Assessing Empathy in Large Language Models with Real-World Physician-Patient Interactions
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Abstract (arXiv)
The integration of Large Language Models (LLMs) into the healthcare domain has the potential to significantly enhance patient care and support through the development of empathetic, patient-facing chatbots. This study investigates an intriguing question Can ChatGPT respond with a greater degree of empathy than those typically offered by physicians? To answer this question, we collect a de-identified dataset of patient messages and physician responses from Mayo Clinic and generate alternative replies using ChatGPT. Our analyses incorporate novel empathy ranking evaluation (EMRank) involving both automated metrics and human assessments to gauge the empathy level of responses. Our findings indicate that LLM-powered chatbots have the potential to surpass human physicians in delivering empathetic communication, suggesting a promising avenue for enhancing patient care and reducing professional burnout. The study not only highlights the importance of empathy in patient interactions but also proposes a set of effective automatic empathy ranking metrics, paving the way for the broader adoption of LLMs in healthcare.
Key facts. Cited by 13 papers in the map (data through 7 Oct 2026). Builds on 25 of its 59 references that are in the map. First posted on arXiv 26 May 2024.
Builds on
25 of 59 references.
References · 25
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13 more
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Citing papers per year: 2024: 3; 2025: 6; 2026: 4.
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- 2025HumaniBench: A Human-Centric Framework for Large Multimodal Models Evaluationcited by 19
- 2024Script-Strategy Aligned Generation: Aligning LLMs with Expert-Crafted Dialogue Scripts and Therapeutic Strategies for Psychotherapycited by 7
- 2025Benchmarking Generative AI for Scoring Medical Student Interviews in Objective Structured Clinical Examinations (OSCEs)cited by 7
- 2025RECAP: Transparent Inference-Time Emotion Alignment for Medical Dialogue Systemscited by 3
- 2024The use of GPT-4o and Other Large Language Models for the Improvement and Design of Self-Assessment Scales for Measurement of Interpersonal Communication Skillscited by 1
- 2024A Multi-Agent Dual Dialogue System to Support Mental Health Care Providerscited by 1
- 2025SocialLM: Social Signal Processing of Patient-Provider Communication using LLMs and Contextual Aggregationcited by 1
- 2025Empathy by Design: Aligning Large Language Models for Healthcare Dialoguecited by 1
- 2025Context-Emotion Aware Therapeutic Dialogue Generation: A Multi-component Reinforcement Learning Approach to Language Models for Mental Health Supportcited by 0
- 2026From Generation to Collaboration: Using LLMs to Edit for Empathy in Healthcarecited by 0
- 2026LLMs Should Incorporate Explicit Mechanisms for Human Empathycited by 0
- 2026Can "AI" Be a Doctor? A Study of Empathy, Readability, and Alignment in Clinical LLMscited by 0
1 more
- 2026Appropriateness of Empathy in AI: A Signal-Cost Perspective29 May 2026
- 2026Can "AI" Be a Doctor? A Study of Empathy, Readability, and Alignment in Clinical LLMs22 Apr 2026
- 2026LLMs Should Incorporate Explicit Mechanisms for Human Empathy12 Apr 2026
- 2026From Generation to Collaboration: Using LLMs to Edit for Empathy in Healthcare22 Jan 2026
- 2025Empathy by Design: Aligning Large Language Models for Healthcare Dialogue5 Dec 2025
- 2025Context-Emotion Aware Therapeutic Dialogue Generation: A Multi-component Reinforcement Learning Approach to Language Models for Mental Health Support14 Nov 2025
- 2025RECAP: Transparent Inference-Time Emotion Alignment for Medical Dialogue Systems12 Sep 2025
- 2025HumaniBench: A Human-Centric Framework for Large Multimodal Models Evaluation16 May 2025
- 2025SocialLM: Social Signal Processing of Patient-Provider Communication using LLMs and Contextual Aggregation7 May 2025
- 2025Benchmarking Generative AI for Scoring Medical Student Interviews in Objective Structured Clinical Examinations (OSCEs)21 Jan 2025
- 2024A Multi-Agent Dual Dialogue System to Support Mental Health Care Providers27 Nov 2024
- 2024Script-Strategy Aligned Generation: Aligning LLMs with Expert-Crafted Dialogue Scripts and Therapeutic Strategies for Psychotherapy11 Nov 2024
- 2024Script-Strategy Aligned Generation: Aligning LLMs with Expert-Crafted Dialogue Scripts and Therapeutic Strategies for Psychotherapycited by 7
- 2025Benchmarking Generative AI for Scoring Medical Student Interviews in Objective Structured Clinical Examinations (OSCEs)cited by 7
- 2025RECAP: Transparent Inference-Time Emotion Alignment for Medical Dialogue Systemscited by 3
- 2024The use of GPT-4o and Other Large Language Models for the Improvement and Design of Self-Assessment Scales for Measurement of Interpersonal Communication Skillscited by 1
- 2025SocialLM: Social Signal Processing of Patient-Provider Communication using LLMs and Contextual Aggregationcited by 1
- 2025Context-Emotion Aware Therapeutic Dialogue Generation: A Multi-component Reinforcement Learning Approach to Language Models for Mental Health Supportcited by 0
- 2026From Generation to Collaboration: Using LLMs to Edit for Empathy in Healthcarecited by 0
- 2026LLMs Should Incorporate Explicit Mechanisms for Human Empathycited by 0
- 2026Can "AI" Be a Doctor? A Study of Empathy, Readability, and Alignment in Clinical LLMscited by 0
- 2026Appropriateness of Empathy in AI: A Signal-Cost Perspectivecited by 0
- 2026Appropriateness of Empathy in AI: A Signal-Cost Perspective29 May 2026
- 2026Can "AI" Be a Doctor? A Study of Empathy, Readability, and Alignment in Clinical LLMs22 Apr 2026
- 2026LLMs Should Incorporate Explicit Mechanisms for Human Empathy12 Apr 2026
- 2026From Generation to Collaboration: Using LLMs to Edit for Empathy in Healthcare22 Jan 2026
- 2025Context-Emotion Aware Therapeutic Dialogue Generation: A Multi-component Reinforcement Learning Approach to Language Models for Mental Health Support14 Nov 2025
- 2025RECAP: Transparent Inference-Time Emotion Alignment for Medical Dialogue Systems12 Sep 2025
- 2025SocialLM: Social Signal Processing of Patient-Provider Communication using LLMs and Contextual Aggregation7 May 2025
- 2025Benchmarking Generative AI for Scoring Medical Student Interviews in Objective Structured Clinical Examinations (OSCEs)21 Jan 2025
- 2024Script-Strategy Aligned Generation: Aligning LLMs with Expert-Crafted Dialogue Scripts and Therapeutic Strategies for Psychotherapy11 Nov 2024
- 2024The use of GPT-4o and Other Large Language Models for the Improvement and Design of Self-Assessment Scales for Measurement of Interpersonal Communication Skills21 Sep 2024