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Benchmarking CNN-based Models against Transformer-based Models for Abdominal Multi-Organ Segmentation on the RATIC Dataset

arXiv 2603.18616 ↗First posted 19 Mar 2026cs.CVcited by 0

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Abstract (arXiv)

Accurate multi-organ segmentation in abdominal CT scans is essential for computer-aided diagnosis and treatment. While convolutional neural networks (CNNs) have long been the standard approach in medical image segmentation, transformer-based architectures have recently gained attention due to their ability to model long-range dependencies. In this study, we systematically benchmark the three hybrid transformer-based models UNETR, SwinUNETR, and UNETR++ against a strong CNN baseline, SegResNet, for volumetric multi-organ segmentation on the heterogeneous RATIC dataset. The dataset comprises 206 annotated CT scans from 23 institutions worldwide, covering five abdominal organs. All models were trained and evaluated under identical preprocessing and training conditions using the Dice Similarity Coefficient (DSC) as the primary metric. The results show that the CNN-based SegResNet achieves the highest overall performance, outperforming all hybrid transformer-based models across all organs. Among the transformer-based approaches, UNETR++ delivers the most competitive results, while UNETR demonstrates notably faster convergence with fewer training iterations. These findings suggest that, for small- to medium-sized heterogeneous datasets, well-optimized CNN architectures remain highly competitive and may outperform hybrid transformer-based designs.

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References · 16

  1. 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 29,915
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  5. 2022Swin UNETR: Swin Transformers for Semantic Segmentation of Brain Tumors in MRI Imagescited by 823
  6. 2022TotalSegmentator: robust segmentation of 104 anatomical structures in CT imagescited by 597
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  8. 2021Self-Supervised Pre-Training of Swin Transformers for 3D Medical Image Analysiscited by 418
  9. 20183D MRI brain tumor segmentation using autoencoder regularizationcited by 324
  10. 2018nnU-Net: Self-adapting Framework for U-Net-Based Medical Image Segmentationcited by 291
  11. 2024nnU-Net Revisited: A Call for Rigorous Validation in 3D Medical Image Segmentationcited by 235
  12. 2022UNETR++: Delving into Efficient and Accurate 3D Medical Image Segmentationcited by 112
4 more
  1. 2023HybridMIM: A Hybrid Masked Image Modeling Framework for 3D Medical Image Segmentationcited by 12
  2. 2024The RSNA Abdominal Traumatic Injury CT (RATIC) Datasetcited by 12
  3. 2024EM-Net: Efficient Channel and Frequency Learning with Mamba for 3D Medical Image Segmentationcited by 12
  4. 2025SegResMamba: An Efficient Architecture for 3D Medical Image Segmentationcited by 2

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