mlsanityData to 7 Oct 2026

Improving Biomedical Information Retrieval with Neural Retrievers

arXiv 2201.07745 ↗First posted 19 Jan 2022cs.IR cs.CLcited by 20

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Abstract (arXiv)

Information retrieval (IR) is essential in search engines and dialogue systems as well as natural language processing tasks such as open-domain question answering. IR serve an important function in the biomedical domain, where content and sources of scientific knowledge may evolve rapidly. Although neural retrievers have surpassed traditional IR approaches such as TF-IDF and BM25 in standard open-domain question answering tasks, they are still found lacking in the biomedical domain. In this paper, we seek to improve information retrieval (IR) using neural retrievers (NR) in the biomedical domain, and achieve this goal using a three-pronged approach. First, to tackle the relative lack of data in the biomedical domain, we propose a template-based question generation method that can be leveraged to train neural retriever models. Second, we develop two novel pre-training tasks that are closely aligned to the downstream task of information retrieval. Third, we introduce the ``Poly-DPR'' model which encodes each context into multiple context vectors. Extensive experiments and analysis on the BioASQ challenge suggest that our proposed method leads to large gains over existing neural approaches and beats BM25 in the small-corpus setting. We show that BM25 and our method can complement each other, and a simple hybrid model leads to further gains in the large corpus setting.

Key facts. Cited by 20 papers in the map (data through 7 Oct 2026). Builds on 30 of its 52 references that are in the map. First posted on arXiv 19 Jan 2022.

Builds on

30 of 52 references.

References · 30

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18 more
  1. 2019Passage Re-ranking with BERTcited by 629
  2. 2019Poly-encoders: Transformer Architectures and Pre-training Strategies for Fast and Accurate Multi-sentence Scoringcited by 164
  3. 2020Pre-training Tasks for Embedding-based Large-scale Retrievalcited by 153
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Cited by year (2026 to 7 Oct)

Citing papers per year: 2022: 8; 2023: 4; 2024: 3; 2025: 3; 2026: 2.

20 papers.

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  1. 2022Task-aware Retrieval with Instructionscited by 107
  2. 2022Bridging the Gap Between Indexing and Retrieval for Differentiable Search Index with Query Generationcited by 47
  3. 2024BMRetriever: Tuning Large Language Models as Better Biomedical Text Retrieverscited by 38
  4. 2023End-to-end Knowledge Retrieval with Multi-modal Queriescited by 23
  5. 2022Retrieval augmentation of large language models for lay language generationcited by 21
  6. 2022In-BoXBART: Get Instructions into Biomedical Multi-Task Learningcited by 16
  7. 2022BioTABQA: Instruction Learning for Biomedical Table Question Answeringcited by 13
  8. 2024Assessing Empathy in Large Language Models with Real-World Physician-Patient Interactionscited by 13
  9. 2022Choose Your QA Model Wisely: A Systematic Study of Generative and Extractive Readers for Question Answeringcited by 11
  10. 2023MDDial: A Multi-turn Differential Diagnosis Dialogue Dataset with Reliability Evaluationcited by 10
  11. 2022A Study on the Efficiency and Generalization of Light Hybrid Retrieverscited by 7
  12. 2025Toward Reliable Scientific Hypothesis Generation: Evaluating Truthfulness and Hallucination in Large Language Modelscited by 7
8 more
  1. 2024Medical Dialogue: A Survey of Categories, Methods, Evaluation and Challengescited by 5
  2. 2022Neural Retriever and Go Beyond: A Thesis Proposalcited by 1
  3. 2023Diversifying Knowledge Enhancement of Biomedical Language Models using Adapter Modules and Knowledge Graphscited by 1
  4. 2023Empowering Language Model with Guided Knowledge Fusion for Biomedical Document Re-rankingcited by 0
  5. 2025Cohort Retrieval using Dense Passage Retrievalcited by 0
  6. 2025Investigating LLM Capabilities on Long Context Comprehension for Medical Question Answeringcited by 0
  7. 2026Divide-Prompt-Refine: a Training-Free, Structure-Aware Framework for Biomedical Abstract Generationcited by 0
  8. 2026GrocLM: Grocery Category Recommendation in E-Commerce with Large Language Modelscited by 0