Medical Large Vision Language Models with Multi-Image Visual Ability
On the map: Multimodal LLMs / vision-language models → Medical vision-language models
Abstract (arXiv)
Medical large vision-language models (LVLMs) have demonstrated promising performance across various single-image question answering (QA) benchmarks, yet their capability in processing multi-image clinical scenarios remains underexplored. Unlike single image based tasks, medical tasks involving multiple images often demand sophisticated visual understanding capabilities, such as temporal reasoning and cross-modal analysis, which are poorly supported by current medical LVLMs. To bridge this critical gap, we present the Med-MIM instruction dataset, comprising 83.2K medical multi-image QA pairs that span four types of multi-image visual abilities (temporal understanding, reasoning, comparison, co-reference). Using this dataset, we fine-tune Mantis and LLaVA-Med, resulting in two specialized medical VLMs: MIM-LLaVA-Med and Med-Mantis, both optimized for multi-image analysis. Additionally, we develop the Med-MIM benchmark to comprehensively evaluate the medical multi-image understanding capabilities of LVLMs. We assess eight popular LVLMs, including our two models, on the Med-MIM benchmark. Experimental results show that both Med-Mantis and MIM-LLaVA-Med achieve superior performance on the held-in and held-out subsets of the Med-MIM benchmark, demonstrating that the Med-MIM instruction dataset effectively enhances LVLMs' multi-image understanding capabilities in the medical domain.
Key facts. Cited by 8 papers in the map (data through 14 Oct 2026). Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 16 of its 27 references that are in the map. First posted on arXiv 25 May 2025.
Builds on
16 of 27 references.
Closest ancestors · 3
Same direction, newest first
- 2024Unlocking the Power of Spatial and Temporal Information in Medical Multimodal Pre-training30 May
- 2024M3D: Advancing 3D Medical Image Analysis with Multi-Modal Large Language Models31 Mar
- 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day1 Jun
Other references · 13
- 2023Visual Instruction Tuningcited by 7,869
- 2024GPT-4o System Cardcited by 4,588
- 2023InternVL: Scaling up Vision Foundation Models and Aligning for Generic Visual-Linguistic Taskscited by 2,565
- 2024DeepSeek-VL: Towards Real-World Vision-Language Understandingcited by 733
- 2023Med-Flamingo: a Multimodal Medical Few-shot Learnercited by 392
- 2023PMC-VQA: Visual Instruction Tuning for Medical Visual Question Answeringcited by 338
- 2024MANTIS: Interleaved Multi-Image Instruction Tuningcited by 216
- 2023Towards Generalist Foundation Model for Radiology by Leveraging Web-scale 2D&3D Medical Datacited by 179
- 2024MMDU: A Multi-Turn Multi-Image Dialog Understanding Benchmark and Instruction-Tuning Dataset for LVLMscited by 90
- 2023Quilt-LLaVA: Visual Instruction Tuning by Extracting Localized Narratives from Open-Source Histopathology Videoscited by 86
- 2024MMIU: Multimodal Multi-image Understanding for Evaluating Large Vision-Language Modelscited by 67
- 2024Procedure-Aware Surgical Video-language Pretraining with Hierarchical Knowledge Augmentationcited by 39
Built on by
Citing papers per year: 2025: 2; 2026: 6.
8 papers.
- 2025MoMA: A Mixture-of-Multimodal-Agents Architecture for Enhancing Clinical Prediction Modellingcited by 7
- 2026Correcting Visual Blur Induced by Attention Distraction to Reduce Hallucinations: Algorithm and Theorycited by 3
- 2025See-in-Pairs: Reference Image-Guided Comparative Vision-Language Models for Medical Diagnosiscited by 2
- 2026Do All Individual Layers Help? An Empirical Study of Task-Interfering Layers in Vision-Language Modelscited by 2
- 2026Location-Aware Pretraining for Medical Difference Visual Question Answeringcited by 1
- 2026Robust Pre-Training of Medical Vision-and-Language Models with Domain-Invariant Multi-Modal Masked Reconstructioncited by 0
- 2026MEDSYN: Benchmarking Multi-EviDence SYNthesis in Complex Clinical Cases for Multimodal Large Language Modelscited by 0
- 2026Beyond Attention Imbalance: Mitigating Hallucinations via Spectral Surgerycited by 0
- 2026Beyond Attention Imbalance: Mitigating Hallucinations via Spectral Surgery29 Sep 2026
- 2026Correcting Visual Blur Induced by Attention Distraction to Reduce Hallucinations: Algorithm and Theory23 May 2026
- 2026Location-Aware Pretraining for Medical Difference Visual Question Answering5 Mar 2026
- 2026MEDSYN: Benchmarking Multi-EviDence SYNthesis in Complex Clinical Cases for Multimodal Large Language Models25 Feb 2026
- 2026Robust Pre-Training of Medical Vision-and-Language Models with Domain-Invariant Multi-Modal Masked Reconstruction6 Feb 2026
- 2026Do All Individual Layers Help? An Empirical Study of Task-Interfering Layers in Vision-Language Models1 Feb 2026
- 2025MoMA: A Mixture-of-Multimodal-Agents Architecture for Enhancing Clinical Prediction Modelling7 Aug 2025
- 2025See-in-Pairs: Reference Image-Guided Comparative Vision-Language Models for Medical Diagnosis22 Jun 2025
Similar, not cited
Close in wording, no citation either way
- 2024Fusion of Domain-Adapted Vision and Language Models for Medical Visual Question Answering
- 2024OmniMedVQA: A New Large-Scale Comprehensive Evaluation Benchmark for Medical LVLM
- 2024Towards a Multimodal Large Language Model with Pixel-Level Insight for Biomedicine
- 2024Beyond the Hype: A dispassionate look at vision-language models in medical scenario
- 2025MIMO: A medical vision language model with visual referring multimodal input and pixel grounding multimodal output
- 2024Targeted Visual Prompting for Medical Visual Question Answering
- 2026Analyzing and Mitigating Cross-Lingual Degradation in Multilingual Medical VQA
- 2025MedM-VL: What Makes a Good Medical LVLM?