mlsanityData to 7 Oct 2026

Auto-Generating Weak Labels for Real & Synthetic Data to Improve Label-Scarce Medical Image Segmentation

arXiv 2404.17033 ↗First posted 25 Apr 2024cs.CVcited by 3

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Abstract (arXiv)

The high cost of creating pixel-by-pixel gold-standard labels, limited expert availability, and presence of diverse tasks make it challenging to generate segmentation labels to train deep learning models for medical imaging tasks. In this work, we present a new approach to overcome the hurdle of costly medical image labeling by leveraging foundation models like Segment Anything Model (SAM) and its medical alternate MedSAM. Our pipeline has the ability to generate weak labels for any unlabeled medical image and subsequently use it to augment label-scarce datasets. We perform this by leveraging a model trained on a few gold-standard labels and using it to intelligently prompt MedSAM for weak label generation. This automation eliminates the manual prompting step in MedSAM, creating a streamlined process for generating labels for both real and synthetic images, regardless of quantity. We conduct experiments on label-scarce settings for multiple tasks pertaining to modalities ranging from ultrasound, dermatology, and X-rays to demonstrate the usefulness of our pipeline. The code is available at https://github.com/stanfordmlgroup/Auto-Generate-WLs/.

Key facts. Cited by 3 papers in the map (data through 7 Oct 2026). Builds on 23 of its 33 references that are in the map. First posted on arXiv 25 Apr 2024.

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23 of 33 references.

References · 23

  1. 2020Denoising Diffusion Probabilistic Modelscited by 20,851
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  4. 2016V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentationcited by 2,284
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  10. 2022Diffusion Models for Medical Image Analysis: A Comprehensive Surveycited by 269
  11. 2021Diffusion Models for Implicit Image Segmentation Ensemblescited by 198
  12. 2016Skin Lesion Analysis toward Melanoma Detection: A Challenge at the International Symposium on Biomedical Imaging (ISBI) 2016, hosted by the International Skin Imaging Collaboration (ISIC)cited by 197
11 more
  1. 2023UniverSeg: Universal Medical Image Segmentationcited by 90
  2. 2023Input Augmentation with SAM: Boosting Medical Image Segmentation with Segmentation Foundation Modelcited by 56
  3. 2020KiU-Net: Towards Accurate Segmentation of Biomedical Images using Over-complete Representationscited by 49
  4. 2023Computer-Vision Benchmark Segment-Anything Model (SAM) in Medical Images: Accuracy in 12 Datasetscited by 45
  5. 2023Self-Prompting Large Vision Models for Few-Shot Medical Image Segmentationcited by 35
  6. 2023Comprehensive Multimodal Segmentation in Medical Imaging: Combining YOLOv8 with SAM and HQ-SAM Modelscited by 18
  7. 2023Zero-shot performance of the Segment Anything Model (SAM) in 2D medical imaging: A comprehensive evaluation and practical guidelinescited by 15
  8. 2023Zero-Shot Segmentation of Eye Features Using the Segment Anything Model (SAM)cited by 7
  9. 2023CEmb-SAM: Segment Anything Model with Condition Embedding for Joint Learning from Heterogeneous Datasetscited by 3
  10. 2023Self-guided Few-shot Semantic Segmentation for Remote Sensing Imagery Based on Large Vision Modelscited by 2
  11. 2023Empirical Evaluation of the Segment Anything Model (SAM) for Brain Tumor Segmentationcited by 1

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Citing papers per year: 2025: 3.

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  1. 2025Enhancing SAM with Efficient Prompting and Preference Optimization for Semi-supervised Medical Image Segmentation
  2. 2025MedSAM3: Delving into Segment Anything with Medical Concepts
  3. 2025Inpainting is All You Need: A Diffusion-based Augmentation Method for Semi-supervised Medical Image Segmentation
  4. 2024Label Critic: Design Data Before Models
  5. 2026Label-Free Foundational Model Selection for Medical Image Classification under Distribution Shift via Pseudo Label Discrepancy
  6. 2024LaB-RAG: Label Boosted Retrieval Augmented Generation for Radiology Report Generation
  7. 2026Large-Scale Label Quality Assessment for Medical Segmentation via a Vision-Language Judge and Synthetic Data
  8. 2024Exploring Low-Resource Medical Image Classification with Weakly Supervised Prompt Learning