mlsanityData to 7 Oct 2026

Uni-Med: A Unified Medical Generalist Foundation Model For Multi-Task Learning Via Connector-MoE

arXiv 2409.17508 ↗First posted 26 Sep 2024cs.CV cs.AI cs.LGcited by 18

On the map: Multimodal LLMs / vision-language models → Medical vision-language models

also in 1 more
Abstract (arXiv)

Multi-modal large language models (MLLMs) have shown impressive capabilities as a general-purpose interface for various visual and linguistic tasks. However, building a unified MLLM for multi-task learning in the medical field remains a thorny challenge. To mitigate the tug-of-war problem of multi-modal multi-task optimization in MLLMs, recent advances primarily focus on improving the LLM components, while neglecting the connector that bridges the gap between modalities. In this paper, we introduce Uni-Med, a novel medical generalist foundation model which consists of a universal visual feature extraction module, a connector mixture-of-experts (CMoE) module, and an LLM. Benefiting from the proposed CMoE that leverages a well-designed router with a mixture of projection experts at the connector, Uni-Med achieves efficient solution to the tug-of-war problem and can perform six different medical tasks including question answering, visual question answering, report generation, referring expression comprehension, referring expression generation and image classification. To the best of our knowledge, Uni-Med is the first effort to tackle multi-task interference at the connector in MLLMs. Extensive ablation experiments validate the effectiveness of introducing CMoE under any configuration, with up to an average 8% performance gains. We further provide interpretation analysis of the tug-of-war problem from the perspective of gradient optimization and parameter statistics. Compared to previous state-of-the-art medical MLLMs, Uni-Med achieves competitive or superior evaluation metrics on diverse tasks. Code and resources are available at https://github.com/tsinghua-msiip/Uni-Med.

Key facts. Cited by 18 papers in the map (data through 7 Oct 2026). Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 50 of its 65 references that are in the map. First posted on arXiv 26 Sep 2024.

Builds on

50 of 65 references.

Closest ancestors · 3

Same direction, newest first

  1. 2024CARES: A Comprehensive Benchmark of Trustworthiness in Medical Vision Language Models10 Jun
  2. 2024Worse than Random? An Embarrassingly Simple Probing Evaluation of Large Multimodal Models in Medical VQA30 May
  3. 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day1 Jun

Other references · 47

  1. 2023GPT-4 Technical Reportcited by 18,132
  2. 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,084
  3. 2023Llama 2: Open Foundation and Fine-Tuned Chat Modelscited by 12,865
  4. 2023Visual Instruction Tuningcited by 7,792
  5. 2023BLIP-2: Bootstrapping Language-Image Pre-training with Frozen Image Encoders and Large Language Modelscited by 6,069
  6. 2023Improved Baselines with Visual Instruction Tuningcited by 4,362
  7. 2022Flamingo: a Visual Language Model for Few-Shot Learningcited by 4,337
  8. 2022BLIP: Bootstrapping Language-Image Pre-training for Unified Vision-Language Understanding and Generationcited by 4,310
  9. 2021Switch Transformers: Scaling to Trillion Parameter Models with Simple and Efficient Sparsitycited by 3,014
  10. 2023MiniGPT-4: Enhancing Vision-Language Understanding with Advanced Large Language Modelscited by 2,689
  11. 2024Mixtral of Expertscited by 1,785
  12. 2020What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Examscited by 1,324
35 more
  1. 2019PubMedQA: A Dataset for Biomedical Research Question Answeringcited by 1,271
  2. 2020Gradient Surgery for Multi-Task Learningcited by 1,210
  3. 2023Kosmos-2: Grounding Multimodal Large Language Models to the Worldcited by 1,075
  4. 2023mPLUG-Owl: Modularization Empowers Large Language Models with Multimodalitycited by 1,038
  5. 2023ShareGPT4V: Improving Large Multi-Modal Models with Better Captionscited by 1,000
  6. 2021Scaling Vision with Sparse Mixture of Expertscited by 740
  7. 2021MedMNIST v2 -- A large-scale lightweight benchmark for 2D and 3D biomedical image classificationcited by 682
  8. 2019Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)cited by 657
  9. 2023MiniGPT-v2: large language model as a unified interface for vision-language multi-task learningcited by 617
  10. 2023OpenFlamingo: An Open-Source Framework for Training Large Autoregressive Vision-Language Modelscited by 560
  11. 2023mPLUG-Owl2: Revolutionizing Multi-modal Large Language Model with Modality Collaborationcited by 545
  12. 2019The Liver Tumor Segmentation Benchmark (LiTS)cited by 504
  13. 2020PathVQA: 30000+ Questions for Medical Visual Question Answeringcited by 467
  14. 2021SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answeringcited by 444
  15. 2022Unified-IO: A Unified Model for Vision, Language, and Multi-Modal Taskscited by 420
  16. 2023Med-Flamingo: a Multimodal Medical Few-shot Learnercited by 387
  17. 2023PandaGPT: One Model To Instruction-Follow Them Allcited by 330
  18. 2021RadGraph: Extracting Clinical Entities and Relations from Radiology Reportscited by 310
  19. 2023Unified-IO 2: Scaling Autoregressive Multimodal Models with Vision, Language, Audio, and Actioncited by 301
  20. 2024MoE-LLaVA: Mixture of Experts for Large Vision-Language Modelscited by 298
  21. 2023Towards Generalist Biomedical AIcited by 286
  22. 2020Just Pick a Sign: Optimizing Deep Multitask Models with Gradient Sign Dropoutcited by 199
  23. 2023Towards Generalist Foundation Model for Radiology by Leveraging Web-scale 2D&3D Medical Datacited by 176
  24. 2023Macaw-LLM: Multi-Modal Language Modeling with Image, Audio, Video, and Text Integrationcited by 168
  25. 2022A Unified Sequence Interface for Vision Taskscited by 152
  26. 2023Pushing Mixture of Experts to the Limit: Extremely Parameter Efficient MoE for Instruction Tuningcited by 148
  27. 2023X-LLM: Bootstrapping Advanced Large Language Models by Treating Multi-Modalities as Foreign Languagescited by 127
  28. 2023When MOE Meets LLMs: Parameter Efficient Fine-tuning for Multi-task Medical Applicationscited by 110
  29. 2023Mixture of Cluster-conditional LoRA Experts for Vision-language Instruction Tuningcited by 106
  30. 2024LLaVA-MoLE: Sparse Mixture of LoRA Experts for Mitigating Data Conflicts in Instruction Finetuning MLLMscited by 84
  31. 2023Can GPT-4V(ision) Serve Medical Applications? Case Studies on GPT-4V for Multimodal Medical Diagnosiscited by 77
  32. 2022Uni-Perceiver-MoE: Learning Sparse Generalist Models with Conditional MoEscited by 58
  33. 2023SA-Med2D-20M Dataset: Segment Anything in 2D Medical Imaging with 20 Million maskscited by 54
  34. 2024MTLoRA: A Low-Rank Adaptation Approach for Efficient Multi-Task Learningcited by 44
  35. 2018The HAM10000 dataset, a large collection of multi-source dermatoscopic images of common pigmented skin lesionscited by 26

Built on by

Cited by year (2026 to 7 Oct)

Citing papers per year: 2024: 1; 2025: 8; 2026: 9.

18 papers.

Sort:

By area:

  1. 2024Med-2E3: A 2D-Enhanced 3D Medical Multimodal Large Language Modelcited by 15
  2. 2025MediSee: Reasoning-based Pixel-level Perception in Medical Imagescited by 8
  3. 2025Connector-S: A Survey of Connectors in Multi-modal Large Language Modelscited by 7
  4. 2025Structure Causal Models and LLMs Integration in Medical Visual Question Answeringcited by 6
  5. 2025TableMoE: Neuro-Symbolic Routing for Structured Expert Reasoning in Multimodal Table Understandingcited by 6
  6. 2025MedM-VL: What Makes a Good Medical LVLM?cited by 4
  7. 2025Omni-AVSR: Towards Unified Multimodal Speech Recognition with Large Language Modelscited by 3
  8. 2025Enhancing Multi-task Learning Capability of Medical Generalist Foundation Model via Image-centric Multi-annotation Datacited by 1
  9. 2025Improving Medical Visual Representation Learning with Pathological-level Cross-Modal Alignment and Correlation Explorationcited by 1
  10. 2026Modeling Cross-vision Synergy for Unified Large Vision Modelcited by 1
  11. 2026Lost in the Hype: Revealing and Dissecting the Performance Degradation of Medical Multimodal Large Language Models in Image Classificationcited by 1
  12. 2026UniBioTransfer: A Unified Framework for Multiple Biometrics Transfercited by 0
6 more
  1. 2026M-IDoL: Information Decomposition for Modality-Specific and Diverse Representation Learning in Medical Foundation Modelcited by 0
  2. 2026GRCD: Grounded Region Change Detection for Multi-Finding Chest X-Ray Pairscited by 0
  3. 2026iLENS: Interpretable LLM-Guided Mixture-of-Experts for Neuroimaging Survival Analysiscited by 0
  4. 2026UniMedSeg: Unified In-Context Learning for Multi-Paradigm 2D/3D Medical Image Segmentationcited by 0
  5. 2026Hierarchical Wasserstein Merging for Multi-Domain Multi-Task Learning: From Specialists to a Generalistcited by 0
  6. 2026Med-RADIO: Reducing All Medical Domains Into One via Multi-Teacher Distillationcited by 0

Similar, not cited

Close in wording, no citation either way

  1. 2024MING-MOE: Enhancing Medical Multi-Task Learning in Large Language Models with Sparse Mixture of Low-Rank Adapter Experts
  2. 2024Med-MoE: Mixture of Domain-Specific Experts for Lightweight Medical Vision-Language Models
  3. 2025SMMILE: An Expert-Driven Benchmark for Multimodal Medical In-Context Learning
  4. 2025Medical Large Vision Language Models with Multi-Image Visual Ability
  5. 2024Fusion of Domain-Adapted Vision and Language Models for Medical Visual Question Answering
  6. 2024Towards a Multimodal Large Language Model with Pixel-Level Insight for Biomedicine
  7. 2023UniDCP: Unifying Multiple Medical Vision-language Tasks via Dynamic Cross-modal Learnable Prompts
  8. 2025CMI-MTL: Cross-Mamba interaction based multi-task learning for medical visual question answering