MediSee: Reasoning-based Pixel-level Perception in Medical Images
Not on the map. Why?
Abstract (arXiv)
Despite remarkable advancements in pixel-level medical image perception, existing methods are either limited to specific tasks or heavily rely on accurate bounding boxes or text labels as input prompts. However, the medical knowledge required for input is a huge obstacle for general public, which greatly reduces the universality of these methods. Compared with these domain-specialized auxiliary information, general users tend to rely on oral queries that require logical reasoning. In this paper, we introduce a novel medical vision task: Medical Reasoning Segmentation and Detection (MedSD), which aims to comprehend implicit queries about medical images and generate the corresponding segmentation mask and bounding box for the target object. To accomplish this task, we first introduce a Multi-perspective, Logic-driven Medical Reasoning Segmentation and Detection (MLMR-SD) dataset, which encompasses a substantial collection of medical entity targets along with their corresponding reasoning. Furthermore, we propose MediSee, an effective baseline model designed for medical reasoning segmentation and detection. The experimental results indicate that the proposed method can effectively address MedSD with implicit colloquial queries and outperform traditional medical referring segmentation methods.
Key facts. Cited by 8 papers in the map (data through 14 Oct 2026). Builds on 24 of its 50 references that are in the map. First posted on arXiv 15 Apr 2025.
Builds on
24 of 50 references.
References · 24
- 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,380
- 2023Segment Anythingcited by 8,234
- 2023Grounding DINO: Marrying DINO with Grounded Pre-Training for Open-Set Object Detectioncited by 3,332
- 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Daycited by 1,305
- 2025Janus-Pro: Unified Multimodal Understanding and Generation with Data and Model Scalingcited by 812
- 2021The Medical Segmentation Decathloncited by 628
- 2021The RSNA-ASNR-MICCAI BraTS 2021 Benchmark on Brain Tumor Segmentation and Radiogenomic Classificationcited by 518
- 2021Image Segmentation Using Text and Image Promptscited by 512
- 2023GLaMM: Pixel Grounding Large Multimodal Modelcited by 455
- 2023Segment Anything in Medical Imagescited by 227
- 2016Validation, comparison, and combination of algorithms for automatic detection of pulmonary nodules in computed tomography images: the LUNA16 challengecited by 201
- 2020Medical Image Segmentation Using Deep Learning: A Surveycited by 164
12 more
- 2016The Importance of Skip Connections in Biomedical Image Segmentationcited by 126
- 2023The KiTS21 Challenge: Automatic segmentation of kidneys, renal tumors, and renal cysts in corticomedullary-phase CTcited by 103
- 2023SegVol: Universal and Interactive Volumetric Medical Image Segmentationcited by 87
- 2016DeepCut: Object Segmentation from Bounding Box Annotations using Convolutional Neural Networkscited by 79
- 2023SA-Med2D-20M Dataset: Segment Anything in 2D Medical Imaging with 20 Million maskscited by 55
- 2024LLM-Seg: Bridging Image Segmentation and Large Language Model Reasoningcited by 52
- 2023ScribblePrompt: Fast and Flexible Interactive Segmentation for Any Biomedical Imagecited by 48
- 2024Interactive Medical Image Segmentation: A Benchmark Dataset and Baselinecited by 30
- 2019Intracranial Hemorrhage Segmentation Using Deep Convolutional Modelcited by 29
- 2025MMR: A Large-scale Benchmark Dataset for Multi-target and Multi-granularity Reasoning Segmentationcited by 28
- 2024Uni-Med: A Unified Medical Generalist Foundation Model For Multi-Task Learning Via Connector-MoEcited by 19
- 2018Organ at Risk Segmentation in Head and Neck CT Images by Using a Two-Stage Segmentation Framework Based on 3D U-Netcited by 9
Built on by
Citing papers per year: 2025: 5; 2026: 3.
8 papers.
- 2025MedReasoner: Reinforcement Learning Drives Reasoning Grounding from Clinical Thought to Pixel-Level Precisioncited by 10
- 2026IBISAgent: Reinforcing Pixel-Level Visual Reasoning in MLLMs for Universal Biomedical Object Referring and Segmentationcited by 10
- 2025SAMPO-Path: Segmentation Intent-Aligned Preference Optimization for Pathology Foundation Model Segmentationcited by 2
- 2025Sim4Seg: Boosting Multimodal Multi-disease Medical Diagnosis Segmentation with Region-Aware Vision-Language Similarity Maskscited by 2
- 2025MediRound: Multi-Round Entity-Level Reasoning Segmentation in Medical Imagescited by 1
- 2025Unlocking the Forgery Detection Potential of Vanilla MLLMs: A Novel Training-Free Pipelinecited by 0
- 2026MedVeriSeg: Teaching LISA-Like Medical Segmentation Models to Verify Query Validity Without Extra Trainingcited by 0
- 2026MedUP: Awakening Unified Understanding and Perception in Medical Vision-Language Modelscited by 0
- 2026MedUP: Awakening Unified Understanding and Perception in Medical Vision-Language Models11 Aug 2026
- 2026MedVeriSeg: Teaching LISA-Like Medical Segmentation Models to Verify Query Validity Without Extra Training11 Apr 2026
- 2026IBISAgent: Reinforcing Pixel-Level Visual Reasoning in MLLMs for Universal Biomedical Object Referring and Segmentation6 Jan 2026
- 2025Unlocking the Forgery Detection Potential of Vanilla MLLMs: A Novel Training-Free Pipeline17 Nov 2025
- 2025MediRound: Multi-Round Entity-Level Reasoning Segmentation in Medical Images15 Nov 2025
- 2025Sim4Seg: Boosting Multimodal Multi-disease Medical Diagnosis Segmentation with Region-Aware Vision-Language Similarity Masks10 Nov 2025
- 2025MedReasoner: Reinforcement Learning Drives Reasoning Grounding from Clinical Thought to Pixel-Level Precision11 Aug 2025
- 2025SAMPO-Path: Segmentation Intent-Aligned Preference Optimization for Pathology Foundation Model Segmentation4 Aug 2025
Similar, not cited
Close in wording, no citation either way
- 2025MedSeg-R: Reasoning Segmentation in Medical Images with Multimodal Large Language Models
- 2026MedPixel: A Unified Pixel-Language Model for Medical Reasoning and Segmentation
- 2025PRS-Med: Position Reasoning Segmentation in Medical Imaging
- 2026Beyond Visual Cues: CoT-Enhanced Reasoning for Semi-supervised Medical Image Segmentation
- 2026SAM Meets VLM: Parameter-Decoupled Full-Parameter Training for Unified Medical Reasoning and Segmentation
- 2026ReXInTheWild: A Unified Benchmark for Medical Photograph Understanding
- 2026MedVL-SAM2: A unified 3D medical vision-language model for multimodal reasoning and prompt-driven segmentation
- 2026MedSIGHT: Towards Grounded Visual Comprehension in Medical Large Vision-Language Models