycited by 0
- 2025TSkel-Mamba: Temporal Dynamic Modeling via State Space Model for Human Skeleton-based Action Recognitioncited by 0
- 2025SwinTF3D: A Lightweight Multimodal Fusion Approach for Text-Guided 3D Medical Image Segmentationcited by 0
- 2026Benchmarking CNN-based Models against Transformer-based Models for Abdominal Multi-Organ Segmentation on the RATIC Datasetcited by 0
- 2026TEAMS: Text-prompted spatiotEmporal dual-heAd Mamba Snakecited by 0
- 2026TEAMS: Text-prompted spatiotEmporal dual-heAd Mamba Snake18 Aug 2026
- 2026Benchmarking CNN-based Models against Transformer-based Models for Abdominal Multi-Organ Segmentation on the RATIC Dataset19 Mar 2026
- 2025SwinTF3D: A Lightweight Multimodal Fusion Approach for Text-Guided 3D Medical Image Segmentation28 Dec 2025
- 2025TSkel-Mamba: Temporal Dynamic Modeling via State Space Model for Human Skeleton-based Action Recognition12 Dec 2025
- 2025MSD-KMamba: Bidirectional Spatial-Aware Multi-Modal 3D Brain Segmentation via Multi-scale Self-Distilled Fusion Strategy28 Sep 2025
- 2025SSFMamba: Learning Symmetry-driven Spatial-Frequency Modeling for Physically Consistent 3D Medical Image Segmentation5 Aug 2025
- 2025FaRMamba: Frequency-based learning and Reconstruction aided Mamba for Medical Segmentation26 Jul 2025
- 2025Mamba Goes HoME: Hierarchical Soft Mixture-of-Experts for 3D Medical Image Segmentation8 Jul 2025
- 2025A Comprehensive Analysis of Mamba for 3D Volumetric Medical Image Segmentation25 Mar 2025
- 2025Self is the Best Learner: CT-free Ultra-Low-Dose PET Organ Segmentation via Collaborating Denoising and Segmentation Learning5 Mar 2025
- 2025SparseMamba-PCL: Scribble-Supervised Medical Image Segmentation via SAM-Guided Progressive Collaborative Learning3 Mar 2025
- 2025Universal Vessel Segmentation for Multi-Modality Retinal Images10 Feb 2025
Similar, not cited
Close in wording, no citation either way
- 2024MambaClinix: Hierarchical Gated Convolution and Mamba-Based U-Net for Enhanced 3D Medical Image Segmentation
- 2024Taming Mambas for Voxel Level 3D Medical Image Segmentation
- 2025Prompt-Guided Dual-Path UNet with Mamba for Medical Image Segmentation
- 2024Swin-UMamba: Mamba-based UNet with ImageNet-based pretraining
- 2024Mamba-UNet: UNet-Like Pure Visual Mamba for Medical Image Segmentation
- 2025MambaVesselNet++: A Hybrid CNN-Mamba Architecture for Medical Image Segmentation
- 2024A Comprehensive Survey of Mamba Architectures for Medical Image Analysis: Classification, Segmentation, Restoration and Beyond
- 2026A Hybrid Mamba-SAM Architecture for Efficient 3D Medical Image Segmentation