Comprehensive Multimodal Segmentation in Medical Imaging: Combining YOLOv8 with SAM and HQ-SAM Models
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Abstract (arXiv)
This paper introduces a comprehensive approach for segmenting regions of interest (ROI) in diverse medical imaging datasets, encompassing ultrasound, CT scans, and X-ray images. The proposed method harnesses the capabilities of the YOLOv8 model for approximate boundary box detection across modalities, alongside the Segment Anything Model (SAM) and High Quality (HQ) SAM for fully automatic and precise segmentation. To generate boundary boxes, the YOLOv8 model was trained using a limited set of 100 images and masks from each modality. The results obtained from our approach are extensively computed and analyzed, demonstrating its effectiveness and potential in medical image analysis. Various evaluation metrics, including precision, recall, F1 score, and Dice Score, were employed to quantify the accuracy of the segmentation results. A comparative analysis was conducted to assess the individual and combined performance of the YOLOv8, YOLOv8+SAM, and YOLOv8+HQ-SAM models. The results indicate that the SAM model performs better than the other two models, exhibiting higher segmentation accuracy and overall performance. While HQ-SAM offers potential advantages, its incremental gains over the standard SAM model may not justify the additional computational cost. The YOLOv8+SAM model shows promise for enhancing medical image segmentation and its clinical implications.
Key facts. Cited by 18 papers in the map (data through 7 Oct 2026). Builds on 11 of its 19 references that are in the map. First posted on arXiv 4 Oct 2023.
Builds on
11 of 19 references.
References · 11
- 2017Attention Is All You Needcited by 59,932
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
- 2023Segment Anythingcited by 8,158
- 2018Encoder-Decoder with Atrous Separable Convolution for Semantic Image Segmentationcited by 3,210
- 2017Rethinking Atrous Convolution for Semantic Image Segmentationcited by 2,154
- 2021TransUNet: Transformers Make Strong Encoders for Medical Image Segmentationcited by 1,552
- 20163D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotationcited by 1,471
- 2018Attention U-Net: Learning Where to Look for the Pancreascited by 1,420
- 2023Segment Anything in High Qualitycited by 373
- 2020Improving Semantic Segmentation via Decoupled Body and Edge Supervisioncited by 98
- 2017Deep Learning for Multi-Task Medical Image Segmentation in Multiple Modalitiescited by 25
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Citing papers per year: 2023: 1; 2024: 7; 2025: 8; 2026: 2.
18 papers.
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- 2024Segment Anything Model for Medical Image Segmentation: Current Applications and Future Directionscited by 97
- 2024Foundation Model for Advancing Healthcare: Challenges, Opportunities, and Future Directionscited by 77
- 2024Test-Time Adaptation with SaLIP: A Cascade of SAM and CLIP for Zero shot Medical Image Segmentationcited by 25
- 2025DC-SAM: In-Context Segment Anything in Images and Videos via Dual Consistencycited by 15
- 2023A Systematic Review of Deep Learning-based Research on Radiology Report Generationcited by 14
- 2024SAM-MPA: Applying SAM to Few-shot Medical Image Segmentation using Mask Propagation and Auto-promptingcited by 9
- 2025Recent Advances in Medical Imaging Segmentation: A Surveycited by 8
- 2024Auto-Generating Weak Labels for Real & Synthetic Data to Improve Label-Scarce Medical Image Segmentationcited by 3
- 2025Segment Anything for Video: A Comprehensive Review of Video Object Segmentation and Tracking from Past to Futurecited by 2
- 2024FusionSAM: Visual Multi-Modal Learning with Segment Anythingcited by 1
- 2025Semi-Supervised Medical Image Segmentation via Knowledge Mining from Large Modelscited by 1
- 2026RobustMedSAM: Degradation-Resilient Medical Image Segmentation via Robust Foundation Model Adaptationcited by 1
6 more
- 2024Multi-Stage Segmentation and Cascade Classification Methods for Improving Cardiac MRI Analysiscited by 0
- 2025AutoMiSeg: Automatic Medical Image Segmentation via Test-Time Adaptation of Foundation Modelscited by 0
- 2025Geometric Feature Prompting of Image Segmentation Modelscited by 0
- 2025Real-Time Threaded Houbara Detection and Segmentation for Wildlife Conservation using Mobile Platformscited by 0
- 2025Neural expressiveness for beyond importance model compressioncited by 0
- 2026Dissecting Model Failures in Abdominal Aortic Aneurysm Segmentation through Explainability-Driven Analysiscited by 0
- 2026RobustMedSAM: Degradation-Resilient Medical Image Segmentation via Robust Foundation Model Adaptation10 Apr 2026
- 2026Dissecting Model Failures in Abdominal Aortic Aneurysm Segmentation through Explainability-Driven Analysis25 Mar 2026
- 2025Neural expressiveness for beyond importance model compression6 Dec 2025
- 2025Real-Time Threaded Houbara Detection and Segmentation for Wildlife Conservation using Mobile Platforms3 Oct 2025
- 2025Segment Anything for Video: A Comprehensive Review of Video Object Segmentation and Tracking from Past to Future30 Jul 2025
- 2025Geometric Feature Prompting of Image Segmentation Models27 May 2025
- 2025AutoMiSeg: Automatic Medical Image Segmentation via Test-Time Adaptation of Foundation Models23 May 2025
- 2025Recent Advances in Medical Imaging Segmentation: A Survey14 May 2025
- 2025DC-SAM: In-Context Segment Anything in Images and Videos via Dual Consistency16 Apr 2025
- 2025Semi-Supervised Medical Image Segmentation via Knowledge Mining from Large Models10 Mar 2025
- 2024Multi-Stage Segmentation and Cascade Classification Methods for Improving Cardiac MRI Analysis12 Dec 2024
- 2024SAM-MPA: Applying SAM to Few-shot Medical Image Segmentation using Mask Propagation and Auto-prompting26 Nov 2024
6 more
- 2024FusionSAM: Visual Multi-Modal Learning with Segment Anything26 Aug 2024
- 2024Auto-Generating Weak Labels for Real & Synthetic Data to Improve Label-Scarce Medical Image Segmentation25 Apr 2024
- 2024Test-Time Adaptation with SaLIP: A Cascade of SAM and CLIP for Zero shot Medical Image Segmentation9 Apr 2024
- 2024Foundation Model for Advancing Healthcare: Challenges, Opportunities, and Future Directions4 Apr 2024
- 2024Segment Anything Model for Medical Image Segmentation: Current Applications and Future Directions7 Jan 2024
- 2023A Systematic Review of Deep Learning-based Research on Radiology Report Generation23 Nov 2023
- 2024Segment Anything Model for Medical Image Segmentation: Current Applications and Future Directionscited by 97
- 2024Foundation Model for Advancing Healthcare: Challenges, Opportunities, and Future Directionscited by 77
- 2024Test-Time Adaptation with SaLIP: A Cascade of SAM and CLIP for Zero shot Medical Image Segmentationcited by 25
- 2025DC-SAM: In-Context Segment Anything in Images and Videos via Dual Consistencycited by 15
- 2023A Systematic Review of Deep Learning-based Research on Radiology Report Generationcited by 14
- 2024SAM-MPA: Applying SAM to Few-shot Medical Image Segmentation using Mask Propagation and Auto-promptingcited by 9
- 2025Recent Advances in Medical Imaging Segmentation: A Surveycited by 8
- 2024Auto-Generating Weak Labels for Real & Synthetic Data to Improve Label-Scarce Medical Image Segmentationcited by 3
- 2025Segment Anything for Video: A Comprehensive Review of Video Object Segmentation and Tracking from Past to Futurecited by 2
- 2024FusionSAM: Visual Multi-Modal Learning with Segment Anythingcited by 1
- 2025Semi-Supervised Medical Image Segmentation via Knowledge Mining from Large Modelscited by 1
- 2026RobustMedSAM: Degradation-Resilient Medical Image Segmentation via Robust Foundation Model Adaptationcited by 1
12 most cited of 18 All 18 (JSON)
- 2026RobustMedSAM: Degradation-Resilient Medical Image Segmentation via Robust Foundation Model Adaptation10 Apr 2026
- 2026Dissecting Model Failures in Abdominal Aortic Aneurysm Segmentation through Explainability-Driven Analysis25 Mar 2026
- 2025Neural expressiveness for beyond importance model compression6 Dec 2025
- 2025Real-Time Threaded Houbara Detection and Segmentation for Wildlife Conservation using Mobile Platforms3 Oct 2025
- 2025Segment Anything for Video: A Comprehensive Review of Video Object Segmentation and Tracking from Past to Future30 Jul 2025
- 2025Geometric Feature Prompting of Image Segmentation Models27 May 2025
- 2025AutoMiSeg: Automatic Medical Image Segmentation via Test-Time Adaptation of Foundation Models23 May 2025
- 2025Recent Advances in Medical Imaging Segmentation: A Survey14 May 2025
- 2025DC-SAM: In-Context Segment Anything in Images and Videos via Dual Consistency16 Apr 2025
- 2025Semi-Supervised Medical Image Segmentation via Knowledge Mining from Large Models10 Mar 2025
- 2024Multi-Stage Segmentation and Cascade Classification Methods for Improving Cardiac MRI Analysis12 Dec 2024
- 2024SAM-MPA: Applying SAM to Few-shot Medical Image Segmentation using Mask Propagation and Auto-prompting26 Nov 2024
12 newest of 18 All 18 (JSON)